5IX3
 
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5B5W
 | | Crystal structure of MOB1-LATS1 NTR domain complex | | Descriptor: | MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ZINC ION | | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | | Deposit date: | 2016-05-24 | | Release date: | 2016-07-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.957 Å) | | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
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2K6Q
 | | LC3 p62 complex structure | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | | Authors: | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2008-07-17 | | Release date: | 2008-09-02 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
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2KWC
 | | The NMR structure of the autophagy-related protein Atg8 | | Descriptor: | Autophagy-related protein 8 | | Authors: | Kumeta, H, Watanabe, M, Nakatogawa, H, Yamaguchi, M, Ogura, K, Adachi, W, Fujioka, Y, Noda, N.N, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-05-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of the autophagy-related protein Atg8
J.Biomol.Nmr, 47, 2010
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8KCM
 | | MmCPDII-DNA complex containing low-dosage, light induced repaired DNA. | | Descriptor: | Deoxyribodipyrimidine photo-lyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Maestre-Reyna, M, Wang, P.-H, Nango, E, Hosokawa, Y, Saft, M, Furrer, A, Yang, C.-H, Ngura Putu, E.P.G, Wu, W.-J, Emmerich, H.-J, Engilberge, S, Caramello, N, Wranik, M, Glover, H.L, Franz-Badur, S, Wu, H.-Y, Lee, C.-C, Huang, W.-C, Huang, K.-F, Chang, Y.-K, Liao, J.-H, Weng, J.-H, Gad, W, Chang, C.-W, Pang, A.H, Gashi, D, Beale, E, Ozerov, D, Milne, C, Cirelli, C, Bacellar, C, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Spadaccini, R, Royant, A, Yamamoto, J, Iwata, S, Standfuss, J, Essen, L.-O, Bessho, Y, Tsai, M.-D. | | Deposit date: | 2023-08-08 | | Release date: | 2023-11-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Visualizing the DNA repair process by a photolyase at atomic resolution.
Science, 382, 2023
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7D36
 | | Crystal Structure of BACE1 in complex with N-{3-[(3S)-1-amino-5-fluoro-3-methyl-3,4-dihydro-2,6-naphthyridin-3-yl]-4-fluorophenyl}-5-cyano-3-methylpyridine-2-carboxamide | | Descriptor: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | | Authors: | Nakahara, K, Mitsuoka, Y, Kasuya, S, Yamamoto, T, Yamamoto, S, Ito, H, Kido, Y, Kusakabe, K.I. | | Deposit date: | 2020-09-18 | | Release date: | 2021-07-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Balancing potency and basicity by incorporating fluoropyridine moieties: Discovery of a 1-amino-3,4-dihydro-2,6-naphthyridine BACE1 inhibitor that affords robust and sustained central A beta reduction.
Eur.J.Med.Chem., 216, 2021
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5B5V
 | | Structure of full-length MOB1b | | Descriptor: | CHLORIDE ION, MOB kinase activator 1B, ZINC ION | | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | | Deposit date: | 2016-05-24 | | Release date: | 2016-07-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
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3VMZ
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3VMY
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5B6B
 | | Complex of LATS1 and phosphomimetic MOB1b | | Descriptor: | CHLORIDE ION, MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ... | | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | | Deposit date: | 2016-05-26 | | Release date: | 2016-07-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.536 Å) | | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
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3VN0
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3AWE
 | | Crystal structure of Pten-like domain of Ci-VSP (248-576) | | Descriptor: | ACETIC ACID, SODIUM ION, SULFATE ION, ... | | Authors: | Matsuda, M, Sakata, S, Takeshita, K, Suzuki, M, Yamashita, E, Okamura, Y, Nakagawa, A. | | Deposit date: | 2011-03-19 | | Release date: | 2011-05-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Crystal structure of the cytoplasmic phosphatase and tensin homolog (PTEN)-like region of Ciona intestinalis voltage-sensing phosphatase provides insight into substrate specificity and redox regulation of the phosphoinositide phosphatase activity
J.Biol.Chem., 286, 2011
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2CZO
 | | Solution Structure of the PX Domain of Bem1p | | Descriptor: | Bud emergence protein 1 | | Authors: | Maeda, A, Ogura, K, Horiuchi, M, Kumeta, H, Fujioka, Y, Inagaki, F. | | Deposit date: | 2005-07-14 | | Release date: | 2006-10-03 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the PX domain of Bem1p
To be Published
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3WH2
 | | Human Mincle in complex with citrate | | Descriptor: | C-type lectin domain family 4 member E, CALCIUM ION, CITRATE ANION | | Authors: | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | | Deposit date: | 2013-08-21 | | Release date: | 2013-10-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WHD
 | | C-type lectin, human MCL | | Descriptor: | C-type lectin domain family 4 member D, CALCIUM ION | | Authors: | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | | Deposit date: | 2013-08-24 | | Release date: | 2013-10-23 | | Last modified: | 2013-12-11 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
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3AWF
 | | Crystal structure of Pten-like domain of Ci-VSP (236-576) | | Descriptor: | GLYCEROL, SULFATE ION, Voltage-sensor containing phosphatase | | Authors: | Matsuda, M, Sakata, S, Takeshita, K, Suzuki, M, Yamashita, E, Okamura, Y, Nakagawa, A. | | Deposit date: | 2011-03-19 | | Release date: | 2011-05-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Crystal structure of the cytoplasmic phosphatase and tensin homolog (PTEN)-like region of Ciona intestinalis voltage-sensing phosphatase provides insight into substrate specificity and redox regulation of the phosphoinositide phosphatase activity
J.Biol.Chem., 286, 2011
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3WH3
 | | human Mincle, ligand free form | | Descriptor: | C-type lectin domain family 4 member E, CALCIUM ION | | Authors: | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | | Deposit date: | 2013-08-21 | | Release date: | 2013-10-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
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2LI5
 | | NMR structure of Atg8-Atg7C30 complex | | Descriptor: | Autophagy-related protein 8, Ubiquitin-like modifier-activating enzyme ATG7 | | Authors: | Kumeta, H, Satoo, K, Noda, N.N, Fujioka, Y, Ogura, K, Nakatogawa, H, Ohsumi, Y, Inagaki, F. | | Deposit date: | 2011-08-23 | | Release date: | 2011-11-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of Atg8 activation by a homodimeric E1, Atg7.
