6KLB
| Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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4A7D
| X-ray crystal structure of HEWL flash-cooled at high pressure | 分子名称: | CHLORIDE ION, LYSOZYME C, SODIUM ION | 著者 | Burkhardt, A, Warmer, M, Panneerselvam, S, Wagner, A, Reimer, R, Hohenberg, H, Meents, A. | 登録日 | 2011-11-14 | 公開日 | 2011-11-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | 主引用文献 | Fast High-Pressure Freezing of Protein Crystals in Their Mother Liquor Acta Crystallogr.,Sect.F, 68, 2012
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4A7E
| X-ray crystal structure of porcine insulin flash-cooled at high pressure | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN | 著者 | Burkhardt, A, Warmer, M, Panneerselvam, S, Wagner, A, Reimer, R, Hohenberg, H, Meents, A. | 登録日 | 2011-11-14 | 公開日 | 2011-11-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.856 Å) | 主引用文献 | Fast High-Pressure Freezing of Protein Crystals in Their Mother Liquor Acta Crystallogr.,Sect.F, 68, 2012
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6KN4
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4BBT
| The PR1 Photocycle Intermediate of Photoactive Yellow Protein | 分子名称: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | 著者 | Schotte, F, Cho, H.S, Kaila, V.R.I, Kamikubo, H, Dashdorj, N, Henry, E.R, Graber, T.J, Henning, R, Wulff, M, Hummer, G, Kataoka, M, Anfinrud, P.A. | 登録日 | 2012-09-27 | 公開日 | 2012-11-14 | 最終更新日 | 2019-01-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Watching a Signaling Protein Function in Real Time Via 100-Ps Time-Resolved Laue Crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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4B91
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4B08
| Yeast DNA polymerase alpha, Selenomethionine protein | 分子名称: | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A | 著者 | Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. | 登録日 | 2012-06-29 | 公開日 | 2013-02-27 | 最終更新日 | 2013-05-01 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha Elife, 2, 2013
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4AV1
| Crystal structure of the human PARP-1 DNA binding domain in complex with DNA | 分子名称: | 5'-D(*AP*AP*GP*TP*GP*TP*TP*GP*CP*AP*TP*TP)-3', 5'-D(*TP*AP*AP*TP*GP*CP*AP*AP*CP*AP*CP*TP)-3', POLY [ADP-RIBOSE] POLYMERASE 1, ... | 著者 | Ali, A.A.E, Timinszky, G, Arribas-Bosacoma, R, Kozlowski, M, Hassa, P.O, Hassler, M, Ladurner, A.G, Pearl, L.H, Oliver, A.W. | 登録日 | 2012-05-23 | 公開日 | 2012-06-13 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Zinc-Finger Domains of Parp1 Cooperate to Recognise DNA Strand-Breaks Nat.Struct.Mol.Biol., 19, 2012
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1ST2
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4B0Q
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6JXV
| SUMO1 bound to phosphorylated SLS4-SIM peptide from ICP0 | 分子名称: | Phosphorylated SLS4-SIM from ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6JXU
| SUMO1 bound to SLS4-SIM peptide from ICP0 | 分子名称: | Small ubiquitin-related modifier, viral protein | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6KNA
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6JXW
| Complex of SUMO2 bound SLS4 from ICP0. | 分子名称: | SLS4-SIM from Ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier 2 | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6JXX
| SUMO2 bound to phosphorylated SLS4-SIM peptide from ICP0 | 分子名称: | Phosphorylated SLS4 from E3 ubiquitin ligase ICP0, Small ubiquitin-related modifier 2 | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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4B3J
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4B90
| Crystal structure of WT human CRMP-5 | 分子名称: | 1,2-ETHANEDIOL, DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 | 著者 | Ponnusamy, R, Lohkamp, B. | 登録日 | 2012-08-31 | 公開日 | 2013-02-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights Into the Oligomerization of Crmps: Crystal Structure of Human Collapsin Response Mediator Protein 5. J.Neurochem., 125, 2013
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4BDF
| Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) | 分子名称: | 1,2-ETHANEDIOL, 5-METHYL-3-PHENYL-1H-PYRAZOLE, NITRATE ION, ... | 著者 | Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M. | 登録日 | 2012-10-05 | 公開日 | 2013-06-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2. Plos One, 8, 2013
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6KG1
| NifS from Helicobacter pylori, soaked with L-cysteine for 180 sec | 分子名称: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, CHLORIDE ION, Cysteine desulfurase IscS, ... | 著者 | Nakamura, R, Takahashi, Y, Fujishiro, T. | 登録日 | 2019-07-09 | 公開日 | 2019-10-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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3R0T
| Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-5279 | 分子名称: | 1,2-ETHANEDIOL, 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, ... | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2011-03-09 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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4ARL
| Structure of the inactive pesticin D207A mutant | 分子名称: | PESTICIN | 著者 | Zeth, K, Patzer, S.I, Albrecht, R, Braun, V. | 登録日 | 2012-04-25 | 公開日 | 2012-05-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Structure and Mechanistic Studies of Pesticin, a Bacterial Homolog of Phage Lysozymes. J.Biol.Chem., 287, 2012
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4ASL
| Structure of Epa1A in complex with the T-antigen (Gal-b1-3- GalNAc) | 分子名称: | CALCIUM ION, EPA1P, GLYCEROL, ... | 著者 | Maestre-Reyna, M, Diderrich, R, Veelders, M.S, Eulenburg, G, Kalugin, V, Brueckner, S, Keller, P, Rupp, S, Moesch, H.-U, Essen, L.-O. | 登録日 | 2012-05-02 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Structural Basis for Promiscuity and Specificity During Candida Glabrata Invasion of Host Epithelia. Proc.Natl.Acad.Sci.USA, 109, 2012
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6KG0
| NifS from Helicobacter pylori, soaked with L-cysteine for 118 sec | 分子名称: | CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... | 著者 | Nakamura, R, Takahashi, Y, Fujishiro, T. | 登録日 | 2019-07-09 | 公開日 | 2019-10-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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4ATT
| FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl para methoxy phenyl | 分子名称: | 3-(4-methoxyphenyl)prop-2-yn-1-yl alpha-D-mannopyranoside, FIMH | 著者 | Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R. | 登録日 | 2012-05-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.251 Å) | 主引用文献 | Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of Fimh. Acs Med.Chem.Lett., 4, 2013
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4AUY
| Structure of the FimH lectin domain in the trigonal space group, in complex with an hydroxyl propynyl phenyl alpha-D-mannoside at 2.1 A resolution | 分子名称: | 4-(3-hydroxyprop-1-yn-1-yl)phenyl alpha-D-mannopyranoside, FIMH, NICKEL (II) ION, ... | 著者 | Wellens, A, Lahmann, M, Touaibia, M, Vaucher, J, Oscarson, S, Roy, R, Remaut, H, Bouckaert, J. | 登録日 | 2012-05-22 | 公開日 | 2012-06-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh. Biochemistry, 51, 2012
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