2I7A
 
 | | Domain IV of Human Calpain 13 | | 分子名称: | CALCIUM ION, Calpain 13, GLYCEROL, ... | | 著者 | Walker, J.R, Ng, K, Davis, T.L, Ravulapalli, R, Butler-cole, C, Finerty Jr, P.J, Newman, E.M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2006-08-30 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of Human Calpain 13
To be Published
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3GG2
 | | Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate | | 分子名称: | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Chang, S, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-02-27 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate
To be Published
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3GHH
 | | Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ecto-NAD+ glycohydrolase (CD38 molecule), SULFATE ION, ... | | 著者 | Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N.J, Kellenberger, E, Schuber, F. | | 登録日 | 2009-03-03 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates.
Plos One, 7, 2012
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7Q0V
 | | Lysozyme soaked with V(IV)OSO4 and phen | | 分子名称: | 1,10-PHENANTHROLINE, ACETATE ION, CHLORIDE ION, ... | | 著者 | Santos, M.F.A, Fernandes, A.C.P, Correia, I, Sciortino, G, Garribba, E, Santos-Silva, T, Pessoa, J.C. | | 登録日 | 2021-10-16 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Binding of V IV O 2+ , V IV OL, V IV OL 2 and V V O 2 L Moieties to Proteins: X-ray/Theoretical Characterization and Biological Implications.
Chemistry, 28, 2022
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4CB8
 | | Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin alpha | | 分子名称: | BETA-CATENIN-LIKE PROTEIN 1, SULFATE ION | | 著者 | Ganesh, K, vanMaldegem, F, Telerman, S.B, Simpson, P, Johnson, C.M, Williams, R.L, Neuberger, M.S, Rada, C. | | 登録日 | 2013-10-10 | | 公開日 | 2013-12-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Mutational Analysis Reveals that Ctnnbl1 Binds Nlss in a Manner Distinct from that of its Closest Armadillo-Relative, Karyopherin Alpha
FEBS Lett., 588, 2014
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1VKT
 | | HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES | | 分子名称: | INSULIN | | 著者 | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 1996-10-14 | | 公開日 | 1997-04-01 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264, 1996
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4BSR
 | | Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ... | | 著者 | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | | 登録日 | 2013-06-11 | | 公開日 | 2013-06-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
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4ZQI
 | | Crystal structure of Apo D-alanine-D-alanine ligase(DDL) from Yersinia pestis | | 分子名称: | D-alanine--D-alanine ligase, SODIUM ION | | 著者 | Tran, H.-T, Kang, L.-W, Hong, M.-K, Ngo, H.P.T, Huynh, K.H, Ahn, Y.J. | | 登録日 | 2015-05-10 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of D-alanine-D-alanine ligase from Yersinia pestis: nucleotide phosphate recognition by the serine loop.
Acta Crystallogr D Struct Biol, 72, 2016
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4BTQ
 | | Coordinates of the bacteriophage phi6 capsid subunits fitted into the cryoEM map EMD-1206 | | 分子名称: | MAJOR INNER PROTEIN P1 | | 著者 | Nemecek, D, Boura, E, Wu, W, Cheng, N, Plevka, P, Qiao, J, Mindich, L, Heymann, J.B, Hurley, J.H, Steven, A.C. | | 登録日 | 2013-06-18 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Subunit Folds and Maturation Pathway of a Dsrna Virus Capsid.
Structure, 21, 2013
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4BZH
 | | Crystal structure of galactose mutarotase GalM from Bacillus subtilis in complex with maltose and trehalose | | 分子名称: | ALDOSE 1-EPIMERASE, CITRIC ACID, GLYCEROL, ... | | 著者 | Vanden Broeck, A, Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | | 登録日 | 2013-07-25 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Galactose Mutarotase Galm from Bacillus Subtilis in Complex with Maltose and Trehalose
To be Published
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1VPC
 | | C-TERMINAL DOMAIN (52-96) OF THE HIV-1 REGULATORY PROTEIN VPR, NMR, 1 STRUCTURE | | 分子名称: | VPR PROTEIN | | 著者 | Schueler, W, De Rocquigny, H, Baudat, Y, Sire, J, Roques, B.P. | | 登録日 | 1998-02-20 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions.
