7JGY
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7JHF
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7ABB
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5M9N
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![BU of 5m9n by Molmil](/molmil-images/mine/5m9n) | Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide | 分子名称: | 1,2-ETHANEDIOL, E2F peptide, N3, ... | 著者 | Tallant, C, Savitsky, P, Moehlenbrink, J, Chan, C, Nunez-Alonso, G, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Fedorov, O, La Thangue, N.B, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2016-11-01 | 公開日 | 2016-11-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically
dimethylated E2F peptide To Be Published
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5M9O
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![BU of 5m9o by Molmil](/molmil-images/mine/5m9o) | Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide | 分子名称: | E2F peptide, Staphylococcal nuclease domain-containing protein 1 | 著者 | Tallant, C, Savitsky, P, Moehlenbrink, J, Chan, C, Nunez-Alonso, G, Siejka, P, Sorrell, F.J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Fedorov, O, La Thangue, N.B, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2016-11-01 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically
dimethylated E2F peptide To Be Published
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8PE0
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![BU of 8pe0 by Molmil](/molmil-images/mine/8pe0) | X-ray structure of the Thermus thermophilus K167L mutant of the PilF-GSPIIB domain in the c-di-GMP bound state | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ... | 著者 | Neissner, K, Woehnert, J. | 登録日 | 2023-06-13 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | X-ray structure of the K167L mutant of PilF-GSPIIB domain in the c-di-GMP bound state To Be Published
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8PDK
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![BU of 8pdk by Molmil](/molmil-images/mine/8pdk) | X-ray structure of the Thermus thermophilus PilF-GSPIIB domain in the c-di-GMP bound state | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ... | 著者 | Neissner, K, Woehnert, J. | 登録日 | 2023-06-12 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structure of the PilF-GSPIIB domain in the c-di-GMP bound state To Be Published
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8PFA
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![BU of 8pfa by Molmil](/molmil-images/mine/8pfa) | X-ray structure of the Thermus thermophilus K167R mutant of the PilF-GSPIIB domain in the c-di-GMP bound state | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ... | 著者 | Neissner, K, Woehnert, J. | 登録日 | 2023-06-15 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray structure of the Thermus thermophilus K167R mutant of the PilF-GSPIIB domain in the c-di-GMP bound state To Be Published
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1ETJ
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![BU of 1etj by Molmil](/molmil-images/mine/1etj) | AZURIN MUTANT WITH MET 121 REPLACED BY GLU | 分子名称: | AZURIN, COPPER (II) ION | 著者 | Karlsson, B.G, Tsai, L.-C, Nar, H, Sanders-Loehr, J, Bonander, N, Langer, V, Sjolin, L. | 登録日 | 1997-01-11 | 公開日 | 1997-04-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray structure determination and characterization of the Pseudomonas aeruginosa azurin mutant Met121Glu. Biochemistry, 36, 1997
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7PD7
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![BU of 7pd7 by Molmil](/molmil-images/mine/7pd7) | Crocagin methyl transferase CgnL | 分子名称: | GLYCEROL, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Zheng, D, Koehnke, J. | 登録日 | 2021-08-04 | 公開日 | 2022-08-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nat.Chem., 15, 2023
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4ERK
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![BU of 4erk by Molmil](/molmil-images/mine/4erk) | THE COMPLEX STRUCTURE OF THE MAP KINASE ERK2/OLOMOUCINE | 分子名称: | EXTRACELLULAR REGULATED KINASE 2, OLOMOUCINE, SULFATE ION | 著者 | Wang, Z, Canagarajah, B, Boehm, J.C, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J. | 登録日 | 1998-07-09 | 公開日 | 1999-07-22 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of inhibitor selectivity in MAP kinases. Structure, 6, 1998
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6E69
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![BU of 6e69 by Molmil](/molmil-images/mine/6e69) | Ortho-substituted phenyl sulfonyl fluoride and fluorosulfate as potent elastase inhibitory fragments | 分子名称: | 2-(fluorosulfonyl)benzene-1-sulfonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wolan, D.W, Woehl, J.L, Kitamura, S. | 登録日 | 2018-07-24 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proc.Natl.Acad.Sci.USA, 116, 2019
