2O2F
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![BU of 2o2f by Molmil](/molmil-images/mine/2o2f) | Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand | Descriptor: | 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-2 | Authors: | Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. | Deposit date: | 2006-11-29 | Release date: | 2007-02-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
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2O21
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![BU of 2o21 by Molmil](/molmil-images/mine/2o21) | Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand | Descriptor: | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2 | Authors: | Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. | Deposit date: | 2006-11-29 | Release date: | 2007-02-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
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4OGF
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![BU of 4ogf by Molmil](/molmil-images/mine/4ogf) | |
4OQ6
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![BU of 4oq6 by Molmil](/molmil-images/mine/4oq6) | Crystal Structure of Human MCL-1 Bound to Inhibitor 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid | Descriptor: | 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Petros, A.M, Swann, S.L, Song, D, Swinger, K, Park, C, Zhang, H, Wendt, M.D, Kunzer, A.R, Souers, A.J, Sun, C. | Deposit date: | 2014-02-07 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg.Med.Chem.Lett., 24, 2014
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1PIB
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![BU of 1pib by Molmil](/molmil-images/mine/1pib) | Solution structure of DNA containing CPD opposited by GA | Descriptor: | 5'-D(*CP*GP*CP*AP*TP*TP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*GP*AP*TP*GP*CP*G)-3' | Authors: | Lee, J.H, Park, C.J, Shin, J.S, Choi, B.S. | Deposit date: | 2003-05-30 | Release date: | 2004-05-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structure of the DNA decamer duplex containing double T*G mismatches of cis-syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC-hHR23B complex. Nucleic Acids Res., 32, 2004
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7XX9
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![BU of 7xx9 by Molmil](/molmil-images/mine/7xx9) | |
7XX8
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![BU of 7xx8 by Molmil](/molmil-images/mine/7xx8) | |
1SNH
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![BU of 1snh by Molmil](/molmil-images/mine/1snh) | Solution structure of the DNA Decamer Duplex Containing Double TG Mismatches of Cis-syn Cyclobutane Pyrimidine Dimer | Descriptor: | 5'-D(*CP*GP*CP*AP*TP*TP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*GP*GP*TP*GP*CP*G)-3' | Authors: | Lee, J.H, Park, C.J, Shin, J.S, Ikegami, T, Akutsu, H, Choi, B.S. | Deposit date: | 2004-03-11 | Release date: | 2004-05-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structure of the DNA decamer duplex containing double T*G mismatches of cis-syn cyclobutane pyrimidine dimer: implications for DNA damage recognition by the XPC-hHR23B complex. Nucleic Acids Res., 32, 2004
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2XTX
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![BU of 2xtx by Molmil](/molmil-images/mine/2xtx) | Structure of QnrB1 (M102R-Trypsin Treated), a plasmid-mediated fluoroquinolone resistance protein | Descriptor: | QNRB1, SULFATE ION | Authors: | Vetting, M.W, Hegde, S.S, Park, C.H, Jacoby, G.A, Hooper, D.C, Blanchard, J.S. | Deposit date: | 2010-10-12 | Release date: | 2010-10-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Qnrb1, a Plasmid-Mediated Fluoroquinolone Resistance Factor. J.Biol.Chem., 286, 2011
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2XTY
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![BU of 2xty by Molmil](/molmil-images/mine/2xty) | Structure of QnrB1 (R167E-Trypsin Treated), a plasmid-mediated fluoroquinolone resistance protein | Descriptor: | QNRB1 | Authors: | Vetting, M.W, Hegde, S.S, Park, C.H, Jacoby, G.A, Hooper, D.C, Blanchard, J.S. | Deposit date: | 2010-10-13 | Release date: | 2010-10-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Qnrb1, a Plasmid-Mediated Fluoroquinolone Resistance Factor. J.Biol.Chem., 286, 2011
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2XTW
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![BU of 2xtw by Molmil](/molmil-images/mine/2xtw) | Structure of QnrB1 (Full length), a plasmid-mediated fluoroquinolone resistance protein | Descriptor: | QNRB1 | Authors: | Vetting, M.W, Hegde, S.S, Park, C.H, Jacoby, G.A, Hooper, D.C, Blanchard, J.S. | Deposit date: | 2010-10-12 | Release date: | 2010-10-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Structure of Qnrb1, a Plasmid-Mediated Fluoroquinolone Resistance Factor. J.Biol.Chem., 286, 2011
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1LF7
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![BU of 1lf7 by Molmil](/molmil-images/mine/1lf7) | Crystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution | Descriptor: | CITRIC ACID, Complement Protein C8gamma | Authors: | Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L. | Deposit date: | 2002-04-10 | Release date: | 2002-06-12 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site. Biochemistry, 41, 2002
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1IW2
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![BU of 1iw2 by Molmil](/molmil-images/mine/1iw2) | X-ray structure of Human Complement Protein C8gamma at pH=7.O | Descriptor: | Complement Protein C8gamma | Authors: | Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L. | Deposit date: | 2002-04-11 | Release date: | 2002-06-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site. Biochemistry, 41, 2002
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4ZHI
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![BU of 4zhi by Molmil](/molmil-images/mine/4zhi) | |