2L0T
 
 | | Solution structure of the complex of ubiquitin and the VHS domain of Stam2 | | 分子名称: | Signal transducing adapter molecule 2, Ubiquitin | | 著者 | Lange, A, Hoeller, D, Wienk, H, Marcillat, O, Lancelin, J, Walker, O. | | 登録日 | 2010-07-15 | | 公開日 | 2010-12-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin.
Biochemistry, 50, 2011
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7U28
 | | Structure of SARS-CoV-2 Mpro Lambda (G15S) in complex with Nirmatrelvir (PF-07321332) | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | | 著者 | Greasley, S.E, Ferre, R.A, Plotnikova, O, Liu, W, Stewart, A.E. | | 登録日 | 2022-02-23 | | 公開日 | 2022-03-09 | | 最終更新日 | 2022-06-15 | | 実験手法 | X-RAY DIFFRACTION (1.679 Å) | | 主引用文献 | Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants.
J.Biol.Chem., 298, 2022
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2JC6
 | | Crystal structure of human calmodulin-dependent protein kinase 1D | | 分子名称: | CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE | | 著者 | Debreczeni, J.E, Rellos, P, Fedorov, O, Niesen, F.H, Bhatia, C, Shrestha, L, Salah, E, Smee, C, Colebrook, S, Berridge, G, Gileadi, O, Bunkoczi, G, Ugochukwu, E, Pike, A.C.W, von Delft, F, Knapp, S, Sundstrom, M, Weigelt, J, Arrowsmith, C.H, Edwards, A. | | 登録日 | 2006-12-19 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published
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8A9Q
 | | Computational design of stable mammalian serum albumins for bacterial expression | | 分子名称: | Albumin, LAURIC ACID, MYRISTIC ACID, ... | | 著者 | Khersonsky, O, Dym, O, Fleishman, J.S. | | 登録日 | 2022-06-29 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Stable Mammalian Serum Albumins Designed for Bacterial Expression.
J.Mol.Biol., 435, 2023
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2IZR
 | | Structure of casein kinase gamma 3 in complex with inhibitor | | 分子名称: | CASEIN KINASE I ISOFORM GAMMA-3, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. | | 登録日 | 2006-07-26 | | 公開日 | 2006-08-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Inhibitor Binding by Casein Kinases
To be Published
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2IZU
 | | Structure of casein kinase gamma 3 in complex with inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, CASEIN KINASE I ISOFORM GAMMA-3, ... | | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. | | 登録日 | 2006-07-26 | | 公開日 | 2006-08-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Inhibitor Binding by Casein Kinases
To be Published
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2IZT
 | | Structure of casein kinase gamma 3 in complex with inhibitor | | 分子名称: | CASEIN KINASE I ISOFORM GAMMA-3, CHLORIDE ION, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE | | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. | | 登録日 | 2006-07-26 | | 公開日 | 2006-08-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inhibitor Binding by Casein Kinases
To be Published
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2K2M
 | | Structural Basis of PxxDY Motif Recognition in SH3 Binding | | 分子名称: | Eps8-like protein 1 | | 著者 | Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Saksela, K, Permi, P. | | 登録日 | 2008-04-02 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of PxxDY motif recognition in SH3 binding.
J.Mol.Biol., 382, 2008
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4ZNB
 | | METALLO-BETA-LACTAMASE (C181S MUTANT) | | 分子名称: | METALLO-BETA-LACTAMASE, SODIUM ION, ZINC ION | | 著者 | Li, Z, Herzberg, O. | | 登録日 | 1998-10-20 | | 公開日 | 1999-06-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural consequences of the active site substitution Cys181 --> Ser in metallo-beta-lactamase from Bacteroides fragilis.
