3PM3
| Bovine trypsin variant X(tripleIle227) in complex with small molecule inhibitor | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | 登録日 | 2010-11-16 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
|
|
3PLB
| Bovine trypsin variant X(tripleIle227) in complex with small molecule inhibitor | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | 登録日 | 2010-11-15 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
|
|
3PLP
| Bovine trypsin variant X(tripleIle227) in complex with small molecule inhibitor | 分子名称: | 2,7-BIS-(4-AMIDINOBENZYLIDENE)-CYCLOHEPTAN-1-ONE, CALCIUM ION, Cationic trypsin, ... | 著者 | Tziridis, A, Neumann, P, Braeuer, U, Kolenko, P, Stubbs, M.T. | 登録日 | 2010-11-15 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
|
|
3PLK
| Bovine trypsin variant X(tripleIle227) in complex with small molecule inhibitor | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | 著者 | Tziridis, A, Neumann, P, Braeuer, U, Kolenko, P, Stubbs, M.T. | 登録日 | 2010-11-15 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
|
|
3PWB
| Bovine trypsin variant X(tripleGlu217Ile227) in complex with small molecule inhibitor | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. | 登録日 | 2010-12-08 | 公開日 | 2011-12-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
|
|
6YJ8
| DarB-APO | 分子名称: | ACETATE ION, CBS domain-containing protein YkuL, DI(HYDROXYETHYL)ETHER | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | 登録日 | 2020-04-02 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | DarB from B. subtilis To Be Published
|
|
6YJ9
| DarB in complex with 3'3'cGAMP | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CBS domain-containing protein YkuL, CHLORIDE ION | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | 登録日 | 2020-04-02 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | DarB from B. subtilis To Be Published
|
|
6YJ7
| |
6YJA
| DarB fom B. subtilis in complex with c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, CBS domain-containing protein YkuL, ... | 著者 | Heidemann, J.L, Neumann, P, Ficner, R. | 登録日 | 2020-04-02 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | DarB from B. subtilis To Be Published
|
|
3C3Y
| Crystal Structure of PFOMT, Phenylpropanoid and Flavonoid O-methyltransferase from M. crystallinum | 分子名称: | CALCIUM ION, O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Kopycki, J.G, Rauh, D, Neumann, P, Stubbs, M.T. | 登録日 | 2008-01-29 | 公開日 | 2008-04-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.371 Å) | 主引用文献 | Biochemical and Structural Analysis of Substrate Promiscuity in Plant Mg(2+)-Dependent O-Methyltransferases J.Mol.Biol., 378, 2008
|
|
3CGM
| Crystal structure of thermophilic SlyD | 分子名称: | GLYCEROL, NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase, ... | 著者 | Loew, C, Neumann, P, Stubbs, M.T, Balbach, J. | 登録日 | 2008-03-06 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus J.Mol.Biol., 398, 2010
|
|
4HZK
| |
4IA5
| Hydratase from Lactobacillus acidophilus - SeMet derivative (apo LAH) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Khoshnevis, S, Neumann, P, Ficner, R. | 登録日 | 2012-12-06 | 公開日 | 2013-03-27 | 最終更新日 | 2013-08-07 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Crystal structure analysis of a fatty acid double-bond hydratase from Lactobacillus acidophilus Acta Crystallogr.,Sect.D, 69, 2013
|
|
4IA6
| Hydratase from lactobacillus acidophilus in a ligand bound form (LA LAH) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Khoshnevis, S, Neumann, P, Ficner, R. | 登録日 | 2012-12-06 | 公開日 | 2013-03-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure analysis of a fatty acid double-bond hydratase from Lactobacillus acidophilus Acta Crystallogr.,Sect.D, 69, 2013
|
|
1KGI
| Rat transthyretin (also called prealbumin) complex with 3,3',5,5'-tetraiodothyroacetic acid (t4ac) | 分子名称: | 3,3',5,5'-TETRAIODOTHYROACETIC ACID, TRANSTHYRETIN | 著者 | Wojtczak, A, Neumann, P, Muziol, T, Cody, V, Luft, J.R, Pangborn, W. | 登録日 | 2001-11-27 | 公開日 | 2002-11-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Complex of rat transthyretin with tetraiodothyroacetic acid refined at 2.1 and 1.8 A resolution. Acta Biochim.Pol., 48, 2001
|
|
3E07
| Crystal structure of spatzle cystine knot | 分子名称: | GLYCEROL, Protein spaetzle | 著者 | Hoffmann, A, Funkner, A, Neumann, P, Juhnke, S, Walther, M, Schierhorn, A, Weininger, U, Balbach, J, Reuter, G, Stubbs, M.T. | 登録日 | 2008-07-31 | 公開日 | 2008-09-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Biophysical Characterization of Refolded Drosophila Spatzle, a Cystine Knot Protein, Reveals Distinct Properties of Three Isoforms J.Biol.Chem., 283, 2008
|
|
1KGJ
| Rat transthyretin (also called prealbumin) complex with 3',5'-dibromoflavone (EMD21388) | 分子名称: | 6,4'-DIHYDROXY-3-METHYL-3',5'-DIBROMOFLAVONE, TRANSTHYRETIN | 著者 | Wojtczak, A, Neumann, P, Muziol, T, Cody, V, Luft, J.R, Pangborn, W. | 登録日 | 2001-11-27 | 公開日 | 2002-11-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Comparison of binding interactions of dibromoflavonoids with transthyretin. Acta Biochim.Pol., 48, 2001
|
|
3E7W
| Crystal structure of DLTA: Implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains | 分子名称: | ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1, PHOSPHATE ION | 著者 | Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T. | 登録日 | 2008-08-19 | 公開日 | 2008-09-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains J.Biol.Chem., 283, 2008
|
|
3E7X
| Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains | 分子名称: | ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1 | 著者 | Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T. | 登録日 | 2008-08-19 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains J.Biol.Chem., 283, 2008
|
|
3EY6
| Crystal structure of the FK506-binding domain of human FKBP38 | 分子名称: | FK506-binding protein 8 | 著者 | Parthier, C, Maestre-Martinez, M, Neumann, P, Edlich, F, Fischer, G, Luecke, C, Stubbs, M.T. | 登録日 | 2008-10-19 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding. J.Mol.Recognit., 24, 2011
|
|
4JQ9
| Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex | 分子名称: | CHLORIDE ION, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Tietzel, M, Neumann, P, Meyer, D, Ficner, R, Tittmann, K. | 登録日 | 2013-03-20 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex TO BE PUBLISHED
|
|
3GJX
| Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP | 分子名称: | CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... | 著者 | Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R. | 登録日 | 2009-03-09 | 公開日 | 2009-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP. Science, 2009
|
|
5EK8
| Crystal structure of a 9R-lipoxygenase from Cyanothece PCC8801 at 2.7 Angstroms | 分子名称: | FE (II) ION, Lipoxygenase, SODIUM ION | 著者 | Feussner, I, Ficner, R, Neumann, P, Newie, J, Andreou, A, Einsle, O. | 登録日 | 2015-11-03 | 公開日 | 2015-12-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition. J.Lipid Res., 57, 2016
|
|
4B2A
| Structure of the factor Xa-like trypsin variant triple-Ala (TGA) in complex with eglin C | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | 登録日 | 2012-07-13 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
|
|
4B2B
| Structure of the factor Xa-like trypsin variant triple-Ala (TGPA) in complex with eglin C | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | 登録日 | 2012-07-13 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
|
|