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PDB: 45712 件

7MP2
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CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 1,5-BISDIPHOSPHATE TETRAKISPHOSPHATE (1,5-PP IP4)
分子名称: (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], S-arrestin
著者Sander, C.L, Palczewski, K, Kiser, P.D.
登録日2021-05-04
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
7CSD
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AtPrR1 with NADP+ and (+)lariciresinol
分子名称: 4-[[(3R,4R,5S)-4-(hydroxymethyl)-5-(3-methoxy-4-oxidanyl-phenyl)oxolan-3-yl]methyl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1
著者Shao, K, Zhang, P.
登録日2020-08-14
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79709971 Å)
主引用文献Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
1JQ9
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Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Phe-Leu-Ser-Tyr-Lys at 1.8 resolution
分子名称: ACETIC ACID, Peptide inhibitor, Phospholipase A2
著者Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P.
登録日2001-08-04
公開日2002-11-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
7MP0
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CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 5-DIPHOSPHATE PENTAKISPHOSPHATE (5-PP IP5)
分子名称: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, 2-ETHOXYETHANOL, S-arrestin
著者Sander, C.L, Palczewski, K, Kiser, P.D.
登録日2021-05-04
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
5UJG
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ovGRN12-35_3s
分子名称: Granulin
著者Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N.
登録日2017-01-17
公開日2018-01-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.
J. Med. Chem., 60, 2017
7CSF
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AtPrR1 with NADP+ and (-)secoisolariciresinol
分子名称: (2R,3R)-2,3-bis[(3-methoxy-4-oxidanyl-phenyl)methyl]butane-1,4-diol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1
著者Shao, K, Zhang, P.
登録日2020-08-14
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98241806 Å)
主引用文献Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
2P2I
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Crystal structure of the VEGFR2 kinase domain in complex with a nicotinamide inhibitor
分子名称: N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide, Vascular endothelial growth factor receptor 2
著者Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H.
登録日2007-03-07
公開日2007-03-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor
J.Med.Chem., 50, 2007
7MP1
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CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1,5-DI-METHYLENEBISPHOSPHONATE INOSITOL TETRAKISPHOSPHATE (1,5-PCP-IP4)
分子名称: S-arrestin, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid)
著者Sander, C.L, Palczewski, K, Kiser, P.D.
登録日2021-05-04
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
3IHJ
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Human alanine aminotransferase 2 in complex with PLP
分子名称: Alanine aminotransferase 2, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日2009-07-30
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Human glutamate pyruvate transaminase 2
To be Published
7CSB
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AtPrR1 with NADP+ and (+)pinoresinol
分子名称: 4-[(3S,3aR,6S,6aR)-6-(3-methoxy-4-oxidanyl-phenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1
著者Shao, K, Zhang, P.
登録日2020-08-14
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.002017 Å)
主引用文献Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases.
Nat Commun, 12, 2021
5URN
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NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the transactivation domain 1 of p65
分子名称: RNA polymerase II transcription factor B subunit 1, Transcription factor p65
著者Lecoq, L, Omichinski, J.G, Raiola, L, Cyr, N, Chabot, P, Arseneault, G, Legault, P.
登録日2017-02-11
公開日2017-03-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-kappa B and transcription regulatory factors.
Nucleic Acids Res., 45, 2017
4X9N
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Dithionite reduced L-alpha-Glycerophosphate Oxidase from Mycoplasma pneumoniae with FAD bound
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-alpha-glycerophosphate oxidase, NICKEL (II) ION
著者Elkhal, C.K, Kean, K.M, Parsonage, D, Claiborne, A, Karplus, P.A.
登録日2014-12-11
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structure and proposed mechanism of l-alpha-glycerophosphate oxidase from Mycoplasma pneumoniae.
