4FOR
 
 | | Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Flurbiprofen at 1.58 A Resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal peptide from Lactotransferrin, ... | | 著者 | Shukla, P.K, Gautam, L, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2012-06-21 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Flurbiprofen at 1.58 A Resolution
To be Published
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3UQV
 | | Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor | | 分子名称: | 3-(3-carbamimidoylphenyl)-N-(2'-sulfamoylbiphenyl-4-yl)-1,2-oxazole-4-carboxamide, CALCIUM ION, Cationic trypsin, ... | | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | | 登録日 | 2011-11-21 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
Biol.Chem., 395, 2014
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1URF
 | | HR1b domain from PRK1 | | 分子名称: | PROTEIN KINASE C-LIKE 1 | | 著者 | Owen, D, Lowe, P.N, Nietlispach, D, Brosnan, C.E, Chirgadze, D.Y, Parker, P.J, Blundell, T.L, Mott, H.R. | | 登録日 | 2003-10-29 | | 公開日 | 2003-11-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Dissection of the Interaction between the Small G Proteins Rac1 and Rhoa and Protein Kinase C-Related Kinase 1 (Prk1)
J.Biol.Chem., 278, 2003
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5D0K
 | | Structure of UbE2D2:RNF165:Ub complex | | 分子名称: | Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ... | | 著者 | Wright, J.D, Day, C.L, Mace, P.D. | | 登録日 | 2015-08-03 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
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1JF2
 | | Crystal Structure of W92F obelin mutant from Obelia longissima at 1.72 Angstrom resolution | | 分子名称: | C2-HYDROPEROXY-COELENTERAZINE, obelin | | 著者 | Liu, Z.-J, Vysotski, E.S, Deng, L, Markova, S.V, Lee, J, Rose, J.P, Wang, B.-C. | | 登録日 | 2001-06-19 | | 公開日 | 2001-07-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Violet bioluminescence and fast kinetics from W92F obelin: structure-based proposals for the bioluminescence triggering and the identification of the emitting species.
Biochemistry, 42, 2003
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4PS7
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3STR
 | | Strep Peptide Deformylase with a time dependent thiazolidine hydroxamic acid | | 分子名称: | (4R)-3-(4-[4-(2-chlorophenyl)piperazin-1-yl]-6-{[2-methyl-6-(methylcarbamoyl)phenyl]amino}-1,3,5-triazin-2-yl)-N-[2-(hydroxyamino)-2-oxoethyl]-1,3-thiazolidine-4-carboxamide, GLYCEROL, NICKEL (II) ION, ... | | 著者 | Campobasso, N, Ward, P. | | 登録日 | 2011-07-11 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.
Biochemistry, 50, 2011
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4DUU
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6F2Q
 | | Neutron crystal structure of perdeuterated galectin-3C in the ligand-free form | | 分子名称: | Galectin-3 | | 著者 | Manzoni, F, Blakeley, M.P, Oksanen, E, Logan, D.T. | | 登録日 | 2017-11-27 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | NEUTRON DIFFRACTION (1.03 Å), X-RAY DIFFRACTION | | 主引用文献 | Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design.
J. Med. Chem., 61, 2018
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1OBN
 | | ISOPENICILLIN N SYNTHASE aminoadipoyl-cysteinyl-aminobutyrate-FE-NO COMPLEX | | 分子名称: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-VINYLGLYCINE, FE (II) ION, HYDROXYAMINE, ... | | 著者 | Long, A.J, Clifton, I.J, Roach, P.L, Baldwin, J.E, Schofield, C.J, Rutledge, P.J. | | 登録日 | 2003-01-31 | | 公開日 | 2004-02-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural Studies on the Reaction of Isopenicillin N Synthase with the Substrate Analogue Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D-Alpha-Aminobutyrate.
Biochem.J., 372, 2003
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4DAV
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1OEZ
 | | Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase | | 分子名称: | SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION | | 著者 | Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Elam, J.S, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S. | | 登録日 | 2003-04-02 | | 公開日 | 2003-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Amyloid-Like Filaments and Water-Filled Nanotubes Formed by Sod1 Mutant Proteins Linked to Familial Als
Nat.Struct.Biol., 10, 2003
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4KW7
 | | The structure of an As(III) S-adenosylmethionine methyltransferase with Phenylarsine oxide(PAO) | | 分子名称: | Arsenic methyltransferase, CALCIUM ION, Phenylarsine oxide | | 著者 | Packianathan, C, Marapakala, K, Ajees, A.A, Kandavelu, P, Rosen, B.P. | | 登録日 | 2013-05-23 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A disulfide-bond cascade mechanism for arsenic(III) S-adenosylmethionine methyltransferase.
