2ZEW
 
 | | Family 16 Cabohydrate Binding Domain Module 1 | | Descriptor: | CALCIUM ION, S-layer associated multidomain endoglucanase | | Authors: | Bae, B, Nair, S.K. | | Deposit date: | 2007-12-18 | | Release date: | 2008-03-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Molecular Basis for the Selectivity and Specificity of Ligand Recognition by the Family 16 Carbohydrate-binding Modules from Thermoanaerobacterium polysaccharolyticum ManA
J.Biol.Chem., 283, 2008
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4ZOQ
 | | Crystal Structure of a Lanthipeptide Protease | | Descriptor: | Intracellular serine protease | | Authors: | Dong, S.H, Nair, S.K. | | Deposit date: | 2015-05-06 | | Release date: | 2016-03-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage.
Chem Sci, 6, 2015
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8F5M
 | | Crystal structure of P74 gp62 | | Descriptor: | Envelope glycoprotein gp62, MAGNESIUM ION | | Authors: | Bae, B, Nair, S.K. | | Deposit date: | 2022-11-14 | | Release date: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail.
Nat Commun, 15, 2024
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4YAR
 | | 2-Hydroxyethylphosphonate dioxygenase (HEPD) E176H | | Descriptor: | 2-hydroxyethylphosphonate dioxygenase, ACETATE ION, CADMIUM ION, ... | | Authors: | Chekan, J.R, Nair, S.K. | | Deposit date: | 2015-02-17 | | Release date: | 2015-03-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase.
J.Am.Chem.Soc., 137, 2015
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8T19
 | | RiPP precursor peptide recognition element (RRE) domain of Ocin-ThiF-like partner protein, PbtF, bound to an 8 residue fragment of its precursor peptide, PbtA | | Descriptor: | MAGNESIUM ION, PbtA, PbtF | | Authors: | Cogan, D.P, Nair, S.K, Mitchell, D.A. | | Deposit date: | 2023-06-02 | | Release date: | 2024-06-12 | | Method: | X-RAY DIFFRACTION (1.23 Å) | | Cite: | Discovery and validation of RRE domains
To Be Published
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6WPA
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8FTS
 | | SgvM methyltransferase with SAH and alpha-ketoleucine | | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Kuzelka, K, Nair, S.K. | | Deposit date: | 2023-01-13 | | Release date: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases
Nat Commun, 14, 2023
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8FTV
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8FTR
 | | SgvM methyltransferase with MTA and alpha-ketoleucine | | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methyltransferase, ... | | Authors: | Kuzelka, K, Nair, S.K. | | Deposit date: | 2023-01-13 | | Release date: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases.
Nat Commun, 14, 2023
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4E5N
 | | Thermostable phosphite dehydrogenase in complex with NAD | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Thermostable phosphite dehydrogenase | | Authors: | Zou, Y, Zhang, H, Nair, S.K. | | Deposit date: | 2012-03-14 | | Release date: | 2012-05-30 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
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6WP7
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4E5P
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4E5K
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4E5M
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1V1O
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4EBF
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2I8U
 | | GDP-mannose mannosyl hydrolase-calcium-GDP product complex | | Descriptor: | CALCIUM ION, GDP-mannose mannosyl hydrolase, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Zou, Y, Li, C, Brunzelle, J.S, Nair, S.K. | | Deposit date: | 2006-09-03 | | Release date: | 2007-06-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme
Biochemistry, 46, 2007
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2I8T
 | | GDP-mannose mannosyl hydrolase-calcium-GDP-mannose complex | | Descriptor: | CALCIUM ION, GDP-mannose mannosyl hydrolase, GLYCEROL, ... | | Authors: | Zou, Y, Li, C, Brunzelle, J.S, Nair, S.K. | | Deposit date: | 2006-09-03 | | Release date: | 2007-06-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme
Biochemistry, 46, 2007
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1OKM
 | | CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE | | Descriptor: | 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | | Authors: | Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. | | Deposit date: | 1996-06-25 | | Release date: | 1997-01-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor.
J.Am.Chem.Soc., 118, 1996
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5F2O
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5F2N
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4KV1
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8F72
 | | Phage P32 gp64- RNA polymerase | | Descriptor: | MAGNESIUM ION, TPR_REGION domain-containing protein | | Authors: | Bae, B, Nair, S.K. | | Deposit date: | 2022-11-17 | | Release date: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Thermophage RNA polymerase
To Be Published
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4KV4
 | | Brd4 Bromodomain 2 in Complex with Acetylated Rel Peptide | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Bromodomain-containing protein 4, Rel Peptide | | Authors: | Zhang, H, Nair, S.K. | | Deposit date: | 2013-05-22 | | Release date: | 2013-06-26 | | Last modified: | 2014-05-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Brd4 maintains constitutively active NF-kappa B in cancer cells by binding to acetylated RelA.
Oncogene, 33, 2014
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5DM0
 | | Crystal structure of the plantazolicin methyltransferase BamL in complex with triazolic desmethylPZN analog and SAH | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ethyl 2-(2-{2-[(1S)-1-amino-4-carbamimidamidobutyl]-1,3-thiazol-4-yl}-5-methyl-1,3-oxazol-4-yl)-1,3-thiazole-4-carboxylate, ... | | Authors: | Hao, Y, Nair, S.K. | | Deposit date: | 2015-09-07 | | Release date: | 2015-09-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin.
Acs Chem.Biol., 10, 2015
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