6WCA
 
 | | Human closed state TMEM175 in KCl | | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | | Authors: | Oh, S, Paknejad, N, Hite, R.K. | | Deposit date: | 2020-03-30 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
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6WC9
 | | Human open state TMEM175 in KCl | | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | | Authors: | Oh, S, Paknejad, N, Hite, R.K. | | Deposit date: | 2020-03-30 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
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6WCB
 | | Human open state TMEM175 in CsCl | | Descriptor: | CESIUM ION, Endosomal/lysosomal potassium channel TMEM175 | | Authors: | Oh, S, Paknejad, N, Hite, R.K. | | Deposit date: | 2020-03-30 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
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6WCC
 | | Human closed state TMEM175 in CsCl | | Descriptor: | CESIUM ION, Endosomal/lysosomal potassium channel TMEM175 | | Authors: | Oh, S, Paknejad, N, Hite, R.K. | | Deposit date: | 2020-03-30 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
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8VIC
 | | AP-6 bound human TMEM175 | | Descriptor: | (2P,2'P)-2,2'-(1,3-phenylene)di(pyridin-4-amine), Endosomal/lysosomal potassium channel TMEM175 | | Authors: | Oh, S, Hite, R.K. | | Deposit date: | 2024-01-03 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structure of human TMEM175 in an inhibitor-bound state
To Be Published
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8VIE
 | | 2-PPA bound human TMEM175 | | Descriptor: | 2-phenylpyridin-4-amine, Endosomal/lysosomal potassium channel TMEM175 | | Authors: | Oh, S, Hite, R.K. | | Deposit date: | 2024-01-04 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Structure of human TMEM175 in an inhibitor-bound state
To Be Published
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8DHM
 | | Human TMEM175 in complex with 4-aminopyridine | | Descriptor: | 4-AMINOPYRIDINE, Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | | Authors: | Oh, S, Hite, R.K. | | Deposit date: | 2022-06-27 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7UNM
 | | Human TMEM175 in an closed state | | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | | Authors: | Oh, S, Hite, R.K. | | Deposit date: | 2022-04-11 | | Release date: | 2022-06-29 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175.
Elife, 11, 2022
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7UNL
 | | Human TMEM175 in an open state | | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | | Authors: | Oh, S, Hite, R.K. | | Deposit date: | 2022-04-11 | | Release date: | 2022-06-01 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175.
Elife, 11, 2022
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7SI6
 | | Structure of ATP7B in state 1 | | Descriptor: | MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION | | Authors: | Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-16 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
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7SI7
 | | Structure of ATP7B in state 2 | | Descriptor: | MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION | | Authors: | Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-16 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
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7SI3
 | | Consensus structure of ATP7B | | Descriptor: | MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION | | Authors: | Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
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5K5V
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6CTF
 | | Crystal structure of GltPh fast mutant - R276S/M395R | | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | | Authors: | Boudker, O, Oh, S. | | Deposit date: | 2018-03-23 | | Release date: | 2018-10-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (4.05 Å) | | Cite: | Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh.
Elife, 7, 2018
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1E9Z
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1E9Y
 | | Crystal structure of Helicobacter pylori urease in complex with acetohydroxamic acid | | Descriptor: | ACETOHYDROXAMIC ACID, NICKEL (II) ION, UREASE SUBUNIT ALPHA, ... | | Authors: | Ha, N.-C, Oh, S.-T, Oh, B.-H. | | Deposit date: | 2000-11-01 | | Release date: | 2001-11-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Supramolecular Assembly and Acid Resistance of Helicobacter Pylori Urease
Nat.Struct.Biol., 8, 2001
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5HYY
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5K5U
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5K63
 | | Crystal structure of N-terminal amidase C187S | | Descriptor: | ASPARAGINE, GLYCINE, Nta1p | | Authors: | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | | Deposit date: | 2016-05-24 | | Release date: | 2017-01-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5K60
 | | Crystal structure of N-terminal amidase with Gln-Val peptide | | Descriptor: | GLUTAMINE, Nta1p, VALINE | | Authors: | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | | Deposit date: | 2016-05-24 | | Release date: | 2017-01-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5K66
 | | Crystal structure of N-terminal amidase with Asn-Glu peptide | | Descriptor: | ASPARAGINE, GLUTAMIC ACID, Nta1p | | Authors: | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | | Deposit date: | 2016-05-24 | | Release date: | 2017-01-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5K62
 | | Crystal structure of N-terminal amidase C187S | | Descriptor: | ASPARAGINE, Nta1p, VALINE | | Authors: | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | | Deposit date: | 2016-05-24 | | Release date: | 2017-01-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.899 Å) | | Cite: | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5K61
 | | Crystal structure of N-terminal amidase with Gln-Gly peptide | | Descriptor: | GLUTAMINE, Nta1p | | Authors: | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | | Deposit date: | 2016-05-24 | | Release date: | 2017-04-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5CFY
 | | CRYSTAL STRUCTURE OF GLTPH R397A IN COMPLEX WITH NA+ AND L-ASP | | Descriptor: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION | | Authors: | Boudker, O, Oh, S. | | Deposit date: | 2015-07-08 | | Release date: | 2016-04-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
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5B62
 | | Crystal structure of N-terminal amidase with Asn-Glu-Ala peptide | | Descriptor: | ASN-GLU-ALA, Nta1p | | Authors: | Kim, M.K, Oh, S.-J, Lee, B.-G, Song, H.K. | | Deposit date: | 2016-05-24 | | Release date: | 2017-01-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.042 Å) | | Cite: | Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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