6P8M
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6WT3
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![BU of 6wt3 by Molmil](/molmil-images/mine/6wt3) | Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase | Descriptor: | 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN | Authors: | Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M. | Deposit date: | 2020-05-01 | Release date: | 2020-07-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase. J.Lipid Res., 61, 2020
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6WN4
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![BU of 6wn4 by Molmil](/molmil-images/mine/6wn4) | Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase | Descriptor: | 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide | Authors: | Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M. | Deposit date: | 2020-04-22 | Release date: | 2020-07-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase. J.Lipid Res., 61, 2020
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6VLW
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![BU of 6vlw by Molmil](/molmil-images/mine/6vlw) | Crystal Structure of 426cOD in Complex with VRC01 Fab | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 426cOD, ... | Authors: | Weidle, C, Pancera, M. | Deposit date: | 2020-01-27 | Release date: | 2020-12-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors. Immunity, 53, 2020
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7RQQ
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7RQP
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![BU of 7rqp by Molmil](/molmil-images/mine/7rqp) | Structure of PfCSP NPNV binding antibody L9 | Descriptor: | L9 Heavy Chain, L9 Kappa Chain | Authors: | Hurlburt, N.K, Pancera, M. | Deposit date: | 2021-08-06 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38, 2022
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7RQR
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1GPZ
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![BU of 1gpz by Molmil](/molmil-images/mine/1gpz) | THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1R COMPONENT, ... | Authors: | Budayova-Spano, M, Fontecilla-Camps, J.C, Gaboriaud, C. | Deposit date: | 2001-11-15 | Release date: | 2002-07-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Crystal Structure of the Zymogen Catalytic Domain of Complement Protease C1R Reveals that a Disruptive Mechanical Stress is Required to Trigger Activation of the C1 Complex. Embo J., 21, 2002
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6U9U
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![BU of 6u9u by Molmil](/molmil-images/mine/6u9u) | Structure of GM9_TH8seq732127 FAB | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ... | Authors: | Singh, S, Liban, T.J, Pancera, M. | Deposit date: | 2019-09-09 | Release date: | 2019-11-06 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
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6XQW
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![BU of 6xqw by Molmil](/molmil-images/mine/6xqw) | Crystal Structure of MaliM03 Fab in complex with Pfmsp1-19 | Descriptor: | MaliM03 Fab Heavy Chain, MaliM03 Fab Light Chain, Pfmsp1-19 | Authors: | Singh, S, Pancera, M. | Deposit date: | 2020-07-10 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.991 Å) | Cite: | Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites. J.Exp.Med., 218, 2021
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6OL6
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![BU of 6ol6 by Molmil](/molmil-images/mine/6ol6) | Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab | Descriptor: | CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ... | Authors: | Weidle, C, Pancera, M, Gewe, M. | Deposit date: | 2019-04-15 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes. J.Exp.Med., 216, 2019
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6MYY
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![BU of 6myy by Molmil](/molmil-images/mine/6myy) | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | Authors: | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | Deposit date: | 2018-11-02 | Release date: | 2018-11-14 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
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6MZJ
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![BU of 6mzj by Molmil](/molmil-images/mine/6mzj) | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | Authors: | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | Deposit date: | 2018-11-05 | Release date: | 2018-11-14 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife, 7, 2018
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8VRU
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![BU of 8vru by Molmil](/molmil-images/mine/8vru) | GII.4c apo norovirus protruding domain | Descriptor: | 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID | Authors: | Kher, G, Prewitt, A, Pancera, M, Hansman, G. | Deposit date: | 2024-01-22 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Advancement of norovirus therapies To Be Published
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8Y6C
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![BU of 8y6c by Molmil](/molmil-images/mine/8y6c) | Norovirus GII.10 P domain and 2'-FL (powder) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GII.10 norovirus P domain in complex with 2'FL (powder), ... | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | Deposit date: | 2024-02-02 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Norovirus GII.10 P domain and 2'-FL (powder) To Be Published
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8VRV
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![BU of 8vrv by Molmil](/molmil-images/mine/8vrv) | GII.4c H2-tri HBGA norovirus protruding domain | Descriptor: | 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID, ... | Authors: | Kher, G, Prewitt, A, Pancera, M, Hansman, G. | Deposit date: | 2024-01-22 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Advancement of norovirus therapies To Be Published
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7ELL
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![BU of 7ell by Molmil](/molmil-images/mine/7ell) | |
7ELH
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1MD7
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![BU of 1md7 by Molmil](/molmil-images/mine/1md7) | Monomeric structure of the zymogen of complement protease C1r | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C1R COMPLEMENT SERINE PROTEASE | Authors: | Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2002-08-07 | Release date: | 2003-08-07 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10, 2002
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1MD8
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![BU of 1md8 by Molmil](/molmil-images/mine/1md8) | Monomeric structure of the active catalytic domain of complement protease C1r | Descriptor: | C1R COMPLEMENT SERINE PROTEASE | Authors: | Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C. | Deposit date: | 2002-08-07 | Release date: | 2003-08-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10, 2002
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3M4X
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6VJN
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![BU of 6vjn by Molmil](/molmil-images/mine/6vjn) | Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide | Descriptor: | D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ... | Authors: | Singh, S, Liban, T.J, Pancera, M. | Deposit date: | 2020-01-16 | Release date: | 2021-01-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6VRQ
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![BU of 6vrq by Molmil](/molmil-images/mine/6vrq) | Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Aljedani, S.S, Weidle, C, Pancera, M. | Deposit date: | 2020-02-08 | Release date: | 2021-02-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies. Cell Rep, 35, 2021
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6WAS
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![BU of 6was by Molmil](/molmil-images/mine/6was) | Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold | Descriptor: | 1FD6 16055 V1V2 scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, GN1_PA8 Fab Heavy chain, ... | Authors: | Singh, S, Liban, T.J, Pancera, M. | Deposit date: | 2020-03-26 | Release date: | 2021-03-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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6WIT
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![BU of 6wit by Molmil](/molmil-images/mine/6wit) | Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold | Descriptor: | 16055 V1V2 1FD6 Scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, NHP GN1-SD7 Fab Heavy Chain, ... | Authors: | Liban, T, Aljedani, S, Rodarte, J, Pancera, M. | Deposit date: | 2020-04-10 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathog., 17, 2021
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