6Q5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6q5t by Molmil](/molmil-images/mine/6q5t) | |
7ZPF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zpf by Molmil](/molmil-images/mine/7zpf) | Three-dimensional structure of AIP56, a short-trip single chain AB toxin from Photobacterium damselae subsp. piscicida. | Descriptor: | Aip56, GLYCEROL, NICKEL (II) ION, ... | Authors: | Lisboa, J, Pereira, P.J.B, dos Santos, N.M.S. | Deposit date: | 2022-04-27 | Release date: | 2023-05-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Unconventional structure and mechanisms for membrane interaction and translocation of the NF-kappa B-targeting toxin AIP56. Nat Commun, 14, 2023
|
|
7NZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nzz by Molmil](/molmil-images/mine/7nzz) | |
6FGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fgm by Molmil](/molmil-images/mine/6fgm) | The NMR solution structure of the peptide AC12 from Hypsiboas raniceps | Descriptor: | ALA-CYS-PHE-LEU-THR-ARG-LEU-GLY-THR-TYR-VAL-CYS | Authors: | Popov, C.S.F.C, Simas, B.S, Goodfellow, B.J, Bocca, A.L, Andrade, P.B, Pereira, D, Valentao, P, Pereira, P.J.B, Rodrigues, J.E, Veloso Jr, P.H.H, Rezende, T.M.B. | Deposit date: | 2018-01-11 | Release date: | 2019-01-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Host-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion. Peptides, 113, 2019
|
|
1TT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tt6 by Molmil](/molmil-images/mine/1tt6) | The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol | Descriptor: | DIETHYLSTILBESTROL, GLYCEROL, SULFATE ION, ... | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-06-22 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
|
|
1TZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tz8 by Molmil](/molmil-images/mine/1tz8) | The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol | Descriptor: | ACETATE ION, CARBONATE ION, DIETHYLSTILBESTROL, ... | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-07-09 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
|
|
3KIA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kia by Molmil](/molmil-images/mine/3kia) | Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus | Descriptor: | CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | Deposit date: | 2009-11-01 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity Mol.Microbiol., 79, 2011
|
|
3F1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f1y by Molmil](/molmil-images/mine/3f1y) | Mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Mannosyl-3-phosphoglycerate synthase | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | Deposit date: | 2008-10-28 | Release date: | 2009-11-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity Mol.Microbiol., 79, 2011
|
|
5DAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dae by Molmil](/molmil-images/mine/5dae) | |
2JB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jb9 by Molmil](/molmil-images/mine/2jb9) | PhoB response regulator receiver domain constitutively-active double mutant D10A and D53E. | Descriptor: | PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | Authors: | Ferrer-Orta, C, Arribas-Bosacoma, R, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M. | Deposit date: | 2006-12-05 | Release date: | 2007-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The X-Ray Crystal Structures of Two Constitutively Active Mutants of the E. Coli Phob Receiver Domain Give Insights Into Activation J.Mol.Biol., 366, 2007
|
|
2JBA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jba by Molmil](/molmil-images/mine/2jba) | PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION | Authors: | Arribas-Bosacoma, R, Ferrer-Orta, C, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M. | Deposit date: | 2006-12-05 | Release date: | 2007-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation. J.Mol.Biol., 366, 2007
|
|
6HWJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hwj by Molmil](/molmil-images/mine/6hwj) | Glucosamine kinase (crystal form A) | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Manso, J.A, Pereira, P.J.B. | Deposit date: | 2018-10-12 | Release date: | 2019-05-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.979 Å) | Cite: | Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity. Mbio, 10, 2019
|
|
6HWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hwk by Molmil](/molmil-images/mine/6hwk) | Glucosamine kinase (crystal form B) | Descriptor: | CHLORIDE ION, Glucosamine kinase, MAGNESIUM ION | Authors: | Manso, J.A, Pereira, P.J.B. | Deposit date: | 2018-10-12 | Release date: | 2019-05-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.688 Å) | Cite: | Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity. Mbio, 10, 2019
|
|
6HWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hwl by Molmil](/molmil-images/mine/6hwl) | Glucosamine kinase in complex with glucosamine, ADP and inorganic phosphate | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Manso, J.A, Pereira, P.J.B. | Deposit date: | 2018-10-12 | Release date: | 2019-05-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.148 Å) | Cite: | Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity. Mbio, 10, 2019
|
|
6G3N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g3n by Molmil](/molmil-images/mine/6g3n) | |
5L6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l6n by Molmil](/molmil-images/mine/5l6n) | Disulfated madanin-thrombin complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin, SODIUM ION, ... | Authors: | Ripoll-Rozada, J, Pereira, P.J.B. | Deposit date: | 2016-05-30 | Release date: | 2017-03-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.627 Å) | Cite: | Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors. Nat Chem, 9, 2017
|
|
5OOG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5oog by Molmil](/molmil-images/mine/5oog) | Human biliverdin IX beta reductase: NADP/Phloxine B ternary complex | Descriptor: | Flavin reductase (NADPH), GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Manso, J.A, Pereira, P.J.B. | Deposit date: | 2017-08-07 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | In silicoand crystallographic studies identify key structural features of biliverdin IX beta reductase inhibitors having nanomolar potency. J. Biol. Chem., 293, 2018
|
|
5OO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5oo2 by Molmil](/molmil-images/mine/5oo2) | Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with glucosylglycolate | Descriptor: | (alpha-D-glucopyranosyloxy)acetic acid, GLYCEROL, SERINE, ... | Authors: | Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B. | Deposit date: | 2017-08-05 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation. Iucrj, 6, 2019
|
|
5ONZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5onz by Molmil](/molmil-images/mine/5onz) | Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with glucosylglycolate | Descriptor: | (alpha-D-glucopyranosyloxy)acetic acid, GLYCEROL, Hydrolase, ... | Authors: | Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B. | Deposit date: | 2017-08-04 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation. Iucrj, 6, 2019
|
|
5ONT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ont by Molmil](/molmil-images/mine/5ont) | Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase(MhGgH) E419A variant in complex with glucosylglycerol | Descriptor: | 1,3-dihydroxypropan-2-yl alpha-D-glucopyranoside, GLYCEROL, Uncharacterized protein | Authors: | Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B. | Deposit date: | 2017-08-04 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation. Iucrj, 6, 2019
|
|
5OOH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ooh by Molmil](/molmil-images/mine/5ooh) | |
4IS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4is4 by Molmil](/molmil-images/mine/4is4) | |
4WZY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wzy by Molmil](/molmil-images/mine/4wzy) | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (ATP complex) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltokinase | Authors: | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | Deposit date: | 2014-11-20 | Release date: | 2015-02-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway. Sci Rep, 5, 2015
|
|
2ODY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ody by Molmil](/molmil-images/mine/2ody) | Thrombin-bound boophilin displays a functional and accessible reactive-site loop | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Boophilin, PHOSPHATE ION, ... | Authors: | Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | Deposit date: | 2006-12-27 | Release date: | 2008-01-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick. Plos One, 3, 2008
|
|
1X7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x7s by Molmil](/molmil-images/mine/1x7s) | The X-ray crystallographic structure of the amyloidogenic variant TTR Tyr78Phe | Descriptor: | Transthyretin | Authors: | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-08-16 | Release date: | 2005-03-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr.,Sect.D, 61, 2005
|
|