4I02
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![BU of 4i02 by Molmil](/molmil-images/mine/4i02) | structure of the mutant Catabolite gene activator protein V140A | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. | Deposit date: | 2012-11-16 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
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4I0B
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![BU of 4i0b by Molmil](/molmil-images/mine/4i0b) | structure of the mutant Catabolite gene activator protein H160L | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. | Deposit date: | 2012-11-16 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
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4I88
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![BU of 4i88 by Molmil](/molmil-images/mine/4i88) | R107G HSP16.5 | Descriptor: | Small heat shock protein HSP16.5 | Authors: | Pohl, E, Williamson, I.R, Quinlan, R.A. | Deposit date: | 2012-12-03 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Changes in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the alpha-crystallin domain. PHILOS.TRANS.R.SOC.LOND.B BIOL.SCI., 368, 2013
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4I09
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![BU of 4i09 by Molmil](/molmil-images/mine/4i09) | structure of the mutant Catabolite gene activator protein V132L | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. | Deposit date: | 2012-11-16 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. Plos Biol., 11, 2013
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7ODM
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![BU of 7odm by Molmil](/molmil-images/mine/7odm) | AmGSTF1 Y118S variant | Descriptor: | Glutathione transferase, [(2~{S})-5-[[(2~{R})-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-3-sulfanyl-propan-2-yl]amino]-1-oxidanyl-1,5-bis(oxidanylidene)pentan-2-yl]azanium | Authors: | Pohl, E, Eno, R.F.M. | Deposit date: | 2021-04-30 | Release date: | 2022-04-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance. Org.Biomol.Chem., 19, 2021
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1BI0
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![BU of 1bi0 by Molmil](/molmil-images/mine/1bi0) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Hol, W.G. | Deposit date: | 1998-06-21 | Release date: | 1999-07-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1BI1
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![BU of 1bi1 by Molmil](/molmil-images/mine/1bi1) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1BI3
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![BU of 1bi3 by Molmil](/molmil-images/mine/1bi3) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1C0W
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![BU of 1c0w by Molmil](/molmil-images/mine/1c0w) | CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN | Descriptor: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), ... | Authors: | Pohl, E, Holmes, R.K, Hol, W.G. | Deposit date: | 1999-07-22 | Release date: | 2000-07-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. J.Mol.Biol., 292, 1999
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1B1B
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![BU of 1b1b by Molmil](/molmil-images/mine/1b1b) | IRON DEPENDENT REGULATOR | Descriptor: | PROTEIN (IRON DEPENDENT REGULATOR), SULFATE ION, ZINC ION | Authors: | Pohl, E, Holmes, R.K, Hol, W.G. | Deposit date: | 1998-11-19 | Release date: | 1999-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied. J.Mol.Biol., 285, 1999
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1BI2
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![BU of 1bi2 by Molmil](/molmil-images/mine/1bi2) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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7Z3M
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![BU of 7z3m by Molmil](/molmil-images/mine/7z3m) | |
1W8S
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![BU of 1w8s by Molmil](/molmil-images/mine/1w8s) | The mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase: Structural analysis of reaction intermediates | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I | Authors: | Lorentzen, E, Hensel, R, Siebers, B, Pohl, E. | Deposit date: | 2004-09-27 | Release date: | 2005-03-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates. Biochemistry, 44, 2005
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6IA5
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![BU of 6ia5 by Molmil](/molmil-images/mine/6ia5) | Crystal Structure Analysis of Bacillus subtilis 168 XepA | Descriptor: | ACETATE ION, GLYCEROL, Phage-like element PBSX protein XepA | Authors: | Freitag-Pohl, S, Pohl, E. | Deposit date: | 2018-11-26 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS. Acta Crystallogr D Struct Biol, 75, 2019