J.Mol.Biol., 285, 1999
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1W7D
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3GAJ
 | | Structure of a C-terminal deletion variant of a PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COBALAMIN, Cobalamin adenosyltransferase PduO-like protein, ... | | 著者 | St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | | 登録日 | 2009-02-17 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme.
Biochemistry, 48, 2009
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1VP9
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4YHC
 | | Crystal structure of the WD40 domain of SCAP from fission yeast | | 分子名称: | CITRIC ACID, Sterol regulatory element-binding protein cleavage-activating protein | | 著者 | Gong, X, Li, J.X, Wu, J.P, Yan, C.Y, Yan, N. | | 登録日 | 2015-02-27 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.
Cell Res., 25, 2015
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5V8D
 | | Structure of Bacillus cereus PatB1 with sulfonyl adduct | | 分子名称: | Bacillus cereus PatB1, SULFATE ION | | 著者 | Sychantha, D, Little, D.J, Chapman, R.N, Boons, G.J, Robinson, H, Howell, P.L, Clarke, A.J. | | 登録日 | 2017-03-21 | | 公開日 | 2017-10-18 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.
Nat. Chem. Biol., 14, 2018
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8BHB
 | | GABA-A receptor a5 homomer - a5V3 - RO154513 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, ethyl 8-[(azanylidene-$l^{4}-azanylidene)amino]-5-methyl-6-oxidanylidene-4~{H}-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | | 著者 | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y, Wahid, A.A. | | 登録日 | 2022-10-30 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors.
Nat.Struct.Mol.Biol., 30, 2023
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3GBW
 | | Crystal structure of the first PHR domain of the Mouse Myc-binding protein 2 (MYCBP-2) | | 分子名称: | E3 ubiquitin-protein ligase MYCBP2 | | 著者 | Sampathkumar, P, Ozyurt, S.A, Wasserman, S.R, Klemke, R.L, Miller, S.A, Bain, K.T, Rutter, M.E, Tarun, G, Atwell, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-02-20 | | 公開日 | 2009-03-24 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1.
J.Mol.Biol., 397, 2010
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4CA0
 | | Structural Basis for the microtubule binding of the human kinetochore Ska complex | | 分子名称: | SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 | | 著者 | Abad, M, Medina, B, Santamaria, A, Zou, J, Plasberg-Hill, C, Madhumalar, A, Jayachandran, U, Redli, P.M, Rappsilber, J, Nigg, E.A, Jeyaprakash, A.A. | | 登録日 | 2013-10-04 | | 公開日 | 2014-01-22 | | 実験手法 | X-RAY DIFFRACTION (2.259 Å) | | 主引用文献 | Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
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1VP3
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4CB0
 | | Crystal structure of CpxAHDC in complex with ATP (hexagonal form) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION | | 著者 | Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. | | 登録日 | 2013-10-09 | | 公開日 | 2014-02-12 | | 最終更新日 | 2017-07-12 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
Plos Biol., 12, 2014
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4CC0
 | | Notch ligand, Jagged-1, contains an N-terminal C2 domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PROTEIN JAGGED-1, ... | | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | | 登録日 | 2013-10-17 | | 公開日 | 2013-11-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands
Cell Rep., 5, 2013
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5UNA
 | | Fragment of 7SK snRNA methylphosphate capping enzyme | | 分子名称: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, unidentified peptide section/fragment | | 著者 | Wu, H, Tempel, W, Dombrovski, L, McCarthy, A.A, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-01-30 | | 公開日 | 2017-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Fragment of 7SK snRNA methylphosphate capping enzyme
To Be Published
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3G9V
 | | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 | | 分子名称: | Interleukin 22 receptor, alpha 2, Interleukin-22 | | 著者 | de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I. | | 登録日 | 2009-02-14 | | 公開日 | 2009-04-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.756 Å) | | 主引用文献 | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
FEBS Lett., 583, 2009
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4C2X
 | | Human N-myristoyltransferase isoform 2 (NMT2) | | 分子名称: | 2-oxopentadecyl-CoA, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2, MAGNESIUM ION | | 著者 | Thinon, E, Serwa, R.A, Brannigan, J.A, Brassat, U, Wright, M.H, Heal, W.P, Wilkinson, A.J, Mann, D.J, Tate, E.W. | | 登録日 | 2013-08-20 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Global Profiling of Co- and Post-Translationally N-Myristoylated Proteomes in Human Cells.
Nat.Commun., 5, 2014
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