1VYB
 
 | | Endonuclease domain of human LINE1 ORF2p | | 分子名称: | GLYCEROL, ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN, SULFATE ION, ... | | 著者 | Weichenrieder, O, Repanas, K, Perrakis, A. | | 登録日 | 2004-04-25 | | 公開日 | 2004-06-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon.
Structure, 12, 2004
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8CCI
 | | Crystal structure of Mycobacterium smegmatis thioredoxin reductase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Fuesser, F.T, Koch, O, Kuemmel, D. | | 登録日 | 2023-01-27 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Novel starting points for fragment-based drug design against mycobacterial thioredoxin reductase identified using crystallographic fragment screening.
Acta Crystallogr D Struct Biol, 79, 2023
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1QPY
 | | CRYSTAL STRUCTURE OF BACKBONE MODIFIED PNA HEXAMER | | 分子名称: | PEPTIDE NUCLEIC ACID 5'-(*CP1*GPN*TP1*APN*CP1*GPN*LYS)-3' | | 著者 | Haima, G, Rasmussen, H, Schmidt, G, Jensen, D.K, Kastrup, J.S, Stafshede, P.W, Norden, B, Buchardt, O, Nielsen, P.E. | | 登録日 | 1999-05-14 | | 公開日 | 2001-02-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Peptide Nucleic Acids (PNA) derived from N-(N-methylaminoethyl)glycine. Synthesis, hybridization and structural properties
New J.Chem., 23, 1999
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1QXN
 | | Solution Structure of the 30 kDa Polysulfide-sulfur Transferase Homodimer from Wolinella Succinogenes | | 分子名称: | PENTASULFIDE-SULFUR, sulfide dehydrogenase | | 著者 | Lin, Y.J, Dancea, F, Loehr, F, Klimmek, O, Pfeiffer-Marek, S, Nilges, M, Wienk, H, Kroeger, A, Rueterjans, H. | | 登録日 | 2003-09-08 | | 公開日 | 2004-02-24 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the 30 kDa Polysulfide-Sulfur Transferase Homodimer from Wolinella succinogenes
Biochemistry, 43, 2004
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1QX6
 | | Crystal structure of Sortase B complexed with E-64 | | 分子名称: | N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, NPQTN specific sortase B | | 著者 | Zong, Y, Mazmanian, S.K, Schneewind, O, Narayana, S.V. | | 登録日 | 2003-09-04 | | 公開日 | 2004-04-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall
Structure, 12, 2004
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1QXD
 | | Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds | | 分子名称: | FURFURAL, Hemoglobin alpha chain, Hemoglobin beta chain, ... | | 著者 | Safo, M.K, Abdulmalik, O, Danso-Danquah, R, Nokuri, S, Joshi, G.S, Musayev, F.N, Asakura, T, Abraham, D.J. | | 登録日 | 2003-09-05 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds
J.Med.Chem., 47, 2004
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1VDR
 | | DIHYDROFOLATE REDUCTASE | | 分子名称: | DIHYDROFOLATE REDUCTASE, PHOSPHATE ION | | 著者 | Pieper, U, Herzberg, O. | | 登録日 | 1997-11-30 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii.
Structure, 6, 1998
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3TQ5
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8C09
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8C0A
 | | Crystal structure of JAK2 JH2-R683S | | 分子名称: | 3,5-diphenyl-2-(trifluoromethyl)-1~{H}-pyrazolo[1,5-a]pyrimidin-7-one, GLYCEROL, Tyrosine-protein kinase JAK2 | | 著者 | Haikarainen, T, Silvennoinen, O. | | 登録日 | 2022-12-16 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling.
