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PDB: 5 件
7DD1
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BU of 7dd1 by Molmil
Crystal structure of SRPK1 in complex with a peptide inhibitor
分子名称: ARG-GLU-ARG-ALA-ARG-THR-ARG, SRSF protein kinase 1,SRSF protein kinase 1
著者Li, Q.Y, Yung, K.W.Y, Ngo, J.C.K.
登録日2020-10-27
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Protein-Protein Interaction Inhibitor of SRPKs Alters the Splicing Isoforms of VEGF and Inhibits Angiogenesis.
Iscience, 24, 2021
7VFT
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BU of 7vft by Molmil
Crystal structure of rGGGC(CAG)5GUCC oligo
分子名称: RNA (5'-R(*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3')
著者An, Y, Chan, H.Y.E, Ngo, J.C.K.
登録日2021-09-13
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases.
Nucleic Acids Res., 50, 2022
5XV7
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BU of 5xv7 by Molmil
SRPK1 in complex with Alectinib
分子名称: 1,2-ETHANEDIOL, 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, serine-arginine (SR) protein kinase 1
著者Zeng, C, Ngo, J.C.K.
登録日2017-06-26
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform
Cell Chem Biol, 25, 2018
6ITU
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BU of 6itu by Molmil
Crystal Structure of the GULP1 PTB domain-APP peptide complex
分子名称: 1,2-ETHANEDIOL, Amyloid beta A4 protein, PTB domain-containing engulfment adapter protein 1, ...
著者Yung, K.W.Y, Lau, K.F, Ngo, J.C.K.
登録日2018-11-26
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Attenuation of amyloid-beta generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35.
Faseb J., 33, 2019
5HGG
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BU of 5hgg by Molmil
Crystal structure of uPA in complex with a camelid-derived antibody fragment
分子名称: (3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Camelid Derived Antibody Fragment, ...
著者Yung, K.W.Y, Kromann-Hansen, T, Andreasen, P.A, Ngo, J.C.K.
登録日2016-01-08
公開日2016-06-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior
J.Biol.Chem., 291, 2016

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件を2024-10-30に公開中

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