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PDB: 63 件

3N06
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A mutant human Prolactin receptor antagonist H27A in complex with the extracellular domain of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-05-13
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3N0P
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A mutant human Prolactin receptor antagonist H30A in complex with the extracellular domain of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-05-14
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCB
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A mutant human Prolactin receptor antagonist H180A in complex with the extracellular domain of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCF
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A mutant human Prolactin receptor antagonist H30A in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
1QW1
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Solution Structure of the C-Terminal Domain of DtxR residues 110-226
分子名称: Diphtheria toxin repressor
著者Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Love, J.F, Murphy, J.R, Logan, T.M.
登録日2003-08-29
公開日2005-03-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch.
Biochemistry, 44, 2005
1QVP
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C terminal SH3-like domain from Diphtheria toxin Repressor residues 144-226.
分子名称: Diphtheria toxin repressor
著者Wylie, G.P, Rangachari, V, Bienkiewicz, E.A, Marin, V, Bhattacharya, N, Love, J.F, Murphy, J.R, Logan, T.M.
登録日2003-08-28
公開日2004-11-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch.
Biochemistry, 44, 2005
2L3O
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Solution structure of murine interleukin 3
分子名称: Interleukin 3
著者Yao, S, Young, I.G, Norton, R.S, Murphy, J.M.
登録日2010-09-20
公開日2011-08-10
実験手法SOLUTION NMR
主引用文献Murine interleukin-3: structure, dynamics, and conformational heterogeneity in solution.
Biochemistry, 50, 2011
3NCC
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A human Prolactin receptor antagonist in complex with the mutant extracellular domain H188A of the human prolactin receptor
分子名称: CARBONATE ION, CHLORIDE ION, Prolactin, ...
著者Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E.
登録日2010-06-04
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
4MWI
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Crystal structure of the human MLKL pseudokinase domain
分子名称: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, GLYCEROL, Mixed lineage kinase domain-like protein
著者Czabotar, P.E, Murphy, J.M.
登録日2013-09-25
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL.
Biochem.J., 457, 2014
4QQV
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Extracellular domains of mouse IL-3 beta receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-3 receptor class 2 subunit beta
著者Jackson, C.J, Young, I.G, Murphy, J.M, Carr, P.D, Ewens, C.L, Dai, J, Ollis, D.L.
登録日2014-06-30
公開日2014-09-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Crystal structure of the mouse interleukin-3 beta-receptor: insights into interleukin-3 binding and receptor activation.
Biochem.J., 463, 2014
4GL9
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BU of 4gl9 by Molmil
Crystal structure of inhibitory protein SOCS3 in complex with JAK2 kinase domain and fragment of GP130 intracellular domain
分子名称: 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Interleukin-6 receptor subunit beta, PHOSPHATE ION, ...
著者Kershaw, N.J, Murphy, J.M, Laktyushin, A, Nicola, N.A, Babon, J.J.
登録日2012-08-14
公開日2013-03-06
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
Nat.Struct.Mol.Biol., 20, 2013
4FQN
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Crystal structure of the CCM2 C-terminal Harmonin Homology Domain (HHD)
分子名称: Malcavernin
著者Fisher, O.S, Zhang, R, Li, X, Murphy, J.W, Boggon, T.J.
登録日2012-06-25
公開日2012-12-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus.
Febs Lett., 587, 2013
1BYM
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BU of 1bym by Molmil
SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OF DIPHTHERIA TOXIN REPRESSOR
分子名称: PROTEIN (DIPHTHERIA TOXIN REPRESSOR)
著者Wang, G, Wylie, G.P, Twigg, P.D, Caspar, D.L.D, Murphy, J.R, Logan, T.M.
登録日1998-10-17
公開日1998-10-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein.
Proc.Natl.Acad.Sci.USA, 96, 1999
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