7NP4
 
 | | cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | | 登録日 | 2021-02-26 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
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7NP3
 | | cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture | | 分子名称: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Giese, H.M, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | | 登録日 | 2021-02-26 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
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6I2Z
 | | Isolated globin domain of the Bordetella pertussis globin-coupled sensor | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Uncharacterized protein | | 著者 | Germani, F, De Schutter, A, Cuypers, B, Berghmans, H, Van Hauwaert, M.-L, Bruno, S, Mozzarelli, A, Moens, L, Van Doorslaer, S, Bolognesi, M, Pesce, A, Dewilde, S. | | 登録日 | 2018-11-02 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural and Functional Characterization of the Globin-Coupled Sensors ofAzotobacter vinelandiiandBordetella pertussis.
Antioxid.Redox Signal., 32, 2020
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8QJE
 | | Neck of phage 812 virion (C12) | | 分子名称: | Portal protein, Putative neck protein, ZINC ION | | 著者 | Cienikova, Z, Novacek, J, Fuzik, T, Benesik, M, Plevka, P. | | 登録日 | 2023-09-13 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | | 主引用文献 | Genome anchoring, retention, and release by neck proteins of Herelleviridae phage 812
To Be Published
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8QKH
 | | Neck of phage 812 virion (C6) | | 分子名称: | Baseplate hub assembly protein, Capsid protein, Non-cytoplasmic protein, ... | | 著者 | Cienikova, Z, Novacek, J, Fuzik, T, Benesik, M, Plevka, P. | | 登録日 | 2023-09-15 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Genome anchoring, retention, and release by neck proteins of Herelleviridae phage 812
To Be Published
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8R7H
 | | Cryo-EM structure of Human SHMT1 | | 分子名称: | Serine hydroxymethyltransferase, cytosolic | | 著者 | Spizzichino, S, Marabelli, C, Bharadwaj, A, Jakobi, A.J, Chaves-Sanjuan, A, Giardina, G, Bolognesi, M, Cutruzzola, F. | | 登録日 | 2023-11-24 | | 公開日 | 2024-07-24 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1.
Mol.Cell, 84, 2024
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3NA4
 | | D53P beta-2 microglobulin mutant | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin | | 著者 | Azinas, S, Ricagno, S, Bolognesi, M. | | 登録日 | 2010-06-01 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | D-strand perturbation and amyloid propensity in beta-2 microglobulin
Febs J., 278, 2011
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4FXL
 | | Crystal structure of the D76N Beta-2 Microglobulin mutant | | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M. | | 登録日 | 2012-07-03 | | 公開日 | 2012-08-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin.
N.Engl.J.Med., 366, 2012
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4EC4
 | | XIAP-BIR3 in complex with a potent divalent Smac mimetic | | 分子名称: | (3S,6S,7S,9aS,3'S,6'S,7'S,9a'S)-N,N'-(benzene-1,4-diylbis{butane-4,1-diyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethanediyl]})bis[7-(hydroxymethyl)-6-{[(2S)-2-(methylamino)butanoyl]amino}-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide], 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Baculoviral IAP repeat-containing protein 4, ... | | 著者 | Mastrangelo, E, Cossu, F, Bolognesi, M, Milani, M. | | 登録日 | 2012-03-26 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
Plos One, 7, 2012
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1XSO
 | | THREE-DIMENSIONAL STRUCTURE OF XENOPUS LAEVIS CU,ZN SUPEROXIDE DISMUTASE B DETERMINED BY X-RAY CRYSTALLOGRAPHY AT 1.5 ANGSTROMS RESOLUTION | | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Djinovic Carugo, K, Coda, A, Battistoni, A, Carri, M.T, Polticelli, F, Desideri, A, Rotilio, G, Wilson, K.S, Bolognesi, M. | | 登録日 | 1995-03-14 | | 公開日 | 1995-07-10 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
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2NSY
 | | CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS IN COMPLEX WITH NAD-ADENYLATE | | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Rizzi, M, Bolognesi, M, Coda, A. | | 登録日 | 1998-07-14 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure.