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2R91
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![BU of 2r91 by Molmil](/molmil-images/mine/2r91) | Crystal Structure of KD(P)GA from T.tenax | Descriptor: | 2-Keto-3-deoxy-(6-phospho-)gluconate aldolase, SULFATE ION | Authors: | Pauluhn, A, Pohl, E, Lorentzen, E, Siebers, B, Ahmed, H, Buchinger, S, Schomburg, D. | Deposit date: | 2007-09-12 | Release date: | 2008-03-18 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins, 72, 2008
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3MBU
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![BU of 3mbu by Molmil](/molmil-images/mine/3mbu) | Structure of a bipyridine-modified PNA duplex | Descriptor: | 1,2-ETHANEDIOL, Bipyridine-PNA, CARBONATE ION, ... | Authors: | Yeh, J.I, Pohl, E, Truan, D, He, W, Sheldrick, G.M, Du, S, Achim, C. | Deposit date: | 2010-03-26 | Release date: | 2011-03-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | The crystal structure of non-modified and bipyridine-modified PNA duplexes. Chemistry, 16, 2010
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2R94
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![BU of 2r94 by Molmil](/molmil-images/mine/2r94) | Crystal Structure of KD(P)GA from T.tenax | Descriptor: | 2-Keto-3-deoxy-(6-phospho-)gluconate aldolase, PYRUVIC ACID | Authors: | Pauluhn, A, Pohl, E. | Deposit date: | 2007-09-12 | Release date: | 2008-03-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins, 72, 2008
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4WGF
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![BU of 4wgf by Molmil](/molmil-images/mine/4wgf) | YcaC from Pseudomonas aeruginosa with hexane-2,5-diol and covalent acrylamide | Descriptor: | (2R,5R)-hexane-2,5-diol, CHLORIDE ION, PROPIONAMIDE, ... | Authors: | Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E. | Deposit date: | 2014-09-18 | Release date: | 2015-07-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.34020686 Å) | Cite: | Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct. Int J Mol Sci, 16, 2015
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7B3N
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![BU of 7b3n by Molmil](/molmil-images/mine/7b3n) | AmiP amidase-3 from Thermus parvatiensis | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Cell wall hydrolase, ... | Authors: | Freitag-Pohl, S, Pohl, E. | Deposit date: | 2020-12-01 | Release date: | 2022-06-22 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.793 Å) | Cite: | AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase. Protein Sci., 32, 2023
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7PJO
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![BU of 7pjo by Molmil](/molmil-images/mine/7pjo) | |
5FMN
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![BU of 5fmn by Molmil](/molmil-images/mine/5fmn) | |
2YCE
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![BU of 2yce by Molmil](/molmil-images/mine/2yce) | Structure of an Archaeal fructose-1,6-bisphosphate aldolase with the catalytic Lys covalently bound to the carbinolamine intermediate of the substrate. | Descriptor: | D-MANNITOL-1,6-DIPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1 | Authors: | Lorentzen, E, Siebers, B, Hensel, R, Pohl, E. | Deposit date: | 2011-03-14 | Release date: | 2011-04-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Mechanism of the Schiff Base Forming Fructose-1,6-Bisphosphate Aldolase: Structural Analysis of Reaction Intermediates. Biochemistry, 44, 2005
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8B9Y
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![BU of 8b9y by Molmil](/molmil-images/mine/8b9y) | Cysteine Synthase from Trypanosoma cruzi with PLP and OAS | Descriptor: | Cysteine synthase, putative, GLYCEROL, ... | Authors: | Sowerby, K.V, Pohl, E. | Deposit date: | 2022-10-10 | Release date: | 2023-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79, 2023
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8B9W
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![BU of 8b9w by Molmil](/molmil-images/mine/8b9w) | Cysteine Synthase from Trypanosoma theileri with PLP bound | Descriptor: | CHLORIDE ION, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Sowerby, K.V, Pohl, E. | Deposit date: | 2022-10-10 | Release date: | 2023-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79, 2023
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8B9M
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![BU of 8b9m by Molmil](/molmil-images/mine/8b9m) | Cysteine Synthase from Leishmania Infantum | Descriptor: | CHLORIDE ION, Cysteine synthase, GLYCEROL | Authors: | Sowerby, K.V, Pohl, E. | Deposit date: | 2022-10-06 | Release date: | 2023-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. Acta Crystallogr D Struct Biol, 79, 2023
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