1JNW
| Active Site Structure of E. coli pyridoxine 5'-phosphate Oxidase | 分子名称: | FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | di Salvo, M.L, Ko, T.P, Musayev, F.N, Raboni, S, Schirch, V, Safo, M.K. | 登録日 | 2001-07-25 | 公開日 | 2001-08-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase. J.Mol.Biol., 315, 2002
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6H8V
| Beta-phosphoglucomutase from Lactococcus lactis in an open conformer in the P21 spacegroup to 1.8 A. | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, Beta-phosphoglucomutase, ... | 著者 | Robertson, A.J, Bisson, C, Waltho, J.P. | 登録日 | 2018-08-03 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Transition state of phospho-enzyme hydrolysis in beta-phosphoglucomutase. To Be Published
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6BLF
| PDE2 complexed with 2-[6-fluoro-8-methylsulfonyl-9-[(1R)-1-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid | 分子名称: | MAGNESIUM ION, ZINC ION, [(1S)-6-fluoro-8-(methylsulfonyl)-9-{(1R)-1-[4-(trifluoromethyl)phenyl]ethyl}-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetic acid, ... | 著者 | Su, H.P. | 登録日 | 2017-11-10 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Hydrolase complex To Be Published
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3ZIZ
| Crystal structure of Podospora anserina GH5 beta-(1,4)-mannanase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GH5 ENDO-BETA-1,4-MANNANASE, GLYCEROL | 著者 | Couturier, M, Roussel, A, Rosengren, A, Leone, P, Stalbrand, H, Berrin, J.G. | 登録日 | 2013-01-15 | 公開日 | 2013-04-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and Biochemical Analyses of Glycoside Hydrolase Families 5 and 26 Beta-(1,4)-Mannanases from Podospora Anserina Reveal Differences Upon Manno-Oligosaccharides Catalysis. J.Biol.Chem., 288, 2013
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3D7R
| Crystal structure of a putative esterase from Staphylococcus aureus | 分子名称: | BROMIDE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Lam, R, Battaile, K.P, Chan, T, Romanov, V, Lam, K, Soloveychik, M, Wu-Brown, J, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2008-05-21 | 公開日 | 2009-06-09 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of a putative esterase from Staphylococcus aureus To be Published
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2W0H
| X ray structure of Leishmania infantum Trypanothione reductase in complex with antimony and NADPH | 分子名称: | ANTIMONY (III) ION, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Baiocco, P, Colotti, G, Franceschini, S, Ilari, A. | 登録日 | 2008-08-18 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular Basis of Antimony Treatment in Leishmaniasis. J.Med.Chem., 52, 2009
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5U7O
| Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-626529 in Complex with Human Antibodies PGT122 and 35O22 at 3.8 Angstrom | 分子名称: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pancera, M, Lai, Y.-T, Kwong, P.D. | 登録日 | 2016-12-12 | 公開日 | 2017-08-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.031 Å) | 主引用文献 | Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529. Nat. Chem. Biol., 13, 2017
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2W7L
| Crystal structure of Y61AbsSHMT L-allo-Threonine external aldimine | 分子名称: | ALLO-THREONINE, PYRIDOXAL-5'-PHOSPHATE, SERINE HYDROXYMETHYLTRANSFERASE | 著者 | Rajaram, V, Bhavani, B.S, Bisht, S, Kaul, P, Prakash, V, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2008-12-22 | 公開日 | 2010-08-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Importance of Tyrosine Residues of Bacillus Stearothermophilus Serine Hydroxymethyltransferase in Cofactor Binding and L-Allo-Thr Cleavage. FEBS J., 275, 2008
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6FLW
| Structure of AcmJRL, a mannose binding jacalin related lectin from Ananas comosus. | 分子名称: | CITRIC ACID, Jacalin-like lectin | 著者 | Azarkan, M, Herman, R, El Mahyaoui, R, Sauvage, E, Vanden Broeck, A, Charlier, P. | 登録日 | 2018-01-29 | 公開日 | 2018-08-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biochemical and structural characterization of a mannose binding jacalin-related lectin with two-sugar binding sites from pineapple (Ananas comosus) stem. Sci Rep, 8, 2018
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5EHM
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6BJ6
| Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-{[(S)-benzenesulfinyl]methyl}benzoic acid | 分子名称: | 2-{[(S)-phenylsulfinyl]methyl}benzoic acid, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | 登録日 | 2017-11-05 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 2-{[(S)-benzenesulfinyl]methyl}benzoic acid To Be Published
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3NR8
| Crystal structure of human SHIP2 | 分子名称: | CHLORIDE ION, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2010-06-30 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases Structure, 22, 2014
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1RSD
