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PDB: 45910 件

7XQM
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InDel-mutant short chain Dehydrogenase bound to SAH
分子名称: Dehydrogenase, S-ADENOSYL-L-HOMOCYSTEINE
著者Toledo-Patino, S, Laurino, P.
登録日2022-05-08
公開日2022-12-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Insertions and deletions mediated functional divergence of Rossmann fold enzymes.
Proc.Natl.Acad.Sci.USA, 119, 2022
1NHM
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THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
分子名称: HIGH MOBILITY GROUP PROTEIN 1
著者Read, C.M, Cary, P.D, Crane-Robinson, C, Driscoll, P.C, Carillo, M.O.M, Norman, D.G.
登録日1994-11-17
公開日1995-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Structure of the Hmg Box and its Interaction with DNA
NUCLEIC ACIDS MOL.BIOL., 9, 1995
4M5A
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Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina inhibited by asymmetric dimethyl arginine at 1.70 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NG,NG-DIMETHYL-L-ARGININE, rRNA N-glycosidase
著者Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P.
登録日2013-08-08
公開日2013-08-28
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina inhibited by asymmetric dimethyl arginine at 1.70 A resolution
To be Published
3GR9
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Crystal structure of ColD H188K S187N
分子名称: 2-OXOGLUTARIC ACID, ColD
著者Holden, H.M, Cook, P.D, Kubiak, R.L, Toomey, D.P.
登録日2009-03-25
公開日2009-06-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Two Site-Directed Mutations Are Required for the Conversion of a Sugar Dehydratase into an Aminotransferase.
Biochemistry, 48, 2009
1JDL
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Structure of cytochrome c2 from Rhodospirillum Centenum
分子名称: CYTOCHROME C2, ISO-2, PROTOPORPHYRIN IX CONTAINING FE
著者Camara-Artigas, A, Williams, J.C, Allen, J.P.
登録日2001-06-14
公開日2001-11-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of cytochrome c2 from Rhodospirillum centenum.
Acta Crystallogr.,Sect.D, 57, 2001
2H7C
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Crystal structure of human carboxylesterase in complex with Coenzyme A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, ...
著者Bencharit, S, Edwards, C.C, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R.
登録日2006-06-02
公開日2006-08-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
J.Mol.Biol., 363, 2006
5C23
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Parkin (S65DUblR0RBR)
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
著者Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
2H0Y
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Crystal structure of the M69V E166A double mutant of SHV-1 b-lactamase complexed to sulbactam
分子名称: Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ETHANESULFONIC ACID, ...
著者van den Akker, F, Padayatti, P.S.
登録日2006-05-15
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
Biochemistry, 45, 2006
2HA0
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Crystal structure of mouse acetylcholinesterase complexed with 4-ketoamyltrimethylammonium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, Acetylcholinesterase, ...
著者Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P.
登録日2006-06-12
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding
J.Biol.Chem., 281, 2006
3QS0
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Crystal structure of the complex of peptidoglycan recognition protein (PGRP-S) with a bound N-acetylglucosamine in the diffusion channel at 2.5 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, L(+)-TARTARIC ACID, ...
著者Dube, D, Sharma, P, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2011-02-19
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the complex of peptidoglycan recognition protein (PGRP-S) with a bound N-acetylglucosamine in the diffusion channel AT 2.5 A resolution
To be Published
2XUP
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CRYSTAL STRUCTURE OF the MACHE-Y337A mutant in complex with soaked TZ2PA6 SYN inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-5-YL]HEXYL]-PHENANTHRIDINIUM, ACETYLCHOLINESTERASE, ...
著者Bourne, Y, Radic, Z, Taylor, P, Marchot, P.
登録日2010-10-19
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State
J.Am.Chem.Soc., 132, 2010
5C7R
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Revealing surface waters on an antifreeze protein by fusion protein crystallography
分子名称: Fusion protein of Maltose-binding periplasmic protein and Type-3 ice-structuring protein HPLC 12, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Sun, T, Gauthier, S, Campbell, R.L, Davies, P.L.
登録日2015-06-24
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Revealing Surface Waters on an Antifreeze Protein by Fusion Protein Crystallography Combined with Molecular Dynamic Simulations.
J.Phys.Chem.B, 119, 2015
1TOS
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TORPEDO CALIFORNICA ACHR RECEPTOR [ALA76] ANALOGUE COMPLEXED WITH THE ANTI-ACETYLCHOLINE MAB6 MONOCLONAL ANTIBODY
分子名称: ACETYLCHOLINE RECEPTOR [ALA76] MIR ANALOGUE
著者Orlewski, P, Tsikaris, V, Sakarellos, C, Sakarellos-Daistiotis, M, Vatzaki, E, Tzartos, S.J, Marraud, M, Cung, M.T.
登録日1995-10-11
公開日1996-03-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76]MIR analogue: a molecular dynamics simulation from two-dimensional NMR data.
