5FG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fg5 by Molmil](/molmil-images/mine/5fg5) | Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe | Descriptor: | NITRATE ION, Peregrin, ~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide | Authors: | Tallant, C, Owen, D.R, Gerstenberger, B.S, Savitsky, P, Chaikuad, A, Fedorov, O, Nunez-Alonso, G, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Brennan, P.E, Knapp, S. | Deposit date: | 2015-12-20 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe To Be Published
|
|
5FBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fbx by Molmil](/molmil-images/mine/5fbx) | Crystal structure of the first bromodomain of human BRD4 in complex with PNZ5 isoxazole inhibitor | Descriptor: | (3~{S})-5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methyl-3-phenyl-3~{H}-isoindol-1-one, Bromodomain-containing protein 4 | Authors: | Tallant, C, Clark, P.G.K, Siejka, P, Fedorov, O, Nowak, R, Srikannathasan, V, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Brennan, P.E, Dixon, D, Knapp, S. | Deposit date: | 2015-12-14 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the first bromodomain of human BRD4 in complex with PNZ5 isoxazole inhibitor To Be Published
|
|
5DKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dkc by Molmil](/molmil-images/mine/5dkc) | Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with PFI-3 chemical probe | Descriptor: | (2E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]hept-2-yl]prop-2-en-1-one, Probable global transcription activator SNF2L2, ZINC ION | Authors: | Tallant, C, Owen, D.R, Gerstenberger, B.S, Fedorov, O, Savitsky, P, Nunez-Alonso, G, Fonseca, M, Krojer, T, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Knapp, S. | Deposit date: | 2015-09-03 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with PFI-3 chemical probe To Be Published
|
|
2C07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c07 by Molmil](/molmil-images/mine/2c07) | Oxoacyl-ACP reductase of Plasmodium falciparum | Descriptor: | 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE, SULFATE ION | Authors: | Urch, J.E, Wickramasinghe, S.R, Inglis, K.A, Muller, S, Fairlamb, A.H, van Aalten, D.M.F. | Deposit date: | 2005-08-26 | Release date: | 2005-10-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kinetic, Inhibition and Structural Studies on 3-Oxoacyl-Acp Reductase from Plasmodium Falciparum, a Key Enzyme in Fatty Acid Biosynthesis. Biochem.J., 393, 2006
|
|
2C0D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c0d by Molmil](/molmil-images/mine/2c0d) | Structure of the mitochondrial 2-cys peroxiredoxin from Plasmodium falciparum | Descriptor: | THIOREDOXIN PEROXIDASE 2 | Authors: | Boucher, I.W, Brannigan, J.A, Wilkinson, A.J, Brzozowski, A.M, Muller, S. | Deposit date: | 2005-09-01 | Release date: | 2006-11-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural and Biochemical Characterisation of a Mitochondrial Peroxiredoxin from Plasmodium Falciparum Mol.Microbiol., 61, 2006
|
|
1CVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cvq by Molmil](/molmil-images/mine/1cvq) | SOLUTION STRUCTURE OF THE ANALOGUE RETRO-INVERSO MGREGRIGGC IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 7 STRUCTURES | Descriptor: | HISTONE H3 | Authors: | Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, M.T. | Deposit date: | 1999-08-24 | Release date: | 1999-09-02 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
|
|
1BFW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bfw by Molmil](/molmil-images/mine/1bfw) | RETRO-INVERSO ANALOGUE OF THE G-H LOOP OF VP1 IN FOOT-AND-MOUTH-DISEASE (FMD) VIRUS, NMR, 10 STRUCTURES | Descriptor: | VP1 PROTEIN | Authors: | Petit, M.C, Benkirane, N, Guichard, G, Phan Chan Du, A, Cung, M.T, Briand, J.P, Muller, S. | Deposit date: | 1998-05-22 | Release date: | 1999-01-13 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of a retro-inverso peptide analogue mimicking the foot-and-mouth disease virus major antigenic site. Structural basis for its antigenic cross-reactivity with the parent peptide. J.Biol.Chem., 274, 1999
|
|
1CS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cs9 by Molmil](/molmil-images/mine/1cs9) | SOLUTION STRUCTURE OF CGGIRGERA IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 7 STRUCTURES | Descriptor: | HISTONE H3 PEPTIDE | Authors: | Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, M.T. | Deposit date: | 1999-08-18 | Release date: | 1999-09-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