Sci Adv, 10, 2024
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1NQJ
 | | CRYSTAL STRUCTURE OF CLOSTRIDIUM HISTOLYTICUM COLG COLLAGENASE COLLAGEN-BINDING DOMAIN 3B AT 1.0 ANGSTROM RESOLUTION IN ABSENCE OF CALCIUM | | 分子名称: | CHLORIDE ION, LITHIUM ION, class 1 collagenase | | 著者 | Wilson, J.J, Matsushita, O, Okabe, A, Sakon, J. | | 登録日 | 2003-01-21 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | A bacterial collagen-binding domain with novel calcium-binding motif
controls domain orientation
Embo J., 22, 2003
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1OB2
 | | E. coli elongation factor EF-Tu complexed with the antibiotic kirromycin, a GTP analog, and Phe-tRNA | | 分子名称: | ELONGATION FACTOR TU, KIRROMYCIN, MAGNESIUM ION, ... | | 著者 | Kristensen, O, Nissen, P, Nyborg, J. | | 登録日 | 2003-01-24 | | 公開日 | 2004-05-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Kirromycin Defines a Specific Domain Arrangement of Elongation Factor EF-TU
To be Published
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1QXE
 | | Structural Basis for the Potent Antisickling Effect of a Novel Class of 5-Membered Heterocyclic Aldehydic Compounds | | 分子名称: | 5-HYDROXYMETHYL-FURFURAL, Hemoglobin alpha chain, Hemoglobin beta chain, ... | | 著者 | Safo, M.K, Abdulmalik, O, Danso-Danquah, R, Nokuri, S, Joshi, G.S, Musayev, F.N, Asakura, T, Abraham, D.J. | | 登録日 | 2003-09-05 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds
J.Med.Chem., 47, 2004
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1QXA
 | | Crystal structure of Sortase B complexed with Gly3 | | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, NPQTN specific sortase B, peptide GLY-GLY-GLY | | 著者 | Zong, Y, Mazmanian, S.K, Schneewind, O, Narayana, S.V. | | 登録日 | 2003-09-05 | | 公開日 | 2004-04-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall
Structure, 12, 2004
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8EW3
 | | Cryo EM structure of Vibrio cholerae NQR | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit A, ... | | 著者 | Fuller, J.R, Juarez, O. | | 登録日 | 2022-10-21 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (2.65159 Å) | | 主引用文献 | Novel cofactor binding motifs, electron transfer and ion pumping mechanisms of the respiratory complex NQR
To Be Published
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8EVU
 | | Cryo EM structure of Vibrio cholerae NQR | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit A, ... | | 著者 | Fuller, J.R, Juarez, O. | | 登録日 | 2022-10-20 | | 公開日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (2.5804 Å) | | 主引用文献 | Novel cofactor binding motifs, electron transfer and ion pumping mechanisms of the respiratory complex NQR
To Be Published
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3TS6
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1VC3
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1V2X
 | | TrmH | | 分子名称: | PHOSPHATE ION, S-ADENOSYLMETHIONINE, tRNA (Gm18) methyltransferase | | 著者 | Nureki, O, Watanabe, K, Fukai, S, Ishii, R, Endo, Y, Hori, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-10-17 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
STRUCTURE, 12, 2004
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1QJH
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1QDB
 | | CYTOCHROME C NITRITE REDUCTASE | | 分子名称: | CALCIUM ION, CYTOCHROME C NITRITE REDUCTASE, HEME C, ... | | 著者 | Einsle, O, Messerschmidt, A, Stach, P, Huber, R, Kroneck, P.M.H. | | 登録日 | 1999-05-19 | | 公開日 | 1999-08-18 | | 最終更新日 | 2021-03-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of cytochrome c nitrite reductase.
Nature, 400, 1999
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8CQW
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Hygromycin B | | 分子名称: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-07 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
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8CAS
 | | Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2023-01-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
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8CBJ
 | | Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex | | 分子名称: | 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... | | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2023-01-25 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
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8CQ7
 | | Crystal structure of phyllanthoside bound to the Candida albicans 80S ribosome | | 分子名称: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-03 | | 公開日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
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