4DN3
 
 | | Crystal structure of anti-mcp-1 antibody cnto888 | | 分子名称: | CNTO888 HEAVY CHAIN, CNTO888 LIGHT CHAIN | | 著者 | Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. | | 登録日 | 2012-02-08 | | 公開日 | 2012-10-03 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
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4DN4
 | | Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a | | 分子名称: | ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ... | | 著者 | Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. | | 登録日 | 2012-02-08 | | 公開日 | 2012-10-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
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1EWR
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1EWQ
 | | CRYSTAL STRUCTURE TAQ MUTS COMPLEXED WITH A HETERODUPLEX DNA AT 2.2 A RESOLUTION | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3'), ... | | 著者 | Obmolova, G, Ban, C, Hsieh, P, Yang, W. | | 登録日 | 2000-04-26 | | 公開日 | 2000-10-23 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
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1JJV
 | | DEPHOSPHO-COA KINASE IN COMPLEX WITH ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DEPHOSPHO-COA KINASE, MERCURY (II) ION, ... | | 著者 | Obmolova, G, Teplyakov, A, Bonander, N, Eisenstein, E, Howard, A.J, Gilliland, G.L, Structure 2 Function Project (S2F) | | 登録日 | 2001-07-09 | | 公開日 | 2002-05-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of dephospho-coenzyme A kinase from Haemophilus influenzae.
J.Struct.Biol., 136, 2001
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1LQA
 | | TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH | | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Tas protein | | 著者 | Obmolova, G, Teplyakov, A, Khil, P.P, Howard, A.J, Camerini-Otero, R.D, Gilliland, G.L, Structure 2 Function Project (S2F) | | 登録日 | 2002-05-09 | | 公開日 | 2003-07-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | | 主引用文献 | Crystal structure of the Escherichia coli Tas protein, an NADP(H)-dependent aldo-keto reductase
PROTEINS: STRUCT.,FUNCT.,GENET., 53, 2003
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3O11
 | | Anti-beta-amyloid antibody c706 fab in space group c2 | | 分子名称: | C706 HEAVY CHAIN variable region, Ig gamma-1 chain C region chimera, C706 LIGHT CHAIN variable region, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | 登録日 | 2010-07-20 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | His-tag binding by antibody C706 mimics beta-amyloid recognition.
J.Mol.Recognit., 24, 2011
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4YDY
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4YDW
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6AL5
 | | COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B-lymphocyte antigen CD19, B43 HEAVY CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2017-08-07 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of B-cell co-receptor CD19 in complex with antibody B43 reveals an unexpected fold.
Proteins, 86, 2018
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6AL4
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5KNG
 | | CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9 | | 分子名称: | DARPIN 6G9, GLYCEROL, PHOSPHATE ION | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G. | | 登録日 | 2016-06-28 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
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5KNH
 | | CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13 | | 分子名称: | ACETATE ION, DARPIN 6G9, IL13 | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G. | | 登録日 | 2016-06-28 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
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4HAG
 | | Crystal structure of fc-fragment of human IgG2 antibody (centered crystal form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2 chain C region | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Zhao, Y, Gilliland, G. | | 登録日 | 2012-09-26 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface.
Mol.Immunol., 56, 2013
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4HAF
 | | Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2 chain C region | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Zhao, Y, Gilliland, G. | | 登録日 | 2012-09-26 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface.
Mol.Immunol., 56, 2013
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6CNV
 | | INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab heavy chain, ... | | 著者 | Luo, J, Obmolova, G. | | 登録日 | 2018-03-09 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
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1MOS
 | | ISOMERASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH 2-AMINO-2-DEOXYGLUCITOL 6-PHOSPHATE | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, GLUCOSAMINE 6-PHOSPHATE SYNTHASE, ... | | 著者 | Teplyakov, A, Obmolova, G, Badet-Denisot, M.A, Badet, B. | | 登録日 | 1998-07-15 | | 公開日 | 1999-07-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase.
Protein Sci., 8, 1999
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4M7L
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4LPY
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4LPU
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4LPV
 | | Crystal structure of TENCON variant P41BR3-42 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TENCON variant P41BR3-42 | | 著者 | Teplyakov, A, Obmolova, G, Luo, J, Gilliland, G.L. | | 登録日 | 2013-07-16 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
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4M6N
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4LPT
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4M6A
 | | N-Terminal beta-Strand Swapping in a Consensus Derived Alternative Scaffold Driven by Stabilizing Hydrophobic Interactions | | 分子名称: | Tencon | | 著者 | Luo, J, Teplyakov, A, Obmolova, G, Malia, T.J, Chan, W, Jocobs, S.A, O'neil, K.T, Gilliland, G.L. | | 登録日 | 2013-08-09 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | N-terminal beta-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions.
Proteins, 82, 2014
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4M6O
 | | Crystal structure of anti-NGF antibody CNTO7309 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO7309 heavy chain, CNTO7309 light chain, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | 登録日 | 2013-08-09 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
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