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PDB: 15 results

6WCB
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BU of 6wcb by Molmil
Human open state TMEM175 in CsCl
Descriptor: CESIUM ION, Endosomal/lysosomal potassium channel TMEM175
Authors:Oh, S, Paknejad, N, Hite, R.K.
Deposit date:2020-03-30
Release date:2020-04-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
8VIC
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BU of 8vic by Molmil
AP-6 bound human TMEM175
Descriptor: (2P,2'P)-2,2'-(1,3-phenylene)di(pyridin-4-amine), Endosomal/lysosomal potassium channel TMEM175
Authors:Oh, S, Hite, R.K.
Deposit date:2024-01-03
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structure of human TMEM175 in an inhibitor-bound state
To Be Published
8VIE
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BU of 8vie by Molmil
2-PPA bound human TMEM175
Descriptor: 2-phenylpyridin-4-amine, Endosomal/lysosomal potassium channel TMEM175
Authors:Oh, S, Hite, R.K.
Deposit date:2024-01-04
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structure of human TMEM175 in an inhibitor-bound state
To Be Published
7UNM
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BU of 7unm by Molmil
Human TMEM175 in an closed state
Descriptor: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
Authors:Oh, S, Hite, R.K.
Deposit date:2022-04-11
Release date:2022-06-29
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175.
Elife, 11, 2022
7UNL
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BU of 7unl by Molmil
Human TMEM175 in an open state
Descriptor: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
Authors:Oh, S, Hite, R.K.
Deposit date:2022-04-11
Release date:2022-06-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175.
Elife, 11, 2022
6WCA
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BU of 6wca by Molmil
Human closed state TMEM175 in KCl
Descriptor: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
Authors:Oh, S, Paknejad, N, Hite, R.K.
Deposit date:2020-03-30
Release date:2020-04-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
6WC9
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BU of 6wc9 by Molmil
Human open state TMEM175 in KCl
Descriptor: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
Authors:Oh, S, Paknejad, N, Hite, R.K.
Deposit date:2020-03-30
Release date:2020-04-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
6WCC
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BU of 6wcc by Molmil
Human closed state TMEM175 in CsCl
Descriptor: CESIUM ION, Endosomal/lysosomal potassium channel TMEM175
Authors:Oh, S, Paknejad, N, Hite, R.K.
Deposit date:2020-03-30
Release date:2020-04-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
8DHM
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BU of 8dhm by Molmil
Human TMEM175 in complex with 4-aminopyridine
Descriptor: 4-AMINOPYRIDINE, Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
Authors:Oh, S, Hite, R.K.
Deposit date:2022-06-27
Release date:2022-11-23
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175.
Proc.Natl.Acad.Sci.USA, 119, 2022
5UZ6
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BU of 5uz6 by Molmil
RNA hairpin structure containing 2-MeImp-oligo analogue
Descriptor: RNA (25-MER), RNA (5'-D(*(8OS))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
Authors:Zhang, W, Oh, S.S, Szostak, J.W.
Deposit date:2017-02-24
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5UX3
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BU of 5ux3 by Molmil
RNA hairpin structure containing 2-MeImpG monomer analogue and 2-MeImp-oligomer analogue
Descriptor: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-D(*(RG))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
Authors:Zhang, W, Oh, S.S, Szostak, J.W.
Deposit date:2017-02-21
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5CFY
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BU of 5cfy by Molmil
CRYSTAL STRUCTURE OF GLTPH R397A IN COMPLEX WITH NA+ AND L-ASP
Descriptor: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION
Authors:Boudker, O, Oh, S.
Deposit date:2015-07-08
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
4OYE
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BU of 4oye by Molmil
Crystal structure of GltPh R397A in apo
Descriptor: 425aa long hypothetical proton glutamate symport protein
Authors:Boudker, O, Oh, S.
Deposit date:2014-02-11
Release date:2014-09-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (4 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
4OYF
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BU of 4oyf by Molmil
Crystal structure of GLTPH R397A IN Sodium-bound state
Descriptor: GLUTAMATE SYMPORT PROTEIN, SODIUM ION
Authors:Boudker, O, Oh, S, Verdon, G, Serio, R.
Deposit date:2014-02-11
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
6CTF
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BU of 6ctf by Molmil
Crystal structure of GltPh fast mutant - R276S/M395R
Descriptor: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
Authors:Boudker, O, Oh, S.
Deposit date:2018-03-23
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh.
Elife, 7, 2018

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PDB entries from 2024-09-11

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