1GYT
 
 | | E. coli Aminopeptidase A (PepA) | | 分子名称: | CARBONATE ION, CHLORIDE ION, CYTOSOL AMINOPEPTIDASE, ... | | 著者 | Straeter, N. | | 登録日 | 2002-04-29 | | 公開日 | 2002-06-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-Ray Structure of Aminopeptidase a from Escherichia Coli and a Model for the Nucleoprotein Complex in Xer Site-Specific Recombination
Embo J., 18, 1999
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3ZUI
 | | OMCI in complex with palmitoleic acid | | 分子名称: | COMPLEMENT INHIBITOR, PALMITOLEIC ACID | | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | | 登録日 | 2011-07-19 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury.
J.Biol.Chem., 288, 2013
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3ZUO
 | | OMCI in complex with leukotriene B4 | | 分子名称: | COMPLEMENT INHIBITOR, LEUKOTRIENE B4 | | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | | 登録日 | 2011-07-19 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury.
J.Biol.Chem., 288, 2013
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3ZWK
 | | The 3-dimensional structure of MpgP from Thermus thermophilus HB27, in complex with the metavanadate | | 分子名称: | MAGNESIUM ION, MANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE, VANADATE ION | | 著者 | Goncalves, S, Esteves, A.M, Santos, H, Borges, N, Matias, P.M. | | 登録日 | 2011-08-01 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | The Three-Dimensional Structure of Mannosyl-3-Phosphoglycerate Phosphatase from Thermus Thermophilus Hb27: A New Member of the Haloalkanoic Acid Dehalogenase Superfamily.
Biochemistry, 50, 2011
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1HSX
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1HU3
 | | MIDDLE DOMAIN OF HUMAN EIF4GII | | 分子名称: | EIF4GII | | 著者 | Marcotrigiano, J, Lomakin, I, Pestova, T.V, Hellen, C.U.T, Sonenberg, N, Burley, S.K. | | 登録日 | 2001-01-03 | | 公開日 | 2001-02-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery.
Mol.Cell, 7, 2001
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1HQC
 | | STRUCTURE OF RUVB FROM THERMUS THERMOPHILUS HB8 | | 分子名称: | ADENINE, MAGNESIUM ION, RUVB | | 著者 | Yamada, K, Kunishima, N, Mayanagi, K, Iwasaki, H, Morikawa, K. | | 登録日 | 2000-12-15 | | 公開日 | 2001-02-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of the Holliday junction migration motor protein RuvB from Thermus thermophilus HB8.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1HUV
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3ZX2
 | | NTPDase1 in complex with Decavanadate | | 分子名称: | ACETIC ACID, CHLORIDE ION, DECAVANADATE, ... | | 著者 | Zebisch, M, Schaefer, P, Straeter, N. | | 登録日 | 2011-08-04 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystallographic Evidence for a Domain Motion in Rat Nucleoside Triphosphate Diphosphohydrolase (Ntpdase) 1.
J.Mol.Biol., 415, 2012
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2Q2V
 | | Structure of D-3-Hydroxybutyrate Dehydrogenase from Pseudomonas putida | | 分子名称: | Beta-D-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Paithankar, K.S, Feller, C, Kuettner, E.B, Keim, A, Grunow, M, Strater, N. | | 登録日 | 2007-05-29 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.
Febs J., 274, 2007
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2PQ2
 | | Structure of serine proteinase K complex with a highly flexible hydrophobic peptide at 1.8A resolution | | 分子名称: | CALCIUM ION, GALAG peptide, NITRATE ION, ... | | 著者 | Ethayathulla, A.S, Singh, A.K, Singh, N, Sharma, S, Sinha, M, Somvanshi, R.K, Kaur, P, Dey, S, Srinivasan, A, Singh, T.P. | | 登録日 | 2007-05-01 | | 公開日 | 2007-05-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure of serine proteinase K complex with a highly flexible hydrophobic peptide at 1.8A resolution
To be Published
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9CUO
 | | Crystal structure of CRBN with compound 3 | | 分子名称: | (3S)-3-(3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidine-2,6-dione, 1,2-ETHANEDIOL, Protein cereblon, ... | | 著者 | Zheng, X, Ji, N, Campbell, V, Slavin, A, Zhu, X, Chen, D, Rong, H, Enerson, B, Mayo, M, Sharma, K, Browne, C.M, Klaus, C.R, Li, H, Massa, G, McDonald, A.A, Shi, Y, Sintchak, M, Skouras, S, Walther, D.M, Yuan, K, Zhang, Y, Kelleher, J, Guang, L, Luo, X, Mainolfi, N, Weiss, M.M. | | 登録日 | 2024-07-26 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases.
