1CLK
 
 | | CRYSTAL STRUCTURE OF STREPTOMYCES DIASTATICUS NO.7 STRAIN M1033 XYLOSE ISOMERASE AT 1.9 A RESOLUTION WITH PSEUDO-I222 SPACE GROUP | | Descriptor: | COBALT (II) ION, MAGNESIUM ION, XYLOSE ISOMERASE | | Authors: | Niu, L, Teng, M, Zhu, X, Gong, W. | | Deposit date: | 1999-04-29 | | Release date: | 2000-05-03 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of xylose isomerase from Streptomyces diastaticus no. 7 strain M1033 at 1.85 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
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7F7W
 | | JAK2-JH2 | | Descriptor: | 2-((1-(2-fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl)(methyl)amino)ethan-1-ol, Tyrosine-protein kinase JAK2 | | Authors: | Niu, L. | | Deposit date: | 2021-06-30 | | Release date: | 2022-03-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2 V617F -induced myeloproliferative neoplasms.
Blood Cancer J, 12, 2022
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1QT1
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1QUA
 | | CRYSTAL STRUCTURE OF ACUTOLYSIN-C, A HEMORRHAGIC TOXIN FROM THE SNAKE VENOM OF AGKISTRODON ACUTUS, AT 2.2 A RESOLUTION | | Descriptor: | ACUTOLYSIN-C, ZINC ION | | Authors: | Niu, L, Teng, M, Zhu, X. | | Deposit date: | 1999-06-30 | | Release date: | 2000-07-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of acutolysin-C, a haemorrhagic toxin from the venom of Agkistrodon acutus, providing further evidence for the mechanism of the pH-dependent proteolytic reaction of zinc metalloproteinases.
Acta Crystallogr.,Sect.D, 55, 1999
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4HWZ
 | | Structure of HLA-A68 complexed with an HIV derived peptide | | Descriptor: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-09 | | Release date: | 2013-10-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4I48
 | | Structure of HLA-A68 complexed with an HIV Env derived peptide | | Descriptor: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-27 | | Release date: | 2013-10-02 | | Method: | X-RAY DIFFRACTION (2.799 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4HX1
 | | Structure of HLA-A68 complexed with a tumor antigen derived peptide | | Descriptor: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-09 | | Release date: | 2013-10-02 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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5HXW
 | | L-amino acid deaminase from Proteus vulgaris | | Descriptor: | CETYL-TRIMETHYL-AMMONIUM, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid deaminase | | Authors: | Zhou, H, Ju, Y, Niu, L, Teng, M. | | Deposit date: | 2016-01-31 | | Release date: | 2016-08-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
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5I39
 | | High resolution structure of L-amino acid deaminase from Proteus vulgaris with the deletion of the specific insertion sequence | | Descriptor: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid deaminase | | Authors: | Zhou, H, Ju, Y, Niu, L, Teng, M. | | Deposit date: | 2016-02-10 | | Release date: | 2016-08-03 | | Last modified: | 2016-08-24 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
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3MNM
 | | Crystal structure of GAE domain of GGA2p from Saccharomyces cerevisiae | | Descriptor: | ADP-ribosylation factor-binding protein GGA2, GLYCEROL, SULFATE ION | | Authors: | Fang, P, Wang, J, Li, X, Niu, L, Teng, M. | | Deposit date: | 2010-04-21 | | Release date: | 2010-09-08 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Structural basis for the specificity of the GAE domain of yGGA2 for its accessory proteins Ent3 and Ent5
Biochemistry, 49, 2010
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3MD3
 | | Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1) | | Descriptor: | GLYCEROL, Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1, SULFATE ION | | Authors: | Li, H, Shi, H, Zhu, Z, Wang, H, Niu, L, Teng, M. | | Deposit date: | 2010-03-29 | | Release date: | 2010-05-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)
To be published
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3MIL
 | | Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae | | Descriptor: | GLYCEROL, Isoamyl acetate-hydrolyzing esterase | | Authors: | Ma, J, Lu, Q, Yuan, Y, Li, K, Ge, H, Go, Y, Niu, L, Teng, M. | | Deposit date: | 2010-04-11 | | Release date: | 2010-11-24 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae reveals a novel active site architecture and the basis of substrate specificity
Proteins, 79, 2011
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6XFQ
 | | Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor | | Descriptor: | Platelet glycoprotein Ib alpha chain, Snaclec agglucetin subunit alpha-1, Snaclec agglucetin subunit beta-2 | | Authors: | Wang, J, Gao, Y.X, Ke, J.Y, Zhu, Z.L, Niu, L.W. | | Deposit date: | 2020-06-16 | | Release date: | 2021-06-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of a novel antithrombotic agent Agkisacucetin in complex with the platelet glycoprotein Ib receptor
To be published
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1XX5
 | | Crystal Structure of Natrin from Naja atra snake venom | | Descriptor: | ETHANOL, Natrin 1 | | Authors: | Wang, J, Shen, B, Lou, X.H, Guo, M, Teng, M.K, Niu, L.W. | | Deposit date: | 2004-11-04 | | Release date: | 2005-06-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Blocking effect and crystal structure of natrin toxin, a cysteine-rich secretory protein from Naja atra venom that targets the BKCa channel
Biochemistry, 44, 2005
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1MC2
 | | monomeric LYS-49 phospholipase A2 homologue purified from AG | | Descriptor: | Acutohaemonlysin, ISOPROPYL ALCOHOL | | Authors: | Liu, Q, Huang, Q.Q, Zhang, R.G, Weeks, C.M, Jelsch, C, Teng, M.K, Niu, L.W. | | Deposit date: | 2002-08-05 | | Release date: | 2002-08-21 | | Last modified: | 2018-02-14 | | Method: | X-RAY DIFFRACTION (0.85 Å) | | Cite: | The crystal structure of a novel, inactive, lysine 49 PLA2 from Agkistrodon acutus venom: an ultrahigh resolution, AB initio structure determination
J.Biol.Chem., 278, 2003
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1OP0
 | | Crystal Structure of AaV-SP-I, a Glycosylated Snake Venom Serine Proteinase from Agkistrodon acutus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Venom serine proteinase | | Authors: | Zhu, Z, Teng, M, Niu, L. | | Deposit date: | 2003-03-04 | | Release date: | 2004-05-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures and Amidolytic Activities of Two Glycosylated Snake Venom Serine Proteinases
J.BIOL.CHEM., 280, 2005
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1BSW
 | | ACUTOLYSIN A FROM SNAKE VENOM OF AGKISTRODON ACUTUS AT PH 7.5 | | Descriptor: | CALCIUM ION, PROTEIN (ACUTOLYSIN A), ZINC ION | | Authors: | Gong, W, Zhu, X, Liu, S, Teng, M, Niu, L. | | Deposit date: | 1998-08-31 | | Release date: | 1999-08-26 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus.
J.Mol.Biol., 283, 1998
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1BUD
 | | ACUTOLYSIN A FROM SNAKE VENOM OF AGKISTRODON ACUTUS AT PH 5.0 | | Descriptor: | CALCIUM ION, PROTEIN (ACUTOLYSIN A), ZINC ION | | Authors: | Gong, W, Zhu, X, Liu, S, Teng, M, Niu, L. | | Deposit date: | 1998-09-03 | | Release date: | 1999-09-07 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus.
J.Mol.Biol., 283, 1998
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8YT5
 | | SP1746 treated with EDTA, in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, bis(5'-nucleosyl)-tetraphosphatase (symmetrical) | | Authors: | Jin, Y, Niu, L, Ke, J. | | Deposit date: | 2024-03-25 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia.
Structure, 2024
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1OP2
 | | Crystal Structure of AaV-SP-II, a Glycosylated Snake Venom Serine Proteinase from Agkistrodon acutus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Venom serine proteinase | | Authors: | Zhu, Z, Teng, M, Niu, L. | | Deposit date: | 2003-03-04 | | Release date: | 2004-05-25 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures and Amidolytic Activities of Two Glycosylated Snake Venom Serine Proteinases
J.BIOL.CHEM., 280, 2005
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1MG6
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4ZN3
 | | Crystal Structure of MjSpt4:Spt5 complex conformation B | | Descriptor: | FE (III) ION, GLYCEROL, Transcription elongation factor Spt4, ... | | Authors: | Guo, G.R, Zhou, H.H, Gao, Y.X, Zhu, Z.L, Niu, L.W, Teng, M.K. | | Deposit date: | 2015-05-04 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII
J.Struct.Biol., 192, 2015
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4ZN1
 | | Crystal Structure of MjSpt4:Spt5 complex conformation A | | Descriptor: | Transcription elongation factor Spt4, Transcription elongation factor Spt5, ZINC ION | | Authors: | Guo, G.R, Zhou, H.H, Gao, Y.X, Zhu, Z.L, Niu, L.W, Teng, M.K. | | Deposit date: | 2015-05-04 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII
J.Struct.Biol., 192, 2015
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1WT9
 | | crystal structure of Aa-X-bp-I, a snake venom protein with the activity of binding to coagulation factor X from Agkistrodon acutus | | Descriptor: | CALCIUM ION, agkisacutacin A chain, anticoagulant protein-B | | Authors: | Zhu, Z, Liu, S, Mo, X, Yu, X, Liang, Z, Zang, J, Zhao, W, Teng, M, Niu, L. | | Deposit date: | 2004-11-18 | | Release date: | 2006-03-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Characterizations and Crystal structures of two snake venom proteins with the activity of binding coagulation factor X from Agkistrodon acutus
To be Published
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3B9C
 | | Crystal Structure of Human GRP CRD | | Descriptor: | BETA-MERCAPTOETHANOL, HSPC159, SULFATE ION | | Authors: | Zhou, D, Ge, H.H, Niu, L.W, Teng, M.K. | | Deposit date: | 2007-11-05 | | Release date: | 2008-03-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins.
Proteins, 71, 2008
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