1GLN
 
 | | ARCHITECTURES OF CLASS-DEFINING AND SPECIFIC DOMAINS OF GLUTAMYL-TRNA SYNTHETASE | | 分子名称: | GLUTAMYL-TRNA SYNTHETASE | | 著者 | Nureki, O, Vassylyev, D.G, Katayanagi, K, Shimizu, T, Sekine, S, Kigawa, T, Miyazawa, T, Yokoyama, S, Morikawa, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1994-07-20 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Architectures of class-defining and specific domains of glutamyl-tRNA synthetase.
Science, 267, 1995
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1UET
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1UEU
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1V2X
 | | TrmH | | 分子名称: | PHOSPHATE ION, S-ADENOSYLMETHIONINE, tRNA (Gm18) methyltransferase | | 著者 | Nureki, O, Watanabe, K, Fukai, S, Ishii, R, Endo, Y, Hori, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-10-17 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Deep Knot Structure for Construction of Active Site and Cofactor Binding Site of tRNA Modification Enzyme
STRUCTURE, 12, 2004
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1UEV
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1IPA
 | | CRYSTAL STRUCTURE OF RNA 2'-O RIBOSE METHYLTRANSFERASE | | 分子名称: | RNA 2'-O-RIBOSE METHYLTRANSFERASE | | 著者 | Nureki, O, Shirouzu, M, Hashimoto, K, Ishitani, R, Terada, T, Tamakoshi, M, Oshima, T, Chijimatsu, M, Takio, K, Vassylyev, D.G, Shibata, T, Inoue, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2001-05-02 | | 公開日 | 2002-07-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | An enzyme with a deep trefoil knot for the active-site architecture.
Acta Crystallogr.,Sect.D, 58, 2002
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1IRX
 | | Crystal structure of class I lysyl-tRNA synthetase | | 分子名称: | ZINC ION, lysyl-tRNA synthetase | | 著者 | Nureki, O, Terada, T, Ishitani, R, Ambrogelly, A, Ibba, M, Soll, D, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2001-10-25 | | 公開日 | 2002-04-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Functional convergence of two lysyl-tRNA synthetases with unrelated topologies.
Nat.Struct.Biol., 9, 2002
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1ILE
 | | ISOLEUCYL-TRNA SYNTHETASE | | 分子名称: | ISOLEUCYL-TRNA SYNTHETASE, ZINC ION | | 著者 | Nureki, O, Vassylyev, D.G, Tateno, M, Shimada, A, Nakama, T, Fukai, S, Konno, M, Schimmel, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1998-02-24 | | 公開日 | 1999-04-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enzyme structure with two catalytic sites for double-sieve selection of substrate.
Science, 280, 1998
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2D6F
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3AII
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2ZY9
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7XJI
 | | Solabegron-activated dog beta3 adrenergic receptor | | 分子名称: | 3-[3-[2-[[(2~{S})-2-(3-chlorophenyl)-2-oxidanyl-ethyl]amino]ethylamino]phenyl]benzoic acid, Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Shihoya, W, Nureki, O. | | 登録日 | 2022-04-18 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures of the beta 3 adrenergic receptor bound to solabegron and isoproterenol.
Biochem.Biophys.Res.Commun., 611, 2022
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7XJH
 | | Isoproterenol-activated dog beta3 adrenergic receptor | | 分子名称: | Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Shihoya, W, Nureki, O. | | 登録日 | 2022-04-18 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity.
Mol.Cell, 81, 2021
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3UG9
 | | Crystal Structure of the Closed State of Channelrhodopsin | | 分子名称: | Archaeal-type opsin 1, Archaeal-type opsin 2, OLEIC ACID, ... | | 著者 | Kato, H.E, Ishitani, R, Nureki, O. | | 登録日 | 2011-11-02 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the channelrhodopsin light-gated cation channel
Nature, 482, 2012
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8YNY
 | | Structure of Cas9-sgRNA ribonucleoprotein bound to nucleosome | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (17-mer), DNA (175-mer), ... | | 著者 | Nagamura, R, Kujirai, T, Kusakizako, T, Hirano, H, Kurumizaka, H, Nureki, O. | | 登録日 | 2024-03-12 | | 公開日 | 2025-01-22 | | 実験手法 | ELECTRON MICROSCOPY (4.52 Å) | | 主引用文献 | Structural insights into how Cas9 targets nucleosomes.
Nat Commun, 15, 2024
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8ZTU
 | | 70S ribosome arrested by PepNL | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Ando, Y, Kobo, A, Nureki, O, Taguchi, H, Itoh, Y, Chadani, Y. | | 登録日 | 2024-06-07 | | 公開日 | 2025-03-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism.
Nat Commun, 16, 2025
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8ZTV
 | | 70S ribosome arrested by PepNL with RF2 | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Ando, Y, Kobo, A, Nureki, O, Taguchi, H, Itoh, Y, Chadani, Y. | | 登録日 | 2024-06-07 | | 公開日 | 2025-03-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism.
Nat Commun, 16, 2025
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3UG0
 | | Crystal structure of a Trp-less green fluorescent protein translated by the simplified genetic code | | 分子名称: | Green fluorescent protein | | 著者 | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | | 登録日 | 2011-11-02 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | | 主引用文献 | Simplification of the genetic code: restricted diversity of genetically encoded amino acids.
Nucleic Acids Res., 40, 2012
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3HJ7
 | | Crystal structure of TILS C-terminal domain | | 分子名称: | CHLORIDE ION, tRNA(Ile)-lysidine synthase | | 著者 | Nakanishi, K, Bonnefond, L, Kimura, S, Suzuki, T, Ishitani, R, Nureki, O. | | 登録日 | 2009-05-21 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase.
Nature, 461, 2009
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3UFZ
 | | Crystal structure of a Trp-less green fluorescent protein translated by the universal genetic code | | 分子名称: | Green fluorescent protein | | 著者 | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | | 登録日 | 2011-11-02 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Simplification of the genetic code: restricted diversity of genetically encoded amino acids.
Nucleic Acids Res., 40, 2012
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1N75
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP. | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION | | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-11-12 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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1N77
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and ATP. | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-11-13 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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9JTQ
 | | Crystal structure of the light-driven proton pump heimdallarchaeial rhodopsin HeimdallR1 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, NITRATE ION, RETINAL, ... | | 著者 | Matsuzaki, Y, Tzlil, G, Del Carmen Marin, M, Shihoya, W, Beja, O, Nureki, O. | | 登録日 | 2024-10-06 | | 公開日 | 2025-04-02 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Light-harvesting by antenna-containing rhodopsins in pelagic Asgard archaea
To Be Published
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1N78
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP. | | 分子名称: | GLUTAMOL-AMP, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-11-13 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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6LMT
 | | Cryo-EM structure of the killifish CALHM1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Calcium homeostasis modulator 1 | | 著者 | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2019-12-26 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
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