|
|
1CW8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cw8 by Molmil](/molmil-images/mine/1cw8) | SOLUTION STRUCTURE OF THE ANALOGUE RETRO-INVERSO (mA-R)REGRIGGC IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 6 STRUCTURES | Descriptor: | HISTONE H3, METHYLMALONIC ACID | Authors: | Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, T. | Deposit date: | 1999-08-26 | Release date: | 1999-09-03 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
|
|
1CT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ct6 by Molmil](/molmil-images/mine/1ct6) | SOLUTION STRUCTURE OF CGGIRGERG IN CONTACT WITH THE MONOCLONAL ANTIBODY MAB 4X11, NMR, 11 STRUCTURES | Descriptor: | HISTONE H3 PEPTIDE | Authors: | Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, M.T. | Deposit date: | 1999-08-19 | Release date: | 1999-09-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
|
|
1CWZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cwz by Molmil](/molmil-images/mine/1cwz) | Solution structure of the analogue retro-inverso (MA-S)REGRIGGC in contact with the monoclonal antibody MAB 4X11, NMR, 7 structures | Descriptor: | HISTONE H3, METHYLMALONIC ACID | Authors: | Phan Chan Du, A, Petit, M.C, Guichard, G, Briand, J.P, Muller, S, Cung, M.T. | Deposit date: | 1999-08-27 | Release date: | 1999-09-03 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach. Biochemistry, 40, 2001
|
|
1BCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bcv by Molmil](/molmil-images/mine/1bcv) | SYNTHETIC PEPTIDE CORRESPONDING TO THE MAJOR IMMUNOGEN SITE OF FMD VIRUS, NMR, 10 STRUCTURES | Descriptor: | PEPTIDE CORRESPONDING TO THE MAJOR IMMUNOGEN SITE OF FMD VIRUS | Authors: | Petit, M.C, Benkirane, N, Guichard, G, Phan Chan Du, A, Cung, M.T, Briand, J.P, Muller, S. | Deposit date: | 1998-05-03 | Release date: | 1998-11-25 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of a retro-inverso peptide analogue mimicking the foot-and-mouth disease virus major antigenic site. Structural basis for its antigenic cross-reactivity with the parent peptide. J.Biol.Chem., 274, 1999
|
|
1J8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j8z by Molmil](/molmil-images/mine/1j8z) | Solution structure of beta3 analogue peptide (HCYS) of HIV gp41 600-612 loop. | Descriptor: | HCYS BETA3-CYS ANALOGUE OF HIV GP41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-05-23 | Release date: | 2003-07-01 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1JAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jaa by Molmil](/molmil-images/mine/1jaa) | Solution structure of lactam analogue (DapE) of HIV gp41 600-612 loop. | Descriptor: | DapE : (Ace)IWG(Dap)SGKLIETTA ANALOGUE OF HIV GP41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-05-30 | Release date: | 2003-07-01 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1JCP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jcp by Molmil](/molmil-images/mine/1jcp) | Solution structure of the lactam analogue EDap of HIV gp41 600-612 loop. | Descriptor: | Edap : ACE-Ile-Trp-Glu-Ser-Gly-Lys-Leu-Ile-Dap-Thr-Thr-Ala ANALOGUE OF HIV GP41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-06-11 | Release date: | 2003-07-01 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1JC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jc8 by Molmil](/molmil-images/mine/1jc8) | Solution structure of lactam analogue (DDap) of gp41 600-612 loop of HIV | Descriptor: | DDap: (ACE)IWGDSGKLI(DNP)TTA ANALOGUE OF HIV GP41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-06-08 | Release date: | 2003-07-01 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1J8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j8n by Molmil](/molmil-images/mine/1j8n) | Solution structure of beta3-analogue peptide corresponding to the gp41 600-612 loop of HIV. | Descriptor: | HIV1 GP41 HSER analogue peptide Ace-Ile-Trp-Gly-Cys-beta3Ser-Gly-Lys-Leu-Ile-Cys-Thr-Thr-Ala | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-05-22 | Release date: | 2003-07-01 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1IM7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1im7 by Molmil](/molmil-images/mine/1im7) | Solution structure of synthetic cyclic peptide mimicking the loop of HIV-1 gp41 glycoprotein envelope | