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PDB: 1 results

3KSL
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BU of 3ksl by Molmil
Structure of FPT bound to DATFP-DH-GPP
Descriptor: (2S,6E)-8-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}-2,6-dimethyloct-6-en-1-yl (2S)-3,3,3-trifluoro-2-hydrazinopropanoate, Farnesyltransferase, CAAX box, ...
Authors:Hovlid, M.L, Edelstein, R.L, Henry, O, Ochocki, J, DeGraw, A, Lenevich, S, Talbot, T, Young, V, Hruza, A.W, Lopez-Gallego, F, Labello, N.P, Strickland, C.L, Schmidt-Dannert, C, Distefano, M.D.
Deposit date:2009-11-23
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability.
Chem.Biol.Drug Des., 75, 2010

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