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PDB: 7 件
6U2O
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BU of 6u2o by Molmil
Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
著者Ouzon-Shubeita, H, Vilas, C.K, Lee, S.
登録日2019-08-20
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the Mutagenic Bypass of the Major Cisplatin-DNA Lesion by Human DNA Polymerase Beta Reveal Insights into Cisplatin-Induced Mutagenesis
To Be Published
6U6B
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BU of 6u6b by Molmil
Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
著者Ouzon-Shubeita, H, Vilas, C.K, Lee, S.
登録日2019-08-29
公開日2020-09-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.108 Å)
主引用文献Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion.
Biochem.J., 477, 2020
6MXO
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BU of 6mxo by Molmil
Structure of HPoleta incorporating dCTP opposite the 3-prime Pt(DACH)-GG
分子名称: (cyclohex-1-ene-1,2-diamine)platinum(2+), 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ...
著者Ouzon-Shubeita, H, Lee, S.
登録日2018-10-31
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase eta.
Biochem. J., 476, 2019
5CHZ
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BU of 5chz by Molmil
Structure of wild-type human MBD4 bound to a G:T mismatch
分子名称: 12-mer DNA(G), 5-mer DNA, 7-mer DNA, ...
著者Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
登録日2015-07-10
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure of wild-type human MBD4 bound to a G:T mismatch
To Be Published
4OFA
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BU of 4ofa by Molmil
Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
分子名称: 12-mer DNA(G), 12-mer DNA(T), MAGNESIUM ION, ...
著者Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
登録日2014-01-14
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of MBD4 bound to G:T mispair DNA
To be Published
4OFH
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BU of 4ofh by Molmil
Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
分子名称: 12-mer DNA(O6MeG), 12-mer DNA(T), MAGNESIUM ION, ...
著者Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
登録日2014-01-14
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure of MBD4 bound to O6MeG:T mispair DNA
To be Published
4OFE
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BU of 4ofe by Molmil
Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
分子名称: 12-mer DNA(G), 12-mer DNA(T), MAGNESIUM ION, ...
著者Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
登録日2014-01-14
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of R468K/D560N MBD4 bound to G:T mispair DNA
To be Published

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件を2024-10-09に公開中

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