| DHNA complex with 3-(5-Amino-7-hydroxy-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl)-N-[2-(2-hydroxymethyl-phenylsulfanyl)-benzyl]-benzamide | 分子名称: | 3-(5-AMINO-7-HYDROXY-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-2-YL)-N-[2-(2-(HYDROXYMETHYL-PHENYLSULFANYL)-BENZYL]-BENZAMIDE, Dihydroneopterin aldolase | 著者 | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | 登録日 | 2003-12-09 | 公開日 | 2004-03-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization. J.Med.Chem., 47, 2004
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2W7K
| Crystal structure of Y61AbsSHMT L-Serine external aldimine | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE, SERINE HYDROXYMETHYLTRANSFERASE | 著者 | Rajaram, V, Bhavani, B.S, Bisht, S, Kaul, P, Prakash, V, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2008-12-22 | 公開日 | 2010-08-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Importance of Tyrosine Residues of Bacillus Stearothermophilus Serine Hydroxymethyltransferase in Cofactor Binding and L-Allo-Thr Cleavage. FEBS J., 275, 2008
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2FX9
| Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41 | 分子名称: | Fab 4E10, Fragment of HIV glycoprotein gp41 | 著者 | Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A. | 登録日 | 2006-02-03 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J.Mol.Biol., 365, 2007
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1FHT
| RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES | 分子名称: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | 著者 | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | 登録日 | 1996-02-21 | 公開日 | 1996-07-11 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding. J.Mol.Biol., 257, 1996
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6FPA
| Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group P212121 | 分子名称: | DARPin 1238_G01 | 著者 | Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. | 登録日 | 2018-02-09 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations. Biol Open, 7, 2018
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3ZV3
| CRYSTAL STRUCTURE OF CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE (BPHB)FROM PANDORAEA PNOMENUSA STRAIN B-356 IN INTERMEDIATE STATE OF SUBSTRATE BINDING LOOP | 分子名称: | CIS-2,3-DIHYDROBIPHENYL-2,3-DIOL DEHYDROGENASE | 著者 | Dhindwal, S, Patil, D.N, Kumar, P. | 登録日 | 2011-07-23 | 公開日 | 2011-08-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Biochemical Studies and Ligand-Bound Structures of Biphenyl Dehydrogenase from Pandoraea Pnomenusa Strain B-356 Reveal a Basis for Broad Specificity of the Enzyme. J.Biol.Chem., 286, 2011
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2W2K
| Crystal structure of the apo forms of Rhodotorula graminis D- mandelate dehydrogenase at 1.8A. | 分子名称: | D-MANDELATE DEHYDROGENASE | 著者 | Vachieri, S.G, Cole, A.R, Bagneris, C, Baker, D.P, Fewson, C.A, Basak, A.K. | 登録日 | 2008-11-02 | 公開日 | 2009-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase To be Published
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8AMY
| High-resolution crystal structure of the Mu8.1 conotoxin from Conus Mucronatus | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BICARBONATE ION, ... | 著者 | Mueller, E, Hackney, C.M, Ellgaard, L, Morth, J.P. | 登録日 | 2022-08-04 | 公開日 | 2023-08-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | High-resolution crystal structure of the Mu8.1 conotoxin from Conus mucronatus. Acta Crystallogr.,Sect.F, 79, 2023
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5YF5
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3ZWA
| CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1 (RPMFE1) COMPLEXED WITH 3S-HYDROXY-HEXANOYL-COA | 分子名称: | (S)-3-Hydroxyhexanoyl-CoA, GLYCEROL, PEROXISOMAL BIFUNCTIONAL ENZYME, ... | 著者 | Kasaragod, P, Schmitz, W, Hiltunen, J.K, Wierenga, R.K. | 登録日 | 2011-07-28 | 公開日 | 2012-08-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | The Isomerase and Hydratase Reaction Mechanism of the Crotonase Active Site of the Multifunctional Enzyme (Type-1), as Deduced from Structures of Complexes with 3S-Hydroxy- Acyl-Coa. FEBS J., 280, 2013
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6FR7
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6HI4
| The ATAD2 bromodomain in complex with compound 7 | 分子名称: | (2~{R})-2-azanyl-~{N}-[4-ethanoyl-5-(3-methoxyphenyl)-1,3-thiazol-2-yl]propanamide, ATPase family AAA domain-containing protein 2, SULFATE ION | 著者 | Sledz, P, Caflisch, A. | 登録日 | 2018-08-29 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers. Acs Med.Chem.Lett., 11, 2020
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6HJJ
| Crystal structure of Aurora-A L210C catalytic domain in complex with ASDO6 ligand | 分子名称: | 2,5,8,11-TETRAOXATRIDECANE, ACETATE ION, Aurora kinase A, ... | 著者 | Bayliss, R, McIntyre, P.J. | 登録日 | 2018-09-04 | 公開日 | 2018-10-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases. ACS Chem. Biol., 13, 2018
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