4NXO
| Crystal Structure of Insulin Degrading Enzyme in complex with BDM44768 | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Liang, W.G, Deprez, R, Deprez, B, Tang, W. | 登録日 | 2013-12-09 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Nat Commun, 6, 2015
|
|
3WAX
| Crystal Structure of Autotaxin in Complex with 3BoA | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
|
|
3WG3
| Crystal structure of Agrocybe cylindracea galectin with blood type A antigen tetraose | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Galactoside-binding lectin, ... | 著者 | Kuwabara, N, Hu, D, Tateno, H, Makio, H, Hirabayashi, J, Kato, R. | 登録日 | 2013-07-25 | 公開日 | 2013-11-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Conformational change of a unique sequence in a fungal galectin from Agrocybe cylindracea controls glycan ligand-binding specificity. Febs Lett., 587, 2013
|
|
3WGD
| Crystal structure of ERp46 Trx1 | 分子名称: | GLYCEROL, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Inaba, K, Suzuki, M, Kojima, R. | 登録日 | 2013-08-04 | 公開日 | 2014-06-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Radically different thioredoxin domain arrangement of ERp46, an efficient disulfide bond introducer of the mammalian PDI family Structure, 22, 2014
|
|
6H88
| MamM CTD D249N | 分子名称: | BETA-MERCAPTOETHANOL, Magnetosome protein MamM, Cation efflux protein family | 著者 | Barber-Zucker, S, Zarivach, R. | 登録日 | 2018-08-02 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | MamM CTD D249N To Be Published
|
|
3WGX
| Crystal structure of ERp46 Trx2 in a complex with Prx4 C-term | 分子名称: | GLYCEROL, Peroxiredoxin-4, Thioredoxin domain-containing protein 5 | 著者 | Inaba, K, Suzuki, M, Kojima, R. | 登録日 | 2013-08-13 | 公開日 | 2014-06-25 | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | 主引用文献 | Radically different thioredoxin domain arrangement of ERp46, an efficient disulfide bond introducer of the mammalian PDI family Structure, 22, 2014
|
|
3WD7
| Type III polyketide synthase | 分子名称: | COENZYME A, NICKEL (II) ION, SULFATE ION, ... | 著者 | Mori, T, Shimokawa, Y, Matsui, T, Kato, R, Sugio, S, Morita, H, Abe, I. | 登録日 | 2013-06-10 | 公開日 | 2013-09-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa To be Published
|
|
3WIV
| |
1RTH
| HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES | 分子名称: | 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE, HIV-1 REVERSE TRANSCRIPTASE | 著者 | Ren, J, Esnouf, R, Garman, E, Somers, D, Ross, C, Kirby, I, Keeling, J, Darby, G, Jones, Y, Stuart, D, Stammers, D. | 登録日 | 1995-05-03 | 公開日 | 1996-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Nat.Struct.Biol., 2, 1995
|
|
6H8F
| Fragment of the C-terminal domain of the TssA component of the type VI secretion system from Burkholderia cenocepacia | 分子名称: | TssA | 著者 | Dix, S.R, Owen, H.J, Sun, R, Ahmad, A, Shastri, S, Spiewak, H.L, Mosby, D.J, Harris, M.J, Batters, S.L, Brooker, T.A, Tzokov, S.B, Sedelnikova, S.E, Baker, P.J, Bullough, P.A, Rice, D.W, Thomas, M.S. | 登録日 | 2018-08-02 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural insights into the function of type VI secretion system TssA subunits. Nat Commun, 9, 2018
|
|
6H8G
| |
3WMP
| Crystal structure of SLL-2 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kita, A, Jimbo, M, Sakai, R, Morimoto, Y, Miki, K. | 登録日 | 2013-11-22 | 公開日 | 2015-01-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a symbiosis-related lectin from octocoral. Glycobiology, 25, 2015
|
|
1RYX
| |
6HJK
| Crystal Structure of Aurora-A L210C catalytic domain in complex with ASDO2 | 分子名称: | (~{E})-~{N}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-but-2-enamide, Aurora kinase A, CHLORIDE ION, ... | 著者 | Bayliss, R, McIntyre, P.J. | 登録日 | 2018-09-04 | 公開日 | 2018-10-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases. ACS Chem. Biol., 13, 2018
|
|
4NR7
| Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand | 分子名称: | 1,2-ETHANEDIOL, 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole, CREB-binding protein | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Hay, D, Fedorov, O, Martin, S, Krojer, T, Nowak, R, von Delft, F, Brennan, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-11-26 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand To be Published
|
|
6HJX
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cys-loop ligand-gated ion channel, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Spurny, R, Govaerts, C, Evans, G.L, Pardon, E, Steyaert, J, Ulens, C. | 登録日 | 2018-09-04 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A lipid site shapes the agonist response of a pentameric ligand-gated ion channel. Nat.Chem.Biol., 15, 2019
|
|
6HKN
| Crystal structure of Compound 35 with ERK5 | 分子名称: | Mitogen-activated protein kinase 7, [2-azanyl-4-(trifluoromethyloxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone | 著者 | Nguyen, D, Lemos, C, Wortmann, L, Eis, K, Holton, S.J, Boemer, U, Lechner, C, Prechtl, S, Suelze, D, Siegel, F, Prinz, F, Lesche, R, Nicke, B, Mumberg, D, Bauser, M, Haegebarth, A. | 登録日 | 2018-09-07 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5. J. Med. Chem., 62, 2019
|
|
1S3H
| Propionibacterium shermanii transcarboxylase 5S subunit A59T | 分子名称: | COBALT (II) ION, transcarboxylase 5S subunit | 著者 | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | 登録日 | 2004-01-13 | 公開日 | 2004-09-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
|
|
3WAP
| Crystal structure of Atg13 LIR-fused human LC3C_8-125 | 分子名称: | Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3C | 著者 | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | 登録日 | 2013-05-06 | 公開日 | 2013-12-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism. Structure, 22, 2014
|
|
3WAV
| Crystal Structure of Autotaxin in Complex with Compound 10 | 分子名称: | (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-05-09 | 公開日 | 2013-07-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | 主引用文献 | Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
|
|
6HNX
| |
6HO1
| |
3WNQ
| Crystal structure of (R)-carbonyl reductase H49A mutant from Candida Parapsilosis in complex with 2-hydroxyacetophenone | 分子名称: | (R)-specific carbonyl reductase, 2-hydroxy-1-phenylethanone, ZINC ION | 著者 | Wang, S.S, Nie, Y, Xu, Y, Zhang, R.Z, Huang, C.H, Chan, H.C, Guo, R.T, Ko, T.P, Xiao, R. | 登録日 | 2013-12-15 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Unconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenase Chem.Commun.(Camb.), 50, 2014
|
|
6HO5
| |
6HOG
| Structure of VPS34 LIR motif bound to GABARAP | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, ... | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | 登録日 | 2018-09-17 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
|
|