5FW0
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![BU of 5fw0 by Molmil](/molmil-images/mine/5fw0) | Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2-(5-((2-methoxyethyl)(methyl)amino)pyridin-3-yl) ethyl)-4-methylpyridin-2-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(2-(5-((2-methoxyethyl)(methyl)amino)pyridin-3-yl)ethyl)-4-methylpyridin-2-amine, ACETATE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2016-02-10 | Release date: | 2016-04-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker. J.Med.Chem., 59, 2016
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5G6J
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5G6E
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![BU of 5g6e by Molmil](/molmil-images/mine/5g6e) | Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-(((3-(PYRIDIN-3-YL)PROPYL)AMINO)METHYL)QUINOLIN-2-, CHLORIDE ION, ... | Authors: | Holden, J.K, Poulos, T.L. | Deposit date: | 2016-06-18 | Release date: | 2016-09-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.111 Å) | Cite: | Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry, 55, 2016
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5G0N
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![BU of 5g0n by Molmil](/molmil-images/mine/5g0n) | Structure of rat neuronal nitric oxide synthase D597N mutant heme domain in complex with N1-(5-(2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL) PYRIDIN-3-YL)-N1,N2-DIMETHYLETHANE-1,2-DIAMINE | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)-N1,N2-dimethylethane-1,2-diamine, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2016-03-21 | Release date: | 2016-06-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.936 Å) | Cite: | Electrostatic Control of Isoform Selective Inhibitor Binding in Nitric Oxide Synthase. Biochemistry, 55, 2016
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5G0O
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![BU of 5g0o by Molmil](/molmil-images/mine/5g0o) | Structure of rat neuronal nitric oxide synthase D597N mutant heme domain in complex with 4-METHYL-6-(2-(5-(4-METHYLPIPERAZIN-1-YL) PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE | Descriptor: | 4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl)ethyl)pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2016-03-21 | Release date: | 2016-06-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Electrostatic Control of Isoform Selective Inhibitor Binding in Nitric Oxide Synthase. Biochemistry, 55, 2016
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1BVY
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![BU of 1bvy by Molmil](/molmil-images/mine/1bvy) | COMPLEX OF THE HEME AND FMN-BINDING DOMAINS OF THE CYTOCHROME P450(BM-3) | Descriptor: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, PROTEIN (CYTOCHROME P450 BM-3), ... | Authors: | Sevrioukova, I.F, Li, H, Zhang, H, Peterson, J.A, Poulos, T.L. | Deposit date: | 1998-09-21 | Release date: | 1999-02-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structure of a cytochrome P450-redox partner electron-transfer complex. Proc.Natl.Acad.Sci.USA, 96, 1999
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1ATJ
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![BU of 1atj by Molmil](/molmil-images/mine/1atj) | RECOMBINANT HORSERADISH PEROXIDASE C1A | Descriptor: | CALCIUM ION, PEROXIDASE C1A, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gajhede, M, Schuller, D.J, Henriksen, A, Smith, A.T, Poulos, T.L. | Deposit date: | 1997-08-14 | Release date: | 1998-02-04 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of horseradish peroxidase C at 2.15 A resolution. Nat.Struct.Biol., 4, 1997
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4CP4
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1TWN
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![BU of 1twn by Molmil](/molmil-images/mine/1twn) | |
1SCH
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![BU of 1sch by Molmil](/molmil-images/mine/1sch) | PEANUT PEROXIDASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PEANUT PEROXIDASE, ... | Authors: | Schuller, D.J, Poulos, T.L. | Deposit date: | 1996-01-23 | Release date: | 1996-07-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | The crystal structure of peanut peroxidase. Structure, 4, 1996
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1S8C
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![BU of 1s8c by Molmil](/molmil-images/mine/1s8c) | Crystal structure of human heme oxygenase in a complex with biliverdine | Descriptor: | BILIVERDINE IX ALPHA, Heme oxygenase 1 | Authors: | Lad, L, Friedman, J, Li, H, Bhaskar, B, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2004-02-02 | Release date: | 2004-08-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal Structure of Human Heme Oxygenase-1 in a Complex with Biliverdin Biochemistry, 43, 2004
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1STQ
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![BU of 1stq by Molmil](/molmil-images/mine/1stq) | Cyrstal Structure of Cytochrome c Peroxidase Mutant: CcPK2M3 | Descriptor: | Cytochrome c peroxidase, mitochondrial, POTASSIUM ION, ... | Authors: | Barrows, T.P, Bhaskar, B, Poulos, T.L. | Deposit date: | 2004-03-25 | Release date: | 2004-07-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Electrostatic control of the tryptophan radical in cytochrome c peroxidase. Biochemistry, 43, 2004
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1T2B