Acta Crystallogr.,Sect.D, 71, 2015
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3G2T
 | | VHS Domain of human GGA1 complexed with SorLA C-terminal Phosphopeptide | | 分子名称: | ADP-ribosylation factor-binding protein GGA1, IODIDE ION, Phosphorylated C-terminal fragment of Sortilin-related receptor | | 著者 | Cramer, J.F, Behrens, M.A, Gustafsen, C, Oliveira, C.L.P, Pedersen, J.S, Madsen, P, Petersen, C.M, Thirup, S.S. | | 登録日 | 2009-02-01 | | 公開日 | 2009-12-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | GGA autoinhibition revisited
Traffic, 11, 2010
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3UXE
 | | Design, Synthesis and Biological Evaluation of Potent Quinoline and Pyrroloquinoline Ammosamide Analogues as Inhibitors for Quinone Reductase 2 | | 分子名称: | 8-amino-7-chloro-1-methyl-6-(methylideneamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxamide, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Reddy, N.P, Jensen, K.C, Mesecar, A.D, Fanwick, P.E, Cushman, M. | | 登録日 | 2011-12-05 | | 公開日 | 2012-01-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent quinoline and pyrroloquinoline ammosamide analogues as inhibitors of quinone reductase 2.
J.Med.Chem., 55, 2012
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3NR8
 | | Crystal structure of human SHIP2 | | 分子名称: | CHLORIDE ION, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2010-06-30 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases
Structure, 22, 2014
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3JQJ
 | | Crystal structure of the molybdenum cofactor biosynthesis protein C (TTHA1789) from Thermus Theromophilus HB8 | | 分子名称: | GLYCEROL, Molybdenum cofactor biosynthesis protein C, PHOSPHATE ION, ... | | 著者 | Kanaujia, S.P, Jeyakanthan, J, Nakagawa, N, Sekar, K, Baba, S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2009-09-07 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of apo and GTP-bound molybdenum cofactor biosynthesis protein MoaC from Thermus thermophilus HB8
Acta Crystallogr.,Sect.D, 66, 2010
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2BDI
 | | Human Kallikrein 4 complex with cobalt and p-aminobenzamidine | | 分子名称: | COBALT (II) ION, Kallikrein-4, P-AMINO BENZAMIDINE | | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | | 登録日 | 2005-10-20 | | 公開日 | 2006-10-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
J.Mol.Biol., 362, 2006
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2JD8
 | | Crystal Structure of the Zn-soaked Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus furiosus | | 分子名称: | FE (III) ION, FERRITIN HOMOLOG, SULFATE ION, ... | | 著者 | Tatur, J, Hagen, W.R, Matias, P.M. | | 登録日 | 2007-01-05 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of the Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus Furiosus
J.Biol.Inorg.Chem., 12, 2007
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6FD5
 | | Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 14 days post crystallization (with AMP and PPi products partially generated) | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, ... | | 著者 | Nioche, P, Huyet, J, Ozeir, M. | | 登録日 | 2017-12-21 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
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4L0W
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4P94
 | | The crystal structure of the soluble domain of Sulfolobus acidocaldarius FlaF (residues 35-164) | | 分子名称: | Conserved flagellar protein F, SODIUM ION | | 著者 | Tsai, C.-L, Arvai, A.S, Ishida, J.P, Tainer, J.A. | | 登録日 | 2014-04-02 | | 公開日 | 2015-04-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | FlaF Is a beta-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein.
Structure, 23, 2015
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8D30
 | | Crystal structure of the human COPB2 WD-domains | | 分子名称: | 1,2-ETHANEDIOL, Coatomer subunit beta' | | 著者 | Zeng, H, Dong, A, Hutchinson, A, Seitova, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2022-05-31 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the human COPB2 WD-domains
To Be Published
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7W9G
 | | Complex structure of Mpro with ebselen-derivative inhibitor | | 分子名称: | 3C-like proteinase nsp5, SELENIUM ATOM | | 著者 | Sahoo, P, Kumar, A. | | 登録日 | 2021-12-09 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
Acs Pharmacol Transl Sci, 6, 2023
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5AF5
 | | Structure of Lys33-linked triUb S.G. P 212121 | | 分子名称: | POLYUBIQUITIN-C | | 著者 | Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D. | | 登録日 | 2015-01-19 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
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