7W9G

Complex structure of Mpro with ebselen-derivative inhibitor

Summary for 7W9G

• Entry DOI: 10.2210/pdb7w9g/pdb
• Descriptor: 3C-like proteinase nsp5, SELENIUM ATOM (3 entities in total)
• Functional Keywords: protease, cov-2, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 33991.58

Authors

Sahoo, P.,Kumar, A. (deposition date: 2021-12-09, release date: 2022-12-14, Last modification date: 2023-11-29)

• Primary citation: Sahoo, P.,Lenka, D.R.,Batabyal, M.,Pain, P.K.,Kumar, S.,Manna, D.,Kumar, A.; Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).; Acs Pharmacol Transl Sci, 6:171-180, 2023; PubMed: 36650888; DOI: 10.1021/acsptsci.2c00203

Experimental method

X-RAY DIFFRACTION (2.5 Å)