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![BU of 1t2b by Molmil](/molmil-images/mine/1t2b) | Crystal Structure of cytochrome P450cin complexed with its substrate 1,8-cineole | Descriptor: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Meharenna, Y.T, Li, H, Hawkes, D.B, Pearson, A.G, De Voss, J, Poulos, T.L. | Deposit date: | 2004-04-20 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam Biochemistry, 43, 2004
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1T85
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![BU of 1t85 by Molmil](/molmil-images/mine/1t85) | Crystal Structure of the Ferrous CO-bound Cytochrome P450cam Mutant (L358P/C334A) | Descriptor: | CAMPHOR, CARBON MONOXIDE, Cytochrome P450-cam, ... | Authors: | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | Deposit date: | 2004-05-11 | Release date: | 2004-06-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T86
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![BU of 1t86 by Molmil](/molmil-images/mine/1t86) | Crystal Structure of the Ferrous Cytochrome P450cam Mutant (L358P/C334A) | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | Deposit date: | 2004-05-11 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T87
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![BU of 1t87 by Molmil](/molmil-images/mine/1t87) | Crystal Structure of the Ferrous CO-bound Cytochrome P450cam (C334A) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CARBON MONOXIDE, ... | Authors: | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | Deposit date: | 2004-05-11 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T88
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![BU of 1t88 by Molmil](/molmil-images/mine/1t88) | Crystal Structure of the Ferrous Cytochrome P450cam (C334A) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | Authors: | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | Deposit date: | 2004-05-11 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T5P
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![BU of 1t5p by Molmil](/molmil-images/mine/1t5p) | Human Heme Oxygenase Oxidation of alpha- and gamma-meso-phenylhemes | Descriptor: | 12-PHENYLHEME, Heme oxygenase 1 | Authors: | Wang, J, Niemevz, F, Lad, L, Buldain, G, Poulos, T.L, Ortiz de Montellano, P.R. | Deposit date: | 2004-05-05 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Human heme oxygenase oxidation of 5- and 15-phenylhemes. J.Biol.Chem., 279, 2004
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1TWR
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![BU of 1twr by Molmil](/molmil-images/mine/1twr) | |
1S13
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![BU of 1s13 by Molmil](/molmil-images/mine/1s13) | Human Heme Oxygenase Oxidatition of alpha- and gamma-meso-Phenylhemes | Descriptor: | 2-PHENYLHEME, Heme oxygenase 1 | Authors: | Wang, J, Niemevz, F, Lad, L, Buldain, G, Poulos, T.L, Ortiz de Montellano, P.R. | Deposit date: | 2004-01-05 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Human heme oxygenase oxidation of 5- and 15-phenylhemes. J.Biol.Chem., 279, 2004
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1S6V
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![BU of 1s6v by Molmil](/molmil-images/mine/1s6v) | Structure of a cytochrome c peroxidase-cytochrome c site specific cross-link | Descriptor: | Cytochrome c peroxidase, mitochondrial, Cytochrome c, ... | Authors: | Guo, M, Bhaskar, B, Li, H, Barrows, T.P, Poulos, T.L. | Deposit date: | 2004-01-27 | Release date: | 2004-04-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structure and characterization of a cytochrome c peroxidase-cytochrome c site-specific cross-link Proc.Natl.Acad.Sci.USA, 101, 2004
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1SOG
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1EA1
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![BU of 1ea1 by Molmil](/molmil-images/mine/1ea1) | Cytochrome P450 14 alpha-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with fluconazole | Descriptor: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, CYTOCHROME P450 51-LIKE RV0764C, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Podust, L.M, Poulos, T.L, Waterman, M.R. | Deposit date: | 2000-11-02 | Release date: | 2000-11-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal Structure of Cytochrome P450 14Alpha -Sterol Demethylase (Cyp51) from Mycobacterium Tuberculosis in Complex with Azole Inhibitors Proc.Natl.Acad.Sci.USA, 98, 2001
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1F4U
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![BU of 1f4u by Molmil](/molmil-images/mine/1f4u) | THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS | Descriptor: | CYTOCHROME P450 119, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Yano, J.K, Koo, L.S, Schuller, D.J, Li, H, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2000-06-09 | Release date: | 2000-10-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus. J.Biol.Chem., 275, 2000
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1F4T
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![BU of 1f4t by Molmil](/molmil-images/mine/1f4t) | THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS WITH 4-PHENYLIMIDAZOLE BOUND | Descriptor: | 4-PHENYL-1H-IMIDAZOLE, CYTOCHROME P450 119, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Yano, J.K, Koo, L.S, Schuller, D.J, Li, H, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2000-06-09 | Release date: | 2000-10-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus. J.Biol.Chem., 275, 2000
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