2IKC
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![BU of 2ikc by Molmil](/molmil-images/mine/2ikc) | Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Sheikh, I.A, Singh, N, Singh, A.K, Sharma, S, Singh, T.P. | 登録日 | 2006-10-02 | 公開日 | 2006-10-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate To be Published
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4DKR
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![BU of 4dkr by Molmil](/molmil-images/mine/4dkr) | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AWS-I-169 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ... | 著者 | Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D. | 登録日 | 2012-02-03 | 公開日 | 2012-05-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors. J.Med.Chem., 55, 2012
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2IOU
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![BU of 2iou by Molmil](/molmil-images/mine/2iou) | |
3NQ4
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![BU of 3nq4 by Molmil](/molmil-images/mine/3nq4) | |
3NZM
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3O4M
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![BU of 3o4m by Molmil](/molmil-images/mine/3o4m) | Crystal structure of porcine pancreatic phospholipase A2 in complex with 1,2-dihydroxybenzene | 分子名称: | CALCIUM ION, CATECHOL, Phospholipase A2, ... | 著者 | Dileep, K.V, Tintu, I, Karthe, P, Mandal, P.K, Haridas, M, Sadasivan, C. | 登録日 | 2010-07-27 | 公開日 | 2010-08-25 | 最終更新日 | 2011-11-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Binding to PLA(2) may contribute to the anti-inflammatory activity of catechol Chem.Biol.Drug Des., 2011
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3NZL
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![BU of 3nzl by Molmil](/molmil-images/mine/3nzl) | Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B | 分子名称: | DNA-binding protein SATB1 | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Kuzin, A.P, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-07-16 | 公開日 | 2010-09-22 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.199 Å) | 主引用文献 | Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B (CASP Target) To be Published
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3O9L
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![BU of 3o9l by Molmil](/molmil-images/mine/3o9l) | Design and optimisation of new piperidines as renin inhibitors | 分子名称: | (3R,4S)-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | 著者 | Corminboeuf, O, Bezencon, O, Grisostomi, C, Remen, L, Richard-Bildstein, S, Bur, D, Prade, L, Hess, P, Strickner, P, Treiber, A. | 登録日 | 2010-08-04 | 公開日 | 2011-03-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and optimization of new piperidines as renin inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3NP6
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![BU of 3np6 by Molmil](/molmil-images/mine/3np6) | The crystal structure of Berberine bound to DNA d(CGTACG) | 分子名称: | 5'-D(*CP*GP*TP*AP*CP*G)-3', BERBERINE, CALCIUM ION | 著者 | Ferraroni, M, Bazzicalupi, C, Gratteri, P, Bilia, A.R. | 登録日 | 2010-06-28 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG) Chem.Commun.(Camb.), 47, 2011
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8H94
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![BU of 8h94 by Molmil](/molmil-images/mine/8h94) | Structure of mouse SCMC bound with KH domain of FILIA | 分子名称: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | 著者 | Chi, P, Ou, G, Han, Z, Li, J, Deng, D. | 登録日 | 2022-10-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H96
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![BU of 8h96 by Molmil](/molmil-images/mine/8h96) | Structure of mouse SCMC core complex | 分子名称: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | 著者 | Chi, P, Ou, G, Li, J, Han, Z, Deng, D. | 登録日 | 2022-10-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H95
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![BU of 8h95 by Molmil](/molmil-images/mine/8h95) | Structure of mouse SCMC bound with full-length FILIA | 分子名称: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | 著者 | Chi, P, Ou, G, Han, Z, Li, L, Deng, D. | 登録日 | 2022-10-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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6CI6
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![BU of 6ci6 by Molmil](/molmil-images/mine/6ci6) | Crystal structure of equine serum albumin in complex with nabumetone | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Serum albumin, ... | 著者 | Venkataramany, B.S, Czub, M.P, Shabalin, I.G, Handing, K.B, Steen, E.H, Cooper, D.R, Joachimiak, A, Satchell, K.J.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-02-23 | 公開日 | 2018-03-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma. J.Med.Chem., 2020
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4UV2
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![BU of 4uv2 by Molmil](/molmil-images/mine/4uv2) | Structure of the curli transport lipoprotein CsgG in a non-lipidated, pre-pore conformation | 分子名称: | CURLI PRODUCTION TRANSPORT COMPONENT CSGG | 著者 | Goyal, P, Krasteva, P.V, Gerven, N.V, Gubellini, F, Broeck, I.V.D, Troupiotis-Tsailaki, A, Jonckheere, W, Pehau-Arnaudet, G, Pinkner, J.S, Chapman, M.R, Hultgren, S.J, Howorka, S, Fronzes, R, Remaut, H. | 登録日 | 2014-08-04 | 公開日 | 2014-09-24 | 最終更新日 | 2014-12-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg. Nature, 516, 2014
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6CSD