Febs J., 282, 2015
7LBF
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CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ...
著者Kschonsak, M, Rouge, L, Arthur, C.P, Hoangdung, H, Patel, N, Kim, I, Johnson, M, Kraft, E, Rohou, A.L, Gill, A, Martinez-Martin, N, Payandeh, J, Ciferri, C.
登録日2021-01-07
公開日2021-03-10
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.
Cell, 184, 2021
7BTU
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Crystal structure of TrmO from P. areuginosa
分子名称: Putative tRNA (Adenine(37)-N6)-methyltransferase
著者Fan, C.P.
登録日2020-04-03
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of TrmO
To Be Published
1SXN
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REDUCED BOVINE SUPEROXIDE DISMUTASE AT PH 5.0
分子名称: CALCIUM ION, COPPER (II) ION, CU, ...
著者Ferraroni, M, Rypniewski, W.R, Bruni, B, Orioli, P, Wilson, K.S, Mangani, S.
登録日1997-09-17
公開日1998-03-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site.
J.Biol.Inorg.Chem., 3, 1998
410D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE
分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(T38)P*AP*CP*GP*C)-3'), SPERMINE
著者Tereshko, V, Portmann, S, Tay, E.C, Martin, P, Natt, F, Altmann, K.H, Egli, M.
登録日1998-06-30
公開日1998-07-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
412D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHYL-[TRI(OXYETHYL)] RIBONUCLEOSIDE
分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3'), MAGNESIUM ION
著者Tereshko, V, Portmann, S, Tay, E.C, Martin, P, Natt, F, Altmann, K.H, Egli, M.
登録日1998-06-30
公開日1998-07-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
5G2X
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Structure a of Group II Intron Complexed with its Reverse Transcriptase
分子名称: 5'-R(*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*CP)-3', GROUP II INTRON, GROUP II INTRON-ENCODED PROTEIN LTRA
著者Qu, G, Kaushal, P.S, Wang, J, Shigematsu, H, Piazza, C.L, Agrawal, R.K, Belfort, M, Wang, H.W.
登録日2016-04-16
公開日2016-05-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of a Group II Intron in Complex with its Reverse Transcriptase.
Nat.Struct.Mol.Biol., 23, 2016
7LWJ
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Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-01
公開日2021-03-31
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
4Y30
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Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and EPZ020411
分子名称: GLYCEROL, MAGNESIUM ION, N,N'-dimethyl-N-({3-[4-({trans-3-[2-(tetrahydro-2H-pyran-4-yl)ethoxy]cyclobutyl}oxy)phenyl]-1H-pyrazol-4-yl}methyl)ethane-1,2-diamine, ...
著者Swinger, K.K, Boriack-Sjodin, P.A.
登録日2015-02-10
公開日2015-04-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
Acs Med.Chem.Lett., 6, 2015
6C0W
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Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A
分子名称: 147 mer DNA, Centromere protein N, Histone H2A, ...
著者Zhou, K, Pentakota, S, Vetter, I.R, Morgan, G.P, Petrovic, A, Musacchio, A, Luger, K.
登録日2018-01-02
公開日2018-01-17
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Decoding the centromeric nucleosome through CENP-N.
Elife, 6, 2017
7LWI
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Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-01
公開日2021-03-31
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LWM
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Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-01
公開日2021-03-31
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
2W2M
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WT PCSK9-DELTAC BOUND TO WT EGF-A OF LDLR
分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
著者Bottomley, M.J, Cirillo, A, Orsatti, L, Ruggeri, L, Fisher, T.S, Santoro, J.C, Cummings, R.T, Cubbon, R.M, Lo Surdo, P, Calzetta, A, Noto, A, Baysarowich, J, Mattu, M, Talamo, F, De Francesco, R, Sparrow, C.P, Sitlani, A, Carfi, A.
登録日2008-11-03
公開日2008-11-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
J.Biol.Chem., 284, 2009
7LWW
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Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 1-RBD-up conformation (S-GSAS-D614G-K417N-E484K-N501Y)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-01
公開日2021-03-31
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021

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件を2024-07-17に公開中

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