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PDB: 87 件

8DF8
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Structure of M. kandleri topoisomerase V in complex with DNA. 40 base pair symmetric DNA complex
分子名称: DNA (42-MER), PHOSPHATE ION, PHOSPHITE ION, ...
著者Osterman, A, Mondragon, A.
登録日2022-06-21
公開日2022-08-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Elife, 11, 2022
8DFB
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Structure of M. kandleri topoisomerase V in complex with DNA. 39 base pair symmetric DNA complex
分子名称: DNA (40-MER), POTASSIUM ION, Topoisomerase V
著者Osterman, A, Mondragon, A.
登録日2022-06-21
公開日2022-08-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Elife, 11, 2022
8DF7
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Structure of M. kandleri topoisomerase V in complex with DNA. 38 base pair symmetric DNA complex
分子名称: DNA (39-MER), POTASSIUM ION, Topoisomerase V
著者Osterman, A, Mondragon, A.
登録日2022-06-21
公開日2022-08-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Elife, 11, 2022
8DF9
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Structure of M. kandleri topoisomerase V in complex with DNA. 38 base pair asymmetric DNA complex
分子名称: DNA (33-MER), DNA (5'-D(P*GP*CP*CP*TP*GP*CP*AP*CP*GP*AP*AP*GP*TP*AP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*TP*GP*CP*AP*CP*GP*AP*AP*GP*TP*AP*AP*GP*CP*A)-3'), ...
著者Osterman, A, Mondragon, A.
登録日2022-06-21
公開日2022-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Elife, 11, 2022
1L2K
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Neutron Structure Determination of Sperm Whale Met-Myoglobin at 1.5A Resolution.
分子名称: AMMONIUM CATION WITH D, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ostermann, A, Tanaka, I, Engler, N, Niimura, N, Parak, F.G.
登録日2002-02-21
公開日2002-08-21
最終更新日2024-04-03
実験手法NEUTRON DIFFRACTION (1.5 Å)
主引用文献Hydrogen and deuterium in myoglobin as seen by a neutron structure determination at 1.5 A resolution.
Biophys.Chem., 95, 2002
1DO4
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CARBONMONOXY-MYOGLOBIN (MUTANT L29W) AFTER PHOTOLYSIS AT T<180K
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U.
登録日1999-12-18
公開日2000-01-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
1DO7
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CARBONMONOXY-MYOGLOBIN (MUTANT L29W) REBINDING STRUCTURE AFTER PHOTOLYSIS AT T< 180K
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U.
登録日1999-12-19
公開日2000-01-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
1DO1
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CARBONMONOXY-MYOGLOBIN MUTANT L29W AT 105K
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U.
登録日1999-12-18
公開日2000-01-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
1DO3
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CARBONMONOXY-MYOGLOBIN (MUTANT L29W) AFTER PHOTOLYSIS AT T>180K
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Ostermann, A, Waschipky, R, Parak, F.G, Nienhaus, G.U.
登録日1999-12-18
公開日2000-01-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Ligand binding and conformational motions in myoglobin.
Nature, 404, 2000
1H72
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HOMOSERINE KINASE, L-HOMOSERINE, ...
著者Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H.
登録日2001-07-02
公開日2001-09-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1H73
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH THREONINE
分子名称: HOMOSERINE KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, THREONINE
著者Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H.
登録日2001-07-02
公開日2001-09-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase
Biochemistry, 40, 2001
1QU4
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CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE
分子名称: ORNITHINE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE
著者Grishin, N.V, Osterman, A.L, Brooks, H.B, Phillips, M.A, Goldsmith, E.J.
登録日1999-07-06
公開日1999-11-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine.
Biochemistry, 38, 1999
1YB0
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Structure of PlyL
分子名称: PHOSPHATE ION, ZINC ION, prophage LambdaBa02, ...
著者Low, L.Y, Yang, C, Perego, M, Osterman, A, Liddington, R.C.
登録日2004-12-18
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structure and lytic activity of a Bacillus anthracis prophage endolysin
J.Biol.Chem., 280, 2005
4RPI
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Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, nicotinate-nucleotide adenylyltransferase
著者Rodionova, I, Zuccola, H, Sorci, L, Aleshin, A.E, Kazanov, M, Sergienko, E, Rubin, E, Locher, C, Osterman, A.
登録日2014-10-30
公開日2015-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.417 Å)
