3O57
 
 | | Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor | | 分子名称: | 5-[5-benzyl-4-(2-oxo-2-pyrrolidin-1-ylethyl)-1,3-oxazol-2-yl]-1-ethyl-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine, ARSENIC, GLYCEROL, ... | | 著者 | Somers, D.O, Neu, M. | | 登録日 | 2010-07-28 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR.
Bioorg.Med.Chem.Lett., 20, 2010
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3O56
 | | Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor | | 分子名称: | 1-ethyl-5-[3-(2-oxo-2-pyrrolidin-1-ylethyl)-1,2,4-oxadiazol-5-yl]-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine, ARSENIC, GLYCEROL, ... | | 著者 | Somers, D.O, Neu, M. | | 登録日 | 2010-07-28 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR.
Bioorg.Med.Chem.Lett., 20, 2010
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1H76
 | | The crystal structure of diferric porcine serum transferrin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | 著者 | Hall, D.R, Hadden, J.M, Leonard, G.A, Bailey, S, Neu, M, Winn, M, Lindley, P.F. | | 登録日 | 2001-07-03 | | 公開日 | 2002-01-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The Crystal and Molecular Structures of Diferric Porcine and Rabbit Serum Transferrins at Resolutions of 2.15 And 2.60A, Respectively
Acta Crystallogr.,Sect.D, 58, 2002
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1GVC
 | | 18kDa N-II domain fragment of duck ovotransferrin + NTA | | 分子名称: | CARBONATE ION, FE (III) ION, NITRILOTRIACETIC ACID, ... | | 著者 | Kuser, P, Hall, D.R, Haw, M.L, Neu, M, Lindley, P.F. | | 登録日 | 2002-02-07 | | 公開日 | 2002-02-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Mechanism of Iron Uptake by Transferrins: The X-Ray Structures of the 18 kDa Nii Domain Fragment of Duck Ovotransferrin and its Nitrilotriacetate Complex
Acta Crystallogr.,Sect.D, 58, 2002
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1GV8
 | | 18 kDa fragment of N-II domain of duck ovotransferrin | | 分子名称: | CARBONATE ION, FE (III) ION, GLYCINE, ... | | 著者 | Kuser, P, Hall, D.R, Haw, M.L, Neu, M, Lindley, P.F. | | 登録日 | 2002-02-07 | | 公開日 | 2002-02-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Mechanism of Iron Uptake by Transferrins: The X-Ray Structures of the 18 kDa Nii Domain Fragment of Duck Ovotransferrin and its Nitrilotriacetate Complex
Acta Crystallogr.,Sect.D, 58, 2002
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1IHC
 | | X-ray Structure of Gephyrin N-terminal Domain | | 分子名称: | Gephyrin | | 著者 | Sola, M, Kneussel, M, Heck, I.S, Betz, H, Weissenhorn, W. | | 登録日 | 2001-04-21 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray crystal structure of the trimeric N-terminal domain of gephyrin.
J.Biol.Chem., 276, 2001
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1D1N
 | | SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2 | | 分子名称: | INITIATION FACTOR 2 | | 著者 | Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M. | | 登録日 | 1999-09-20 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
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1DXM
 | | Reduced form of the H protein from glycine decarboxylase complex | | 分子名称: | DIHYDROLIPOIC ACID, H PROTEIN | | 著者 | Faure, M, Cohen-Addad, C, Neuburger, M, Douce, R. | | 登録日 | 2000-01-10 | | 公開日 | 2000-07-04 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Interaction between the Lipoamide-Containing H-Protein and the Lipoamide Dehydrogenase (L-Protein) of the Glycine Decarboxylase Multienzyme System. 2. Crystal Structure of H- and L-Proteins
Eur.J.Biochem., 267, 2000
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1DXL
 | | Dihydrolipoamide dehydrogenase of glycine decarboxylase from Pisum Sativum | | 分子名称: | DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Faure, M, Cohen-Addad, C, Bourguignon, J, Macherel, D, Neuburger, M, Douce, R. | | 登録日 | 2000-01-10 | | 公開日 | 2000-07-20 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Interaction between the Lipoamide-Containing H-Protein and the Lipoamide Dehydrogenase (L-Protein) of the Glycine Decarboxylase Multienzyme System. 2. Crystal Structure of H- and L-Proteins
Eur.J.Biochem., 267, 2000
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1CMR
 | | NMR SOLUTION STRUCTURE OF A CHIMERIC PROTEIN, DESIGNED BY TRANSFERRING A FUNCTIONAL SNAKE BETA-HAIRPIN INTO A SCORPION ALPHA/BETA SCAFFOLD (PH 3.5, 20C), NMR, 18 STRUCTURES | | 分子名称: | CHARYBDOTOXIN, ALPHA CHIMERA | | 著者 | Zinn-Justin, S, Guenneugues, M, Drakopoulou, E, Gilquin, B, Vita, C, Menez, A. | | 登録日 | 1996-03-15 | | 公開日 | 1996-08-01 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Transfer of a beta-hairpin from the functional site of snake curaremimetic toxins to the alpha/beta scaffold of scorpion toxins: three-dimensional solution structure of the chimeric protein.
Biochemistry, 35, 1996
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1KCP
 | | 3D STRUCTURE OF K-CONOTOXIN PVIIA, A NOVEL POTASSIUM CHANNEL-BLOCKING TOXIN FROM CONE SNAILS, NMR, 22 STRUCTURES | | 分子名称: | KAPPA-CONOTOXIN PVIIA | | 著者 | Savarin, P, Guenneugues, M, Gilquin, B, Lamthanh, H, Gasparini, S, Zinn-Justin, S, Menez, A. | | 登録日 | 1998-01-27 | | 公開日 | 1998-10-14 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails.
