1E6I
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2R51
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![BU of 2r51 by Molmil](/molmil-images/mine/2r51) | Crystal Structure of mouse Vps26B | Descriptor: | Vacuolar protein sorting-associated protein 26B | Authors: | Owen, D.J, Teasdale, R.D, Collins, B.M. | Deposit date: | 2007-09-02 | Release date: | 2008-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Vps26B and mapping of its interaction with the retromer protein complex. Traffic, 9, 2008
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6RH6
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![BU of 6rh6 by Molmil](/molmil-images/mine/6rh6) | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163 | Descriptor: | AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1 | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | Deposit date: | 2019-04-18 | Release date: | 2019-09-04 | Method: | SOLUTION NMR | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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1HES
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1PHK
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![BU of 1phk by Molmil](/molmil-images/mine/1phk) | TWO STRUCTURES OF THE CATALYTIC DOMAIN OF PHOSPHORYLASE, KINASE: AN ACTIVE PROTEIN KINASE COMPLEXED WITH NUCLEOTIDE, SUBSTRATE-ANALOGUE AND PRODUCT | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PHOSPHORYLASE KINASE | Authors: | Owen, D.J, Noble, M.E.M, Garman, E.F, Papageorgiou, A.C, Johnson, L.N. | Deposit date: | 1996-03-15 | Release date: | 1996-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product. Structure, 3, 1995
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1URF
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![BU of 1urf by Molmil](/molmil-images/mine/1urf) | HR1b domain from PRK1 | Descriptor: | PROTEIN KINASE C-LIKE 1 | Authors: | Owen, D, Lowe, P.N, Nietlispach, D, Brosnan, C.E, Chirgadze, D.Y, Parker, P.J, Blundell, T.L, Mott, H.R. | Deposit date: | 2003-10-29 | Release date: | 2003-11-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Molecular Dissection of the Interaction between the Small G Proteins Rac1 and Rhoa and Protein Kinase C-Related Kinase 1 (Prk1) J.Biol.Chem., 278, 2003
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6RH5
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![BU of 6rh5 by Molmil](/molmil-images/mine/6rh5) | Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain | Descriptor: | Adaptin ear-binding coat-associated protein 1 | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | Deposit date: | 2019-04-18 | Release date: | 2019-09-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation. Dev.Cell, 50, 2019
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6TL0
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![BU of 6tl0 by Molmil](/molmil-images/mine/6tl0) | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of VPS29 with VARP 687-747 | Descriptor: | Ankyrin repeat domain-containing protein 27, Vacuolar protein sorting-associated protein 29, ZINC ION | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Crawley-Snowdon, H. | Deposit date: | 2019-11-29 | Release date: | 2020-10-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29. Nat Commun, 11, 2020
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5FPI
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1BB9
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![BU of 1bb9 by Molmil](/molmil-images/mine/1bb9) | |
1BXX
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1BW8
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2VGL
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![BU of 2vgl by Molmil](/molmil-images/mine/2vgl) | AP2 CLATHRIN ADAPTOR CORE | Descriptor: | ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ... | Authors: | Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R. | Deposit date: | 2007-11-14 | Release date: | 2007-12-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Architecture and Functional Model of the Endocytic Ap2 Complex Cell(Cambridge,Mass.), 109, 2002
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1B9K
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1E42
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![BU of 1e42 by Molmil](/molmil-images/mine/1e42) | Beta2-adaptin appendage domain, from clathrin adaptor AP2 | Descriptor: | AP-2 COMPLEX SUBUNIT BETA, CHLORIDE ION, DITHIANE DIOL, ... | Authors: | Owen, D.J, Evans, P.R, McMahon, H.T. | Deposit date: | 2000-06-27 | Release date: | 2000-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure and Function of the Beta2-Adaptin Appendage Domain Embo J., 19, 2000
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2V8S
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![BU of 2v8s by Molmil](/molmil-images/mine/2v8s) | VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX | Descriptor: | CLATHRIN INTERACTOR 1, GLYCEROL, VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B | Authors: | Owen, D.J, McCoy, A.J, Collins, B.M, Miller, S.E. | Deposit date: | 2007-08-14 | Release date: | 2007-11-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | A Snare-Adaptor Interaction is a New Mode of Cargo Recognition in Clathrin Coated Vesicles Nature, 450, 2007
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5C7Z
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2JKT
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![BU of 2jkt by Molmil](/molmil-images/mine/2jkt) | AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ... | Authors: | Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R. | Deposit date: | 2008-08-29 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex. Nature, 456, 2008
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2JKR
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![BU of 2jkr by Molmil](/molmil-images/mine/2jkr) | AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ... | Authors: | Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R. | Deposit date: | 2008-08-29 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex. Nature, 456, 2008
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2G30
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![BU of 2g30 by Molmil](/molmil-images/mine/2g30) | beta appendage of AP2 complexed with ARH peptide | Descriptor: | 16-mer peptide from Low density lipoprotein receptor adapter protein 1, AP-2 complex subunit beta-1, peptide sequence AAF | Authors: | Edeling, M.A, Collins, B.M, Traub, L.M, Owen, D.J. | Deposit date: | 2006-02-17 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular Switches Involving the AP-2 beta2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly Dev.Cell, 10, 2006
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4UQI
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![BU of 4uqi by Molmil](/molmil-images/mine/4uqi) | AP2 controls clathrin polymerization with a membrane-activated switch | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... | Authors: | Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. | Deposit date: | 2014-06-23 | Release date: | 2014-07-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch. Science, 345, 2014
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7SLZ
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![BU of 7slz by Molmil](/molmil-images/mine/7slz) | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596 | Descriptor: | Glucose-induced degradation protein 4 homolog, N-[(1s,4s)-4-(1H-benzimidazol-2-yl)cyclohexyl]-N~2~-[(1H-indol-2-yl)methyl]glycinamide | Authors: | Song, X, Dong, A, Calabrese, M, Wang, F, Owen, D, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-10-25 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596 To Be Published
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2RMK
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![BU of 2rmk by Molmil](/molmil-images/mine/2rmk) | Rac1/PRK1 Complex | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1, ... | Authors: | Modha, R, Campbell, L.J, Nietlispach, D, Buhecha, H.R, Owen, D, Mott, H.R. | Deposit date: | 2007-10-25 | Release date: | 2007-11-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1 J.Biol.Chem., 283, 2008
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8V1P
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![BU of 8v1p by Molmil](/molmil-images/mine/8v1p) | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH UBF9092 | Descriptor: | Glucose-induced degradation protein 4 homolog, N,N~2~-bis[(4-methoxyphenyl)methyl]glycinamide | Authors: | Dong, C, Dong, A, Calabrese, M, Wang, F, Owen, D, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2023-11-21 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH UBF9092 To be published
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2BP5
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![BU of 2bp5 by Molmil](/molmil-images/mine/2bp5) | MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG | Descriptor: | CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4 | Authors: | Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D. | Deposit date: | 2005-04-18 | Release date: | 2005-07-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors. J.Cell.Sci, 118, 2005
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