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PDB: 3 件

8KFQ
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BU of 8kfq by Molmil
The crystal structure of EGFR(T797M/L858R) with small molecule inhibitor B6
分子名称: Epidermal growth factor receptor, SULFATE ION, ~{N}-[3-[[6-chloranyl-2-[(1-ethylpyrazol-4-yl)amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide
著者Wu, C, Ouyang, L.
登録日2023-08-16
公開日2024-08-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structure of EGFR(T979M/L858R) with small molecule inhibitor B6
To Be Published
7XBI
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BU of 7xbi by Molmil
The crystal structure of human TrkA kinase bound to the inhibitor
分子名称: 4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{N}-[3-(1-methylpyrazol-4-yl)-1~{H}-indazol-5-yl]-2-(trifluoromethyl)benzamide, CHLORIDE ION, High affinity nerve growth factor receptor
著者Wu, C.Y, Wang, G, Ouyang, L.
登録日2022-03-21
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The crystal structure of human TrkA kinase bound to the inhibitor
To be published
5HA9
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BU of 5ha9 by Molmil
Crystal structure-based design and disovery of a novel PARP1 antiagonist (BL-PA10) that induces apoptosis and inhibits metastasis in triple negative breast cancer
分子名称: Amitriptyline, GLYCEROL, Poly [ADP-ribose] polymerase 1, ...
著者Fu, L, Peng, H, Zhang, L, Ouyang, L.
登録日2015-12-30
公開日2016-03-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献Crystal structure-based discovery of a novel synthesized PARP1 inhibitor (OL-1) with apoptosis-inducing mechanisms in triple-negative breast cancer.
Sci Rep, 6, 2016

226707

件を2024-10-30に公開中

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