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PDB: 59 results

6NRH
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BU of 6nrh by Molmil
Crystal Structure of human PARP-1 ART domain bound inhibitor UTT63
Descriptor: 3-hydroxy-2-({4-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ...
Authors:Langelier, M.F, Pascal, J.M.
Deposit date:2019-01-23
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.
J.Med.Chem., 62, 2019
1OBT
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BU of 1obt by Molmil
STRUCTURE OF RICIN A CHAIN MUTANT, COMPLEX WITH AMP
Descriptor: ADENOSINE MONOPHOSPHATE, RICIN A CHAIN
Authors:Day, P.J, Ernst, S.R, Frankel, A.E, Monzingo, A.F, Pascal, J.M, Svinth, M, Robertus, J.D.
Deposit date:1996-06-22
Release date:1997-06-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and activity of an active site substitution of ricin A chain.
Biochemistry, 35, 1996
1OBS
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BU of 1obs by Molmil
STRUCTURE OF RICIN A CHAIN MUTANT
Descriptor: RICIN A CHAIN
Authors:Day, P.J, Ernst, S.R, Frankel, A.E, Monzingo, A.F, Pascal, J.M, Svinth, M, Robertus, J.D.
Deposit date:1996-06-25
Release date:1997-06-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and activity of an active site substitution of ricin A chain.
Biochemistry, 35, 1996
6VKQ
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BU of 6vkq by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor EB-47
Descriptor: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION
Authors:Steffen, J.D, Pascal, J.M.
Deposit date:2020-01-21
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
6VKK
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BU of 6vkk by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor rucaparib
Descriptor: GLYCEROL, Poly [ADP-ribose] polymerase 1, Rucaparib, ...
Authors:Steffen, J.D, Pascal, J.M.
Deposit date:2020-01-21
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
6VKO
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BU of 6vko by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor UKTT15
Descriptor: Poly [ADP-ribose] polymerase 1, SULFATE ION, methyl 2-{4-[4-(7-carbamoyl-1H-benzimidazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}pyrimidine-5-carboxylate
Authors:Langelier, M.F, Pascal, J.M.
Deposit date:2020-01-21
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
7RPX
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BU of 7rpx by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA
Descriptor: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ...
Authors:Sverzhinsky, A, Pascal, J.M.
Deposit date:2021-08-04
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
7RPO
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BU of 7rpo by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ...
Authors:Sverzhinsky, A, Pascal, J.M.
Deposit date:2021-08-03
Release date:2021-11-17
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
7RPW
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BU of 7rpw by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ...
Authors:Sverzhinsky, A, Pascal, J.M.
Deposit date:2021-08-04
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.38 Å)
Cite:Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
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數據於2024-06-12公開中

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