主引用文献Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
J. Biol. Chem., 290, 2015
2AR3
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E90A mutant structure of PlyL
分子名称: PHOSPHATE ION, ZINC ION, prophage lambdaba02, ...
著者Low, L.Y, Yang, C, Perego, M, Osterman, A, Liddington, R.C.
登録日2005-08-19
公開日2006-06-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and lytic activity of a Bacillus anthracis prophage endolysin.
J.Biol.Chem., 280, 2005
5HM5
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Crystal structure of Topo-97, an N-terminal 97kDa fragment of topoisomerase V
分子名称: Topoisomerase V
著者Rajan, R, Osterman, A, Mondragon, A.
登録日2016-01-15
公開日2016-03-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Methanopyrus kandleri topoisomerase V contains three distinct AP lyase active sites in addition to the topoisomerase active site.
Nucleic Acids Res., 44, 2016
3FIU
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Structure of NMN synthetase from Francisella tularensis
分子名称: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase, ...
著者Sorci, L, Martynowski, D, Eyobo, Y, Osterman, A.L, Zhang, H.
登録日2008-12-12
公開日2009-03-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis
Proc.Natl.Acad.Sci.USA, 106, 2009
2R5W
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Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase from Francisella tularensis
分子名称: CHLORIDE ION, MAGNESIUM ION, Nicotinamide-nucleotide adenylyltransferase
著者Huang, N, Sorci, L, Zhang, X, Brautigan, C, Li, X, Raffaelli, N, Grishin, N, Osterman, A, Zhang, H.
登録日2007-09-04
公開日2008-03-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
2QJT
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Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase complexed with AMP and MN ion from Francisella tularensis
分子名称: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, Nicotinamide-nucleotide adenylyltransferase
著者Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H.
登録日2007-07-09
公開日2008-03-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
2QJO
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crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase (NadM) complexed with ADPRP and NAD from Synechocystis sp.
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Bifunctional NMN adenylyltransferase/Nudix hydrolase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H.
登録日2007-07-08
公開日2008-03-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
5TRD
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Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*TP*AP*CP*TP*AP*AP*TP*TP*CP*AP*CP*GP*AP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*TP*CP*GP*TP*GP*AP*AP*TP*TP*AP*GP*TP*AP*A)-3'), ...
著者Vetting, M.W, Rodionova, I.A, Li, X, Osterman, A.L, Rodionov, D.A, Almo, S.C.
登録日2016-10-26
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator
To be published
3Q1Q
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Structure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNA
分子名称: MAGNESIUM ION, PHOSPHATE ION, RNase P RNA, ...
著者Reiter, N.J, Osterman, A, Torres-Larios, A, Swinger, K.K, Pan, T, Mondragon, A.
登録日2010-12-17
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNA.
Nature, 468, 2010
1K4K
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Crystal structure of E. coli Nicotinic acid mononucleotide adenylyltransferase
分子名称: Nicotinic acid mononucleotide adenylyltransferase, XENON
著者Zhang, H, Zhou, T, Kurnasov, O, Cheek, S, Grishin, N.V, Osterman, A.L.
登録日2001-10-08
公開日2002-10-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD.
Structure, 10, 2002
6BUV
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Structure of Mycobacterium tuberculosis NadD in complex with inhibitor [(1~{R},2~{R},5~{S})-5-methyl-2-propan-2-yl-cyclohexyl] 2-[3-methyl-2-(phenoxymethyl)benzimidazol-1-yl]ethanoate
分子名称: 1-methyl-3-(2-{[(1R,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxoethyl)-2-(phenoxymethyl)-1H-1,3-benzimidazol-3-ium, CHLORIDE ION, SODIUM ION, ...
著者Rodionova, I.A, Reed, R.W, Sorci, L, Osterman, A.L, Korotkov, K.V.
登録日2017-12-11
公開日2018-12-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase.
Acs Chem.Biol., 14, 2019
2TOD
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ORNITHINE DECARBOXYLASE FROM TRYPANOSOMA BRUCEI K69A MUTANT IN COMPLEX WITH ALPHA-DIFLUOROMETHYLORNITHINE
分子名称: ALPHA-DIFLUOROMETHYLORNITHINE, PROTEIN (ORNITHINE DECARBOXYLASE), PYRIDOXAL-5'-PHOSPHATE
著者Grishin, N.V, Osterman, A.L, Brooks, H.B, Phillips, M.A, Goldsmith, E.J.
登録日1999-05-18
公開日1999-11-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine.
Biochemistry, 38, 1999

 

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