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PDB: 3 results

3EJ1
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BU of 3ej1 by Molmil
CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor
Descriptor: Cell division protein kinase 2, Cyclin-A2, N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine
Authors:Stevens, K, Reno, M, Alberti, J, Price, D, Kane-Carson, L, Knick, V, Shewchuk, L, Hassell, A, Veal, J, Peel, M.
Deposit date:2008-09-17
Release date:2008-10-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3EID
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BU of 3eid by Molmil
CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor
Descriptor: (2S)-1-(dimethylamino)-3-(4-{[4-(6-morpholin-4-ylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol, Cell division protein kinase 2, Cyclin-A2
Authors:Steven, K, Reno, M, Alberti, J, Price, D, Kane-Carson, L, Knick, V, Shewchuk, L, Hassell, A, Veal, J, Peel, M.
Deposit date:2008-09-15
Release date:2008-10-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1QMO
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BU of 1qmo by Molmil
Structure of FRIL, a legume lectin that delays hematopoietic progenitor maturation
Descriptor: CALCIUM ION, MANGANESE (II) ION, MANNOSE BINDING LECTIN, ...
Authors:Hamelryck, T.W, Moore, J.G, Chrispeels, M, Loris, R, Wyns, L.
Deposit date:1999-10-04
Release date:1999-10-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The Role of Weak Protein-Protein Interactions in Multivalent Lectin-Carbohydrate Binding: Crystal Structure of Cross-Linked Fril
J.Mol.Biol., 299, 2000

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