Mol.Cell, 44, 2011
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3AWG
 | | Crystal structure of Pten-like domain of Ci-VSP G356A mutant (248-576) | | Descriptor: | SULFATE ION, Voltage-sensor containing phosphatase | | Authors: | Matsuda, M, Sakata, S, Takeshita, K, Suzuki, M, Yamashita, E, Okamura, Y, Nakagawa, A. | | Deposit date: | 2011-03-19 | | Release date: | 2011-05-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Crystal structure of the cytoplasmic phosphatase and tensin homolog (PTEN)-like region of Ciona intestinalis voltage-sensing phosphatase provides insight into substrate specificity and redox regulation of the phosphoinositide phosphatase activity
J.Biol.Chem., 286, 2011
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4BGW
 | | Crystal Structure of H5 (VN1194) Influenza Haemagglutinin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Xiong, X, Coombs, P, Martin, S.R, Liu, J, Xiao, H, McCauley, J.W, Locher, K, Walker, P.A, Collins, P.J, Kawaoka, Y, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2013-03-29 | | Release date: | 2013-04-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus.
Nature, 497, 2013
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4BH3
 | | Haemagglutinin from a Transmissible Mutant H5 Influenza Virus in Complex with Human Receptor Analogue 6'-SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEMAGGLUTININ, ... | | Authors: | Xiong, X, Coombs, P.J, Martin, S.R, Liu, J, Xiao, H, McCauley, J.W, Locher, K, Walker, P.A, Collins, P.J, Kawaoka, Y, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2013-03-29 | | Release date: | 2013-04-24 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus
Nature, 497, 2013
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4BH4
 | | Haemagglutinin from a Transmissible Mutant H5 Influenza Virus in Complex with Avian Receptor Analogue 3'-SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEMAGGLUTININ, ... | | Authors: | Xiong, X, Coombs, P.J, Martin, S.R, Liu, J, Xiao, H, McCauley, J.W, Locher, K, Walker, P.A, Collins, P.J, Kawaoka, Y, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2013-03-29 | | Release date: | 2013-04-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus
Nature, 497, 2013
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4BH2
 | | Crystal Structure of the Haemagglutinin from a Transmissible Mutant H5 Influenza Virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEMAGGLUTININ, ... | | Authors: | Xiong, X, Coombs, P.J, Martin, S.R, Liu, J, Xiao, H, McCauley, J.W, Locher, K, Walker, P.A, Collins, P.J, Kawaoka, Y, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2013-03-29 | | Release date: | 2013-04-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus
Nature, 497, 2013
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4BGY
 | | H5 (VN1194) Influenza Virus Haemagglutinin in Complex with Avian Receptor Analogue 3'-SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEMAGGLUTININ, ... | | Authors: | Xiong, X, Coombs, P, Martin, S.R, Liu, J, Xiao, H, McCauley, J.W, Locher, K, Walker, P.A, Collins, P.J, Kawaoka, Y, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2013-03-29 | | Release date: | 2013-04-24 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus.
Nature, 497, 2013
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4BGX
 | | H5 (VN1194) Influenza Virus Haemagglutinin in Complex with Human Receptor Analogue 6'-SLN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEMAGGLUTININ, ... | | Authors: | Xiong, X, Coombs, P, Martin, S.R, Liu, J, Xiao, H, McCauley, J.W, Locher, K, Walker, P.A, Collins, P.J, Kawaoka, Y, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2013-03-29 | | Release date: | 2013-04-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Receptor Binding by a Ferret-Transmissible H5 Avian Influenza Virus.
Nature, 497, 2013
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