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3RKF
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![BU of 3rkf by Molmil](/molmil-images/mine/3rkf) | Crystal structure of guanine riboswitch C61U/G37A double mutant bound to thio-guanine | 分子名称: | 2-amino-1,9-dihydro-6H-purine-6-thione, COBALT HEXAMMINE(III), Guanine riboswitch | 著者 | Buck, J, Wacker, A, Warkentin, E, Woehnert, J, Wirmer-Bartoschek, J, Schwalbe, H. | 登録日 | 2011-04-18 | 公開日 | 2011-08-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain. Nucleic Acids Res., 39, 2011
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3ELM
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![BU of 3elm by Molmil](/molmil-images/mine/3elm) | Crystal Structure of MMP-13 Complexed with Inhibitor 24f | 分子名称: | (2R)-({[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonyl}amino){1-[(1-methylethoxy)carbonyl]piperidin-4-yl}ethanoic acid, CALCIUM ION, Collagenase 3, ... | 著者 | Kulathila, R, Monovich, L, Koehn, J. | 登録日 | 2008-09-22 | 公開日 | 2009-07-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13 J.Med.Chem., 52, 2009
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2X5N
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![BU of 2x5n by Molmil](/molmil-images/mine/2x5n) | Crystal Structure of the SpRpn10 VWA domain | 分子名称: | 26S PROTEASOME REGULATORY SUBUNIT RPN10, SULFATE ION | 著者 | Riedinger, C, Boehringer, J, Trempe, J.-F, Lowe, E.D, Brown, N.R, Gehring, K, Noble, M.E.M, Gordon, C, Endicott, J.A. | 登録日 | 2010-02-10 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The Structure of Rpn10 and its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12. J.Biol.Chem., 285, 2010
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6UQD
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6TRP
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![BU of 6trp by Molmil](/molmil-images/mine/6trp) | Solution Structure of Docking Domain Complex of Pax NRPS: PaxC NDD - PaxB CDD | 分子名称: | Peptide synthetase XpsB,Peptide synthetase XpsB | 著者 | Watzel, J, Hacker, C, Duchardt-Ferner, E, Bode, H.B, Woehnert, J. | 登録日 | 2019-12-19 | 公開日 | 2020-08-12 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | A New Docking Domain Type in the Peptide-Antimicrobial-Xenorhabdus Peptide Producing Nonribosomal Peptide Synthetase fromXenorhabdus bovienii. Acs Chem.Biol., 15, 2020
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8CR7
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8CR3
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8CR4
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6EWU
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![BU of 6ewu by Molmil](/molmil-images/mine/6ewu) | Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12C-NDD | 分子名称: | NRPS Kj12C-NDD | 著者 | Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J. | 登録日 | 2017-11-06 | 公開日 | 2018-10-31 | 最終更新日 | 2024-06-19 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018
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5LWJ
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![BU of 5lwj by Molmil](/molmil-images/mine/5lwj) | Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa. | 分子名称: | GTP Class II RNA (34-MER), GUANOSINE-5'-TRIPHOSPHATE | 著者 | Wolter, A.C, Weickhmann, A.K, Nasiri, A.H, Hantke, K, Ohlenschlaeger, O, Wunderlich, C.H, Kreutz, C, Duchardt-Ferner, E, Woehnert, J. | 登録日 | 2016-09-17 | 公開日 | 2016-12-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer. Angew. Chem. Int. Ed. Engl., 56, 2017
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7ABA
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6EWS
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![BU of 6ews by Molmil](/molmil-images/mine/6ews) | Solution Structure of Rhabdopeptide NRPS Docking Domain Kj12A-NDD | 分子名称: | NRPS Kj12A-NDD | 著者 | Hacker, C, Cai, X, Kegler, C, Zhao, L, Weickhmann, A.K, Bode, H.B, Woehnert, J. | 登録日 | 2017-11-06 | 公開日 | 2018-10-31 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. Nat Commun, 9, 2018
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6SAZ
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![BU of 6saz by Molmil](/molmil-images/mine/6saz) | Cleaved human fetuin-b in complex with crayfish astacin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Astacin, ... | 著者 | Gomis-Ruth, F.X, Guevara, T, Cuppari, A, Korschgen, H, Schmitz, C, Kuske, M, Yiallouros, I, Floehr, J, Jahnen-Dechent, W, Stocker, W. | 登録日 | 2019-07-18 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases. Sci Rep, 9, 2019
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