J.Med.Chem., 2024
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2PLR
 | | Crystal structure of dTMP kinase (st1543) from Sulfolobus Tokodaii Strain7 | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Kanaujia, S.P, Jeyakanthan, J, Rafi, Z.A, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-20 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of dTMP kinase (st1543) from Sulfolobus Tokodaii Strain7
To be Published
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2PYZ
 | | Crystal structure of the complex of proteinase K with auramine at 1.8A resolution | | 分子名称: | 4,4'-(AMINOMETHYLENE)BIS(N,N-DIMETHYLANILINE), CALCIUM ION, NITRATE ION, ... | | 著者 | Singh, A.K, Singh, N, Sinha, M, Sharma, S, Bhushan, A, Kaur, P, Singh, T.P. | | 登録日 | 2007-05-17 | | 公開日 | 2007-07-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Crystal structure of the complex of Proteinase K with auramine at 1.8A resolution
To be Published
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4LUD
 | | Crystal Structure of HCK in complex with the fluorescent compound SKF86002 | | 分子名称: | 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. | | 登録日 | 2013-07-25 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
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2Q1P
 | | Crystal Structure of Phospholipase A2 complex with propanol at 1.5 A resolution | | 分子名称: | N-PROPANOL, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | 著者 | Kumar, S, Hariprasad, G, Singh, N, Sharma, S, Kaur, P, Perbandt, M, Betzel, C, Singh, T.P. | | 登録日 | 2007-05-25 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Phospholipase A2 complex with propanol at 1.5 A resolution
To be Published
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1QSI
 | | MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME | | 分子名称: | CARBON MONOXIDE, PROTEIN (HEMOGLOBIN ALPHA CHAIN), PROTEIN (HEMOGLOBIN BETA CHAIN), ... | | 著者 | Miyazaki, G, Morimoto, H, Yun, K.-M, Park, S.-Y, Nakagawa, A, Minagawa, H, Shibayama, N. | | 登録日 | 1999-06-22 | | 公開日 | 1999-07-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Magnesium(II) and zinc(II)-protoporphyrin IX's stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme.
J.Mol.Biol., 292, 1999
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2PPI
 | | Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin | | 分子名称: | Gigaxonin | | 著者 | Amos, A, Turnbull, A.P, Tickle, J, Keates, T, Bullock, A, Savitsky, P, Burgess-Brown, N, Debreczeni, J.E, Ugochukwu, E, Umeano, C, Pike, A.C.W, Papagrigoriou, E, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-30 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin.
To be Published
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2PSM
 | | Crystal structure of Interleukin 15 in complex with Interleukin 15 receptor alpha | | 分子名称: | BENZAMIDINE, Interleukin-15, Interleukin-15 receptor alpha chain | | 著者 | Olsen, S.K, Murayama, K, Kishishita, S, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Ota, N, Kanagawa, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-05-07 | | 公開日 | 2007-11-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal Structure of the Interleukin-15{middle dot}Interleukin-15 Receptor {alpha} Complex: INSIGHTS INTO TRANS AND CIS PRESENTATION
J.Biol.Chem., 282, 2007
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1QQ2
 | | CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23. | | 分子名称: | CHLORIDE ION, THIOREDOXIN PEROXIDASE 2 | | 著者 | Hirotsu, S, Abe, Y, Okada, K, Nagahara, N, Hori, H, Nishino, T, Hakoshima, T. | | 登録日 | 1999-06-10 | | 公開日 | 1999-10-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product.
Proc.Natl.Acad.Sci.USA, 96, 1999
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8Y7Z
 | | Cryo-EM structure of the monomeric SPARSA gRNA-ssDNA complex | | 分子名称: | DNA (25-mer), MAGNESIUM ION, Piwi domain protein, ... | | 著者 | Zhang, J.T, Cui, N, Wei, X.Y, Jia, N. | | 登録日 | 2024-02-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Tetramerization-dependent activation of the Sir2-associated short prokaryotic Argonaute immune system.
Nat Commun, 15, 2024
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8Y82
 | | Cryo-EM structure of the tetrameric SPARSA gRNA-ssDNA-NAD+ complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, DNA (25-mer), MAGNESIUM ION, ... | | 著者 | Zhang, J.T, Cui, N, Wei, X.Y, Jia, N. | | 登録日 | 2024-02-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Tetramerization-dependent activation of the Sir2-associated short prokaryotic Argonaute immune system.
Nat Commun, 15, 2024
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8Y80
 | | Cryo-EM structure of the tetrameric SPARSA gRNA-ssDNA complex | | 分子名称: | DNA (25-mer), MAGNESIUM ION, Piwi domain protein, ... | | 著者 | Zhang, J.T, Cui, N, Wei, X.Y, Jia, N. | | 登録日 | 2024-02-05 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Tetramerization-dependent activation of the Sir2-associated short prokaryotic Argonaute immune system.
Nat Commun, 15, 2024
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2Q2Q
 | | Structure of D-3-Hydroxybutyrate Dehydrogenase from Pseudomonas putida | | 分子名称: | Beta-D-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Paithankar, K.S, Feller, C, Kuettner, E.B, Keim, A, Grunow, M, Strater, N. | | 登録日 | 2007-05-29 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.
Febs J., 274, 2007
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4LVA
 | | Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | | 分子名称: | 1,2-ETHANEDIOL, N-(4-{[4-(pyrrolidin-1-yl)piperidin-1-yl]sulfonyl}benzyl)-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine 1,1-dioxide, Nicotinamide phosphoribosyltransferase, ... | | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | | 登録日 | 2013-07-26 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
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