8CZK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8czk by Molmil](/molmil-images/mine/8czk) | |
8D19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d19 by Molmil](/molmil-images/mine/8d19) | Human LanCL1 bound to GSH | Descriptor: | GLUTATHIONE, Glutathione S-transferase LANCL1, ZINC ION | Authors: | Ongpipattanakul, C, Nair, S.K. | Deposit date: | 2022-05-26 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | The mechanism of thia-Michael addition catalyzed by LanC enzymes. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8D0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8d0v by Molmil](/molmil-images/mine/8d0v) | Human LanCL1 C264A mutant bound to GSH | Descriptor: | GLUTATHIONE, Glutathione S-transferase LANCL1, ZINC ION | Authors: | Ongpipattanakul, C, Nair, S.K. | Deposit date: | 2022-05-26 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The mechanism of thia-Michael addition catalyzed by LanC enzymes. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8F5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f5m by Molmil](/molmil-images/mine/8f5m) | Crystal structure of P74 gp62 | Descriptor: | Envelope glycoprotein gp62, MAGNESIUM ION | Authors: | Bae, B, Nair, S.K. | Deposit date: | 2022-11-14 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail. Nat Commun, 15, 2024
|
|
4YAR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yar by Molmil](/molmil-images/mine/4yar) | 2-Hydroxyethylphosphonate dioxygenase (HEPD) E176H | Descriptor: | 2-hydroxyethylphosphonate dioxygenase, ACETATE ION, CADMIUM ION, ... | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2015-02-17 | Release date: | 2015-03-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase. J.Am.Chem.Soc., 137, 2015
|
|
8FTS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fts by Molmil](/molmil-images/mine/8fts) | SgvM methyltransferase with SAH and alpha-ketoleucine | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Kuzelka, K, Nair, S.K. | Deposit date: | 2023-01-13 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases Nat Commun, 14, 2023
|
|
8FTV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ftv by Molmil](/molmil-images/mine/8ftv) | |
1V1O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v1o by Molmil](/molmil-images/mine/1v1o) | |
6M78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m78 by Molmil](/molmil-images/mine/6m78) | Aromatic interactions drive the coupled folding and binding of the intrinsically disordered Sesbania mosaic virus VPg protein | Descriptor: | Polyprotein | Authors: | Dixit, K, Karanth, N.M, Nair, S, Kumari, K, Chakraborti, K.S, Savithri, H.S, Sarma, S.P. | Deposit date: | 2020-03-17 | Release date: | 2021-01-27 | Method: | SOLUTION NMR | Cite: | Aromatic Interactions Drive the Coupled Folding and Binding of the Intrinsically Disordered Sesbania mosaic Virus VPg Protein. Biochemistry, 59, 2020
|
|
6LXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lxf by Molmil](/molmil-images/mine/6lxf) | Aromatic interactions drive the coupled folding and binding of the intrinsically disordered Sesbania mosaic virus VPg protein. | Descriptor: | Polyprotein | Authors: | Dixit, K, Karanth, N.M, Nair, S, Kumari, K, Chakrabarti, K.S, Savithri, H.S, Sarma, S.P. | Deposit date: | 2020-02-11 | Release date: | 2021-01-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Aromatic Interactions Drive the Coupled Folding and Binding of the Intrinsically Disordered Sesbania mosaic Virus VPg Protein. Biochemistry, 59, 2020
|
|
8FTR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ftr by Molmil](/molmil-images/mine/8ftr) | SgvM methyltransferase with MTA and alpha-ketoleucine | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methyltransferase, ... | Authors: | Kuzelka, K, Nair, S.K. | Deposit date: | 2023-01-13 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases. Nat Commun, 14, 2023
|
|
8UZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uzd by Molmil](/molmil-images/mine/8uzd) | |
8CWX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cwx by Molmil](/molmil-images/mine/8cwx) | |
6MPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mpz by Molmil](/molmil-images/mine/6mpz) | Crystal structure of a double glycine motif protease from AMS/PCAT transporter in complex with the leader peptide | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE, Double Glycine Motif Protease domain from AMS/PCAT Transporter, peptide aldehyde inhibitor 1 based on the ProcA2.8 leader peptide | Authors: | Dong, S.-H, Nair, S.K. | Deposit date: | 2018-10-09 | Release date: | 2019-02-06 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease. Elife, 8, 2019
|
|
6E6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e6y by Molmil](/molmil-images/mine/6e6y) | Dieckmann cyclase, NcmC | Descriptor: | Dieckmann cyclase, NcmC, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chem.Biol., 2020
|
|
6E6T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e6t by Molmil](/molmil-images/mine/6e6t) | Dieckmann cyclase, NcmC, bound to cerulenin | Descriptor: | (4S,5R)-4,5-dihydroxy-5-[(3E,6E)-octa-3,6-dien-1-yl]pyrrolidin-2-one, NcmC, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chem.Biol., 2020
|
|
6E6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e6u by Molmil](/molmil-images/mine/6e6u) | Variant C89S of Dieckmann cyclase, NcmC | Descriptor: | Dieckmann cyclase, NcmC, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chem.Biol., 2020
|
|
6EC7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ec7 by Molmil](/molmil-images/mine/6ec7) | |
6EC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ec8 by Molmil](/molmil-images/mine/6ec8) | |
5F2O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5f2o by Molmil](/molmil-images/mine/5f2o) | |
8T19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t19 by Molmil](/molmil-images/mine/8t19) | RiPP precursor peptide recognition element (RRE) domain of Ocin-ThiF-like partner protein, PbtF, bound to an 8 residue fragment of its precursor peptide, PbtA | Descriptor: | MAGNESIUM ION, PbtA, PbtF | Authors: | Cogan, D.P, Nair, S.K, Mitchell, D.A. | Deposit date: | 2023-06-02 | Release date: | 2024-06-12 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Discovery and validation of RRE domains To Be Published
|
|
5F2N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5f2n by Molmil](/molmil-images/mine/5f2n) | |
6MJF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mjf by Molmil](/molmil-images/mine/6mjf) | Catalytic Domain of dbOphMA | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, dbOphM | Authors: | Ongpipatanakul, C, Nair, S.K. | Deposit date: | 2018-09-20 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.198 Å) | Cite: | Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis. ACS Chem. Biol., 13, 2018
|
|
6MJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mjg by Molmil](/molmil-images/mine/6mjg) | |
6NMX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nmx by Molmil](/molmil-images/mine/6nmx) | Threonine synthase from Bacillus subtilis ATCC 6633 with PLP and APPA | Descriptor: | (2E,3Z)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}-5-phosphonopent-3-enoic acid, Threonine synthase | Authors: | Petronikolou, N, Nair, S.K. | Deposit date: | 2019-01-12 | Release date: | 2019-03-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.971 Å) | Cite: | Molecular Basis of Bacillus subtilis ATCC 6633 Self-Resistance to the Phosphono-oligopeptide Antibiotic Rhizocticin. ACS Chem. Biol., 14, 2019
|
|