6CKA
 
 | | Crystal Structure of Paratox | | Descriptor: | Paratox | | Authors: | Prehna, G. | | Deposit date: | 2018-02-27 | | Release date: | 2018-11-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.559 Å) | | Cite: | The conserved mosaic prophage protein paratox inhibits the natural competence regulator ComR in Streptococcus.
Sci Rep, 8, 2018
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2H7V
 | | Co-crystal structure of YpkA-Rac1 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Migration-inducing protein 5, ... | | Authors: | Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E. | | Deposit date: | 2006-06-04 | | Release date: | 2006-09-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors.
Cell(Cambridge,Mass.), 126, 2006
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5FD4
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5HTF
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2H7O
 | | Crystal structure of the Rho-GTPase binding domain of YpkA | | Descriptor: | Protein kinase ypkA | | Authors: | Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E. | | Deposit date: | 2006-06-02 | | Release date: | 2006-09-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors.
Cell(Cambridge,Mass.), 126, 2006
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2P2L
 | | Rac1-GDP-Zinc Complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION | | Authors: | Prehna, G, Stebbins, C.E. | | Deposit date: | 2007-03-07 | | Release date: | 2007-05-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium.
Acta Crystallogr.,Sect.D, 63, 2007
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2LQV
 | | YebF | | Descriptor: | Protein yebF | | Authors: | Prehna, G, Zhang, G, Gong, X, Duszyk, M, Okon, M, Mcintosh, L.P, Weiner, J.H, Strynadka, N.C.J. | | Deposit date: | 2012-03-16 | | Release date: | 2012-06-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A Protein Export Pathway Involving Escherichia coli Porins.
Structure, 20, 2012
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2LV4
 | | ZirS C-terminal Domain | | Descriptor: | Putative outer membrane or exported protein | | Authors: | Prehna, G, Li, Y, Stoynov, N, Okon, M, Vukovic, M, Mcintosh, L.P, Foster, L.J, Finlay, B, Strynadka, N.C.J. | | Deposit date: | 2012-06-28 | | Release date: | 2012-08-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The zinc regulated antivirulence pathway of salmonella is a multiprotein immunoglobulin adhesion system.
J.Biol.Chem., 287, 2012
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8SPM
 | | Crystal structure of NikA in complex Ni-AMA | | Descriptor: | Aspergillomarasmine A, NICKEL (II) ION, Nickel ABC transporter, ... | | Authors: | Sychantha, D, Prehna, G, Wright, G.D. | | Deposit date: | 2023-05-03 | | Release date: | 2024-04-10 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes.
Nat Commun, 15, 2024
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8SXQ
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7RT7
 | | Crystal structure of the RhsP2 C-terminal toxin domain in complex with its immunity protein, RhsI2 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhsI2, RhsP2 | | Authors: | Bullen, N.P, Prehna, G, Whitney, J.C. | | Deposit date: | 2021-08-12 | | Release date: | 2022-08-17 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs.
Mol.Cell, 82, 2022
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7UMA
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7UO3
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7UO8
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7MK5
 | | Crystal structure of Escherichia coli ClpP covalently inhibited by clipibicyclene | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-[(1E)-3-{[(2E,4E,6E,8S)-8-hydroxy-4-methyldeca-2,4,6-trienoyl]amino}-3-oxoprop-1-en-1-yl]azete-1(2H)-carboxylic acid, ACETATE ION, ... | | Authors: | Culp, E.J, Sychantha, D, Hobson, C, Pawlowski, A.J, Prehna, G, Wright, G.D. | | Deposit date: | 2021-04-21 | | Release date: | 2022-02-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | ClpP inhibitors are produced by a widespread family of bacterial gene clusters.
Nat Microbiol, 7, 2022
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6XRR
 | | Structure of SciW bound to the Rhs1 Transmembrane Domain from Salmonella typhimurium | | Descriptor: | Putative cytoplasmic protein, RHS repeat protein, SULFATE ION | | Authors: | Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. | | Deposit date: | 2020-07-13 | | Release date: | 2020-12-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones.
Elife, 9, 2020
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6XRF
 | | EagT6 Tse6 NT complex | | Descriptor: | Effector EagT6, PAAR motif family protein | | Authors: | Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. | | Deposit date: | 2020-07-12 | | Release date: | 2020-12-30 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones.
Elife, 9, 2020
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4J94
 | | Crystal structure of MycP1 from the ESX-1 type VII secretion system | | Descriptor: | Membrane-anchored mycosin mycp1 | | Authors: | Solomonson, M, Wasney, G.A, Watanabe, N, Gruninger, R.J, Prehna, G, Strynadka, N.C.J. | | Deposit date: | 2013-02-15 | | Release date: | 2013-05-01 | | Last modified: | 2013-07-03 | | Method: | X-RAY DIFFRACTION (1.857 Å) | | Cite: | Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System.
J.Biol.Chem., 288, 2013
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4KPG
 | | Crystal structure of MycP1 from the ESX-1 type VII secretion system | | Descriptor: | Membrane-anchored mycosin mycp1 | | Authors: | Solomonson, M, Wasney, G.A, Watanabe, N, Gruninger, R.J, Prehna, G, Strynadka, N.C.J. | | Deposit date: | 2013-05-13 | | Release date: | 2013-05-22 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.148 Å) | | Cite: | Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System.
J.Biol.Chem., 288, 2013
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6XRB
 | | Crystal structure of SciW from Salmonella typhimurium | | Descriptor: | SciW, TRIETHYLENE GLYCOL | | Authors: | Sachar, K, Ahmad, S, Whitney, J.C, Prehna, G. | | Deposit date: | 2020-07-11 | | Release date: | 2020-12-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones.
Elife, 9, 2020
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7N1N
 | | Prx in complex with ComR DNA-binding domain | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ComR, Prx | | Authors: | Rutbeek, N.R, Prehna, G. | | Deposit date: | 2021-05-27 | | Release date: | 2021-07-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox.
J.Biol.Chem., 297, 2021
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7N10
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