1R80

Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate

Summary for 1R80

• Entry DOI: 10.2210/pdb1r80/pdb
• Related: 1R7T 1R7U 1R7V 1R7X 1R7Y 1R81 1R82
• Descriptor: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, alpha-L-fucopyranose-(1-2)-hexyl 3-amino-3-deoxy-beta-D-galactopyranoside, MERCURY (II) ION, ... (6 entities in total)
• Functional Keywords: glycoprotein, transmembrane, signal-anchor, blood group antigen, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
• Total number of polymer chains: 1
• Total formula weight: 34431.44

Authors

Nguyen, H.P.,Seto, N.O.L.,Cai, Y.,Leinala, E.K.,Borisova, S.N.,Palcic, M.M.,Evans, S.V. (deposition date: 2003-10-22, release date: 2004-02-10, Last modification date: 2022-12-21)

• Primary citation: Nguyen, H.P.,Seto, N.O.L.,Cai, Y.,Leinala, E.K.,Borisova, S.N.,Palcic, M.M.,Evans, S.V.; The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases; J.Biol.Chem., 278:49191-49195, 2003; PubMed: 12972418; DOI: 10.1074/jbc.M308770200

Experimental method

X-RAY DIFFRACTION (1.65 Å)