Structure, 6, 1998
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4EB9
 | | cIAP1-BIR3 in complex with a divalent Smac mimetic | | 分子名称: | (3S,6S,7S,9aS,3'S,6'S,7'S,9a'S)-N,N'-(benzene-1,4-diylbis{butane-4,1-diyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethanediyl]})bis[7-(hydroxymethyl)-6-{[(2S)-2-(methylamino)butanoyl]amino}-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide], Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Cossu, F, Mastrangelo, E, Bolognesi, M, Milani, M. | | 登録日 | 2012-03-23 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
Plos One, 7, 2012
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1Y9O
 | | 1H NMR Structure of Acylphosphatase from the hyperthermophile Sulfolobus Solfataricus | | 分子名称: | Acylphosphatase | | 著者 | Corazza, A, Rosano, C, Pagano, K, Alverdi, V, Esposito, G, Capanni, C, Bemporad, F, Plakoutsi, G, Stefani, M, Chiti, F, Zuccotti, S, Bolognesi, M, Viglino, P. | | 登録日 | 2004-12-16 | | 公開日 | 2005-11-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus
Proteins, 62, 2006
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2OXT
 | | Crystal structure of Meaban virus nucleoside-2'-O-methyltransferase | | 分子名称: | NUCLEOSIDE-2'-O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE | | 著者 | Mastrangelo, E, Milani, M, Bollati, M, Bolognesi, M. | | 登録日 | 2007-02-21 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase
Protein Sci., 16, 2007
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5GDS
 | | HIRUNORMS ARE TRUE HIRUDIN MIMETICS. THE CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN:HIRUNORM V COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN, HIRUNORM V | | 著者 | De Simone, G, Lombardi, A, Galdiero, S, Nastri, F, Della Morte, R, Staiano, N, Pedone, C, Bolognesi, M, Pavone, V. | | 登録日 | 1997-07-17 | | 公開日 | 1998-01-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.
Protein Sci., 7, 1998
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2C0K
 | | The structure of hemoglobin from the botfly Gasterophilus intestinalis | | 分子名称: | HEMOGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Pesce, A, Nardini, M, Dewilde, S, Hoogewijs, D, Ascenzi, P, Moens, L, Bolognesi, M. | | 登録日 | 2005-09-05 | | 公開日 | 2005-11-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Modulation of Oxygen Binding to Insect Hemoglobins: The Structure of Hemoglobin from the Botfly Gasterophilus Intestinalis.
Protein Sci., 14, 2005
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1VHB
 | | BACTERIAL DIMERIC HEMOGLOBIN FROM VITREOSCILLA STERCORARIA | | 分子名称: | HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Tarricone, C, Galizzi, A, Coda, A, Ascenzi, P, Bolognesi, M. | | 登録日 | 1997-02-19 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Unusual structure of the oxygen-binding site in the dimeric bacterial hemoglobin from Vitreoscilla sp.
Structure, 5, 1997
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3QZZ
 | | 3D Structure of Ferric Methanosarcina Acetivorans Protoglobin Y61W mutant in Aquomet form | | 分子名称: | Methanosarcina acetivorans protoglobin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Pesce, A, Tilleman, L, Dewilde, S, Ascenzi, P, Coletta, M, Ciaccio, C, Bruno, S, Moens, L, Bolognesi, M, Nardini, M. | | 登録日 | 2011-03-07 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants.
Iubmb Life, 63, 2011
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2BJD
 | | Sulfolobus Solfataricus Acylphosphatase. Triclinic space group | | 分子名称: | ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Rosano, C, Zuccotti, S, Bolognesi, M. | | 登録日 | 2005-02-02 | | 公開日 | 2005-11-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
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2CAM
 | | AVIDIN MUTANT (K3E,K9E,R26D,R124L) | | 分子名称: | AVIDIN | | 著者 | Rosano, C, Arosio, P, Bolognesi, M. | | 登録日 | 1998-03-27 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli.
Eur.J.Biochem., 256, 1998
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5FAF
 | | N184K pathological variant of gelsolin domain 2 (orthorhombic form) | | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Boni, F, Milani, M, Ricagno, s, Bolognesi, M, de Rosa, M. | | 登録日 | 2015-12-11 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
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4L3C
 | | Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | 著者 | Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. | | 登録日 | 2013-06-05 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
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2OK7
 | | Ferredoxin-NADP+ reductase from Plasmodium falciparum with 2'P-AMP | | 分子名称: | ADENOSINE-2'-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Putative ferredoxin--NADP reductase, ... | | 著者 | Milani, M, Mastrangelo, E, Bolognesi, M. | | 登録日 | 2007-01-16 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis.
J.Mol.Biol., 367, 2007
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2OK8
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1YIO
 | | Crystallographic structure of response regulator StyR from Pseudomonas fluorescens | | 分子名称: | MAGNESIUM ION, MERCURY (II) ION, response regulatory protein | | 著者 | Milani, M, Leoni, L, Rampioni, G, Zennaro, E, Ascenzi, P, Bolognesi, M. | | 登録日 | 2005-01-12 | | 公開日 | 2005-09-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Active-like Structure in the Unphosphorylated StyR Response Regulator Suggests a Phosphorylation- Dependent Allosteric Activation Mechanism
STRUCTURE, 13, 2005
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