Biochemistry, 37, 1998
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1KJT
 | | Crystal Structure of the GABA(A) Receptor Associated Protein, GABARAP | | 分子名称: | GABARAP, NICKEL (II) ION, SODIUM ION | | 著者 | Bavro, V.N, Sola, M, Bracher, A, Kneussel, M, Betz, H, Weissenhorn, W. | | 登録日 | 2001-12-05 | | 公開日 | 2002-04-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the GABA(A)-receptor-associated protein, GABARAP.
EMBO Rep., 3, 2002
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1P0A
 | | NMR structure of ETD135, mutant of the antifungal defensin ARD1 from Archaeoprepona demophon | | 分子名称: | DEFENSIN ARD1 | | 著者 | Landon, C, Guenneugues, M, Barbault, F, Legrain, M, Menin, L, Schott, V, Vovelle, F, Dimarcq, J.L. | | 登録日 | 2003-04-10 | | 公開日 | 2004-03-09 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lead optimization of antifungal peptides with 3D NMR structures analysis.
Protein Sci., 13, 2004
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1OZZ
 | | NMR structure of antifungal defensin ARD1 from Archaeoprepona demophon | | 分子名称: | defensin ARD1 | | 著者 | Landon, C, Guenneugues, M, Barbault, F, Legrain, M, Menin, L, Schott, V, Vovelle, F, Dimarcq, J.L. | | 登録日 | 2003-04-10 | | 公開日 | 2004-03-09 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lead optimization of antifungal peptides with 3D NMR structures analysis.
Protein Sci., 13, 2004
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1P00
 | | NMR structure of ETD151, mutant of the antifungal defensin ARD1 from Archaeoprepona demophon | | 分子名称: | defensin ARD1 | | 著者 | Landon, C, Guenneugues, M, Barbault, F, Legrain, M, Menin, L, Schott, V, Vovelle, F, Dimarcq, J.L. | | 登録日 | 2003-04-10 | | 公開日 | 2004-03-09 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Lead optimization of antifungal peptides with 3D NMR structures analysis.
Protein Sci., 13, 2004
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1Q3J
 | | Solution structure of ALO3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus | | 分子名称: | ALO3 | | 著者 | Barbault, F, Landon, C, Guenneugues, M, Meyer, J.P, Schott, V, Dimarrcq, J.L, Vovelle, F. | | 登録日 | 2003-07-30 | | 公開日 | 2003-12-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus.
Biochemistry, 42, 2003
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4IIK
 | | Legionella pneumophila effector | | 分子名称: | Adenosine monophosphate-protein hydrolase SidD, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tascon, I, Chen, Y, Neunuebel, M.R, Rojas, A.L, Machner, M.P, Hierro, A. | | 登録日 | 2012-12-20 | | 公開日 | 2013-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD
Plos Pathog., 9, 2013
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4IIP
 | | Legionella pneumophila effector | | 分子名称: | Adenosine monophosphate-protein hydrolase SidD, CHLORIDE ION, GLYCEROL | | 著者 | Tascon, I, Chen, Y, Neunuebel, M.R, Rojas, A.L, Machner, M.P, Hierro, A. | | 登録日 | 2012-12-20 | | 公開日 | 2013-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD
Plos Pathog., 9, 2013
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7JSD
 | | Hydroxylase homolog of BesD with Fe(II), alpha-ketoglutarate, and lysine | | 分子名称: | 2-OXOGLUTARIC ACID, FE (II) ION, LYSINE, ... | | 著者 | Kissman, E.N, Neugebauer, M.E, Chang, M.C.Y. | | 登録日 | 2020-08-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Reaction pathway engineering converts a radical hydroxylase into a halogenase.
Nat.Chem.Biol., 18, 2022
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8CIZ
 | | DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Mycoplanecin A. | | 分子名称: | Beta sliding clamp, Mycoplanecin A | | 著者 | Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. | | 登録日 | 2023-02-11 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
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8CIY
 | | DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Cyclohexyl-Griselimycin. | | 分子名称: | ACETATE ION, Beta sliding clamp, CALCIUM ION, ... | | 著者 | Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. | | 登録日 | 2023-02-11 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
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8CIX
 | | DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin. | | 分子名称: | ACETATE ION, Beta sliding clamp, CALCIUM ION, ... | | 著者 | Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. | | 登録日 | 2023-02-11 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins.
Nat Commun, 15, 2024
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7U6J
 | | HalB with lysine and succinate | | 分子名称: | Halogenase B, LYSINE, SUCCINIC ACID | | 著者 | Sumida, K.H, Neugebauer, M.E, Kissman, E.N, Chang, M.C.Y. | | 登録日 | 2022-03-04 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7U6H
 | | HalD with ornithine and alpha-ketoglutarate | | 分子名称: | 2-OXOGLUTARIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Swenson, C.V, Neugebauer, M.E, Kissman, E.N, Chang, M.C.Y. | | 登録日 | 2022-03-04 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1BAH
 | | A TWO DISULFIDE DERIVATIVE OF CHARYBDOTOXIN WITH DISULFIDE 13-33 REPLACED BY TWO ALPHA-AMINOBUTYRIC ACIDS, NMR, 30 STRUCTURES | | 分子名称: | CHARYBDOTOXIN | | 著者 | Song, J, Gilquin, B, Jamin, N, Guenneugues, M, Dauplais, M, Vita, C, Menez, A. | | 登録日 | 1996-06-06 | | 公開日 | 1997-01-11 | | 最終更新日 | 2020-01-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing.
Biochemistry, 36, 1997
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