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![BU of 6csd by Molmil](/molmil-images/mine/6csd) | V308E mutant of cytochrome P450 2D6 complexed with prinomastat | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Yang, Y.T, Fujita, K, Wang, P.F, Im, S.C, Pearl, N.M, Meagher, J, Stuckey, J, Waskell, L. | 登録日 | 2018-03-20 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.391 Å) | 主引用文献 | Characteristic conformational changes on the distal and proximal surfaces of cytochrome P450 2D6 in response to substrate binding To Be Published
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8H8F
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![BU of 8h8f by Molmil](/molmil-images/mine/8h8f) | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state) | 分子名称: | Proton-activated chloride channel | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | 登録日 | 2022-10-22 | 公開日 | 2024-05-01 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA. Cell Res., 2024
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8H8D
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![BU of 8h8d by Molmil](/molmil-images/mine/8h8d) | Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (intermediate state) | 分子名称: | Proton-activated chloride channel | 著者 | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | 登録日 | 2022-10-22 | 公開日 | 2024-05-01 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | 主引用文献 | Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA. Cell Res., 2024
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6CVE
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![BU of 6cve by Molmil](/molmil-images/mine/6cve) | Crystal structure of Mycobacterium tuberculosis dethiobiotin Synthetase in complex with cytidine triphosphate and 7,8-diaminopelargonic acid | 分子名称: | 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ATP-dependent dethiobiotin synthetase BioD, CITRATE ANION, ... | 著者 | Thompson, A.P, Bruning, J.B, Wegener, K.L, Polyak, S.W. | 登録日 | 2018-03-28 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes Acs Catalysis, 8(11), 2018
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6CZB
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![BU of 6czb by Molmil](/molmil-images/mine/6czb) | Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with uridine triphosphate (UTP) - promiscuous binding mode with disordered nucleoside | 分子名称: | ATP-dependent dethiobiotin synthetase BioD, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE | 著者 | Thompson, A.P, Wegener, K.L, Bruning, J.B, Polyak, S.W. | 登録日 | 2018-04-09 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes Acs Catalysis, 8(11), 2018
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6CYQ
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![BU of 6cyq by Molmil](/molmil-images/mine/6cyq) | Crystal structure of CTX-M-14 S70G/N106S beta-lactamase in complex with hydrolyzed cefotaxime | 分子名称: | (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-methylidene-5,6-dihydro -2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, GLYCEROL | 著者 | Patel, M.P, Hu, L, Sankaran, B, Brown, C, Prasad, B.V.V, Palzkill, T. | 登録日 | 2018-04-06 | 公開日 | 2018-10-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance. J. Biol. Chem., 293, 2018
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9JA1
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9BOQ
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![BU of 9boq by Molmil](/molmil-images/mine/9boq) | Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer) | 分子名称: | 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Nandi, P, DeVore, K, Chiu, P.-L. | 登録日 | 2024-05-05 | 公開日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors. Commun Chem, 7, 2024
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6CQF
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![BU of 6cqf by Molmil](/molmil-images/mine/6cqf) | Crystal structure of HPK1 in complex an inhibitor G1858 | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 1, N-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3R)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-pyrazolo[4,3-c]pyridin-6-amine | 著者 | Wu, P, Lehoux, I, Mortara, K, Franke, Y, Chan, B.K, Wang, W. | 登録日 | 2018-03-15 | 公開日 | 2018-12-19 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.246 Å) | 主引用文献 | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure, 27, 2019
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6CVV
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![BU of 6cvv by Molmil](/molmil-images/mine/6cvv) | Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with adenosine triphosphate (ATP) - promiscuous binding mode with disordered nucleoside | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent dethiobiotin synthetase BioD, MAGNESIUM ION | 著者 | Thompson, A.P, Wegener, K.L, Bruning, J.B, Polyak, S.W. | 登録日 | 2018-03-29 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes Acs Catalysis, 8(11), 2018
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6CZC
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![BU of 6czc by Molmil](/molmil-images/mine/6czc) | Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with thymidine triphosphate (TTP) - promiscuous binding mode with disordered nucleoside | 分子名称: | ATP-dependent dethiobiotin synthetase BioD, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE | 著者 | Thompson, A.P, Wegener, K.L, Bruning, J.B, Polyak, S.W. | 登録日 | 2018-04-09 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes Acs Catalysis, 8(11), 2018
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