Biopolymers, 40, 1996
3PG9
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Thermotoga maritima DAH7P synthase in complex with inhibitor
分子名称: AZIDE ION, CHLORIDE ION, NITRATE ION, ...
著者Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J.
登録日2010-10-31
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
1TP9
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PRX D (type II) from Populus tremula
分子名称: SULFATE ION, peroxiredoxin
著者Echalier, A, Trivelli, X, Corbier, C, Rouhier, N, Walker, O, Tsan, P, Jacquot, J.P, Krimm, I, Lancelin, J.M.
登録日2004-06-16
公開日2005-04-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism
Biochemistry, 44, 2005
2H5S
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SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase
分子名称: (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, SHV-1 beta-lactamase
著者van den Akker, F, Padayatti, P.S.
登録日2006-05-27
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Rational Design of a beta-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate: 1.28 A Crystal Structure of wt SHV-1 Complex with a Penam Sulfone.
J.Am.Chem.Soc., 128, 2006
2Y02
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TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND AGONIST CARMOTEROL
分子名称: BETA-1 ADRENERGIC RECEPTOR, CARMOTEROL, CHOLESTEROL HEMISUCCINATE, ...
著者Warne, A, Moukhametzianov, R, Baker, J.G, Nehme, R, Edwards, P.C, Leslie, A.G.W, Schertler, G.F.X, Tate, C.G.
登録日2010-11-30
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structural Basis for Agonist and Partial Agonist Action on a Beta1-Adrenergic Receptor
Nature, 469, 2011
3LEY
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2F5 Epitope scaffold elicited anti-HIV-1 monoclonal antibody 6a7 in complex with HIV-1 GP41
分子名称: 6a7 Antibody Heavy Chain, 6a7 Antibody Light Chain, Envelope glycoprotein gp41, ...
著者Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
登録日2010-01-15
公開日2010-09-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PQV
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Cyclase homolog
分子名称: D(-)-TARTARIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Tanaka, N, Smith, P, Shuman, S.
登録日2010-11-27
公開日2011-04-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献Crystal structure of Rcl1, an essential component of the eukaryal pre-rRNA processosome implicated in 18s rRNA biogenesis.
Rna, 17, 2011
1TUT
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J4/5 Loop from the Candida albicans and Candida dubliniensis Group I Introns
分子名称: 5'-R(*GP*AP*GP*GP*AP*AP*GP*GP*CP*GP*A)-3', 5'-R(*UP*CP*GP*UP*UP*AP*AP*UP*CP*UP*C)-3'
著者Znosko, B.M, Kennedy, S.D, Wille, P.C, Krugh, T.R, Turner, D.H.
登録日2004-06-25
公開日2004-12-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Features and Thermodynamics of the J4/5 Loop from the Candida albicans and Candida dubliniensis Group I Introns.
Biochemistry, 43, 2004
5CAY
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Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 core from ST strain of HIV-2, ...
著者Davenport, Y.W, Bjorkman, P.J.
登録日2015-06-30
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
2XWT
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CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN, ...
著者Sanders, J, Sanders, P, Young, S, Kabelis, K, Baker, S, Sullivan, A, Evans, M, Clark, J, Wilmot, J, Hu, X, Roberts, E, Powell, M, Nunez Miguel, R, Furmaniak, J, Rees Smith, B.
登録日2010-11-05
公開日2011-03-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody.
J.Mol.Endocrinol., 46, 2011
1TU4
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Crystal Structure of Rab5-GDP Complex
分子名称: COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-5A, ...
著者Zhu, G, Zhai, P, Liu, J, Terzyan, S, Li, G, Zhang, X.C.
登録日2004-06-24
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of Rab5-Rabaptin5 interaction in endocytosis
Nat.Struct.Mol.Biol., 11, 2004
3LGQ
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Structure of the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase in complex with sulfite (modified Tyr-303)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Trofimov, A.A, Polyakov, K.M, Boyko, K.M, Filimonenkov, A.A, Tikhonova, T.V, Lamzin, V.S, Bourenkov, G.P, Popov, V.O.
登録日2010-01-21
公開日2011-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Covalent modifications of the catalytic tyrosine in octahaem cytochrome c nitrite reductase and their effect on the enzyme activity.
Acta Crystallogr.,Sect.D, 68, 2012
4AIL
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Crystal Structure of an Evolved Replicating DNA Polymerase
分子名称: 5'-D(*AP*CP*GP*GP*GP*TP*AP*AP*GP*CP*AP)-3', 5'-D(*TP*GP*CP*TP*TP*AP*CP*DOCP)-3', DNA POLYMERASE
著者Wynne, S.A, Holliger, P, Leslie, A.G.W.
登録日2012-02-10
公開日2012-03-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of an Apo and a Binary Complex of an Evolved Archeal B Family DNA Polymerase Capable of Synthesising Highly Cy-Dye Labelled DNA.
Plos One, 8, 2013

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