Protein Sci., 8, 1999
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2KDG
 | | Solution Structure of the 1st Ig domain of Myotilin | | 分子名称: | Myotilin | | 著者 | Heikkinen, O, Kilpelainen, I, Permi, P, Koskela, H, Ylanne, J, Carpen, O. | | 登録日 | 2009-01-08 | | 公開日 | 2009-07-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the first immunoglobulin domain of human myotilin
J.Biomol.Nmr, 44, 2009
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1MW2
 | | Amylosucrase soaked with 100mM sucrose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, amylosucrase, ... | | 著者 | Skov, L.K, Mirza, O, Sprogoe, D, Dar, I, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | | 登録日 | 2002-09-27 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
J.BIOL.CHEM., 277, 2002
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1MW3
 | | Amylosucrase soaked with 1M sucrose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, amylosucrase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Skov, L.K, Mirza, O, Sprogoe, D, Dar, I, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | | 登録日 | 2002-09-27 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
J.BIOL.CHEM., 277, 2002
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2QDS
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1MVY
 | | Amylosucrase mutant E328Q co-crystallized with maltoheptaose. | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | Skov, L.K, Mirza, O, Sprogoe, D, Dar, I, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | | 登録日 | 2002-09-27 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
J.BIOL.CHEM., 277, 2002
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1MW1
 | | Amylosucrase soaked with 14mM sucrose. | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, amylosucrase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Skov, L.K, Mirza, O, Sprogoe, D, Dar, I, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | | 登録日 | 2002-09-27 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
J.BIOL.CHEM., 277, 2002
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4JNW
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2CBZ
 | | Structure of the human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 | | 著者 | Ramaen, O, Leulliot, N, Sizun, C, Ulryck, N, Pamlard, O, Lallemand, J.-Y, van Tilbeurgh, H, Jacquet, E. | | 登録日 | 2006-01-10 | | 公開日 | 2006-05-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the Human Multidrug Resistance Protein 1 Nucleotide Binding Domain 1 Bound to Mg(2+)/ATP Reveals a Non-Productive Catalytic Site.
J.Mol.Biol., 359, 2006
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4IIA
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2CHL
 | | Structure of casein kinase 1 gamma 3 | | 分子名称: | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, CASEIN KINASE I ISOFORM GAMMA-3, SULFATE ION | | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Ugochukwu, E, Weigelt, J, von Delft, F, Knapp, S. | | 登録日 | 2006-03-15 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of Casein Kinase 1 Gamma 3
To be Published
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1N77
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and ATP. | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-11-13 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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2G0N
 | | The Crystal Structure of the Human RAC3 in complex with GDP and Chloride | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) | | 登録日 | 2006-02-13 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
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4O38
 | | Crystal structure of the human cyclin G associated kinase (GAK) | | 分子名称: | Cyclin-G-associated kinase, GLYCEROL, SUCCINIC ACID | | 著者 | Zhang, R, Hatzos-Skintges, C, Weger, A, Chaikuad, A, Eswaran, J, Fedorov, O, King, O, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structural Genomics Consortium (SGC) | | 登録日 | 2013-12-18 | | 公開日 | 2014-01-01 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Crystal structure of the human cyclin G associated kinase (GAK)
To be Published
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2B5R
 | | 1B Lactamase / B Lactamase Inhibitor | | 分子名称: | Beta-lactamase TEM, Beta-lactamase inhibitory protein | | 著者 | Rahat, O, Albeck, S, Meged, R, Dym, O, Screiber, G, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2005-09-29 | | 公開日 | 2006-04-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
J.Mol.Biol., 102, 2006
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2FFS
 | | Structure of PR10-allergen-like protein PA1206 from Pseudomonas aeruginosa PAO1 | | 分子名称: | hypothetical protein PA1206 | | 著者 | Zimmerman, M.D, Chruszcz, M, Cymborowski, M.T, Wang, S, Kirillova, O, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-12-20 | | 公開日 | 2006-01-10 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of PR10-Allergen-Like Protein PA1206 From Pseudomonas aeruginosa PAO1
To be Published
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2C5W
 | | PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE | | 分子名称: | 1,2-ETHANEDIOL, CEFOTAXIME, C3' cleaved, ... | | 著者 | Contreras-Martel, C, Job, V, Di Guilmi, A.-M, Vernet, T, Dideberg, O, Dessen, A. | | 登録日 | 2005-11-02 | | 公開日 | 2005-12-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
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