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PDB: 161 件
1R80
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Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, MERCURY (II) ION, ...
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R81
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Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate-N-acetyl-galactose
分子名称: Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MERCURY (II) ION, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, ...
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1Q9K
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S25-2 Fab Unliganded 1
分子名称: MAGNESIUM ION, S25-2 Fab (IgG1k) heavy chain, S25-2 Fab (IgG1k) light chain
著者Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
登録日2003-08-25
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
1R7V
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BU of 1r7v by Molmil
Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor
分子名称: Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-amino-3-deoxy-beta-D-galactopyranoside
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
6TZ9
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CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B only
分子名称: Charged multivesicular body protein 1b
著者Nguyen, H.C, Frost, A.
登録日2019-08-11
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ4
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CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (right-handed)
分子名称: Charged multivesicular body protein 1b, IST1 homolog
著者Nguyen, H.C, Frost, A.
登録日2019-08-10
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZA
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CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant
分子名称: IST1 homolog
著者Nguyen, H.C, Frost, A.
登録日2019-08-11
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ5
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CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (left-handed)
分子名称: Charged multivesicular body protein 1b, IST1 homolog
著者Nguyen, H.C, Frost, A.
登録日2019-08-10
公開日2020-04-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
5F52
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Erwinia chrysanthemi L-asparaginase + Aspartic acid
分子名称: ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, L-asparaginase
著者Nguyen, H.A, Lavie, A.
登録日2015-12-04
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Insight into Substrate Selectivity of Erwinia chrysanthemi l-Asparaginase.
Biochemistry, 55, 2016
3L8E
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Crystal Structure of apo form of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli
分子名称: ACETIC ACID, D,D-heptose 1,7-bisphosphate phosphatase, ZINC ION
著者Nguyen, H, Peisach, E, Allen, K.N.
登録日2009-12-31
公開日2010-02-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
3L8F
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Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with magnesium and phosphate
分子名称: D,D-heptose 1,7-bisphosphate phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Nguyen, H, Peisach, E, Allen, K.N.
登録日2009-12-31
公開日2010-02-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
5K4H
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BU of 5k4h by Molmil
Wolinella succinogenes L-asparaginase S121 + L-Glutamic acid
分子名称: GLUTAMIC ACID, L-asparaginase
著者Nguyen, H.A, Lave, A.
登録日2016-05-20
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
3L8G
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BU of 3l8g by Molmil
Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with D-glycero-D-manno-heptose 1 ,7-bisphosphate
分子名称: 1,7-di-O-phosphono-L-glycero-beta-D-manno-heptopyranose, D,D-heptose 1,7-bisphosphate phosphatase, MAGNESIUM ION, ...
著者Nguyen, H, Peisach, E, Allen, K.N.
登録日2009-12-31
公開日2010-02-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
3L8H
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Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from B. bronchiseptica complexed with magnesium and phosphate
分子名称: FORMIC ACID, MAGNESIUM ION, PHOSPHATE ION, ...
著者Nguyen, H, Peisach, E, Allen, K.N.
登録日2009-12-31
公開日2010-02-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
5K4G
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BU of 5k4g by Molmil
Wolinella succinogenes L-asparaginase S121 + L-aspartic acid, open conformation
分子名称: ASPARTIC ACID, L-asparaginase
著者Nguyen, H.A, Lave, A.
登録日2016-05-20
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
4WUY
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BU of 4wuy by Molmil
Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor
分子名称: 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ...
著者Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M.
登録日2014-11-04
公開日2015-04-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
J.Biol.Chem., 290, 2015
6NDK
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BU of 6ndk by Molmil
Structure of ASLSufA6 A37.5 bound to the 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.T, Hoffer, E.D, Dunham, C.M.
登録日2018-12-13
公開日2019-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Importance of a tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing intRNACGGProfor decoding
J. Biol. Chem., 294, 2019
6O81
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Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to translation initiation factor 2 from Homo sapiens
分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Nguyen, H, Kenner, L, Frost, A.
登録日2019-03-08
公開日2019-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
4WQO
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Structure of VHL-EloB-EloC-Cul2
分子名称: Cullin-2, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ...
著者Nguyen, H.C, Xiong, Y.
登録日2014-10-22
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
Structure, 23, 2015
1R7Y
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BU of 1r7y by Molmil
Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate
分子名称: Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, MERCURY (II) ION, ...
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
1R7T
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BU of 1r7t by Molmil
Glycosyltransferase A in complex with 3-deoxy-acceptor analog inhibitor
分子名称: Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
6O85
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BU of 6o85 by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
分子名称: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Nguyen, H.C, Kenner, L.R, Frost, A.S.
登録日2019-03-08
公開日2019-05-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
1R7X
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BU of 1r7x by Molmil
Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-amino-3-deoxy-beta-D-galactopyranoside
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
6O9Z
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BU of 6o9z by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ...
著者Nguyen, H.C, Kenner, L.R, Frost, A.S.
登録日2019-03-15
公開日2019-05-15
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
1R7U
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BU of 1r7u by Molmil
Glycosyltransferase B in complex with 3-deoxy-acceptor analog inhibitor
分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside
著者Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V.
登録日2003-10-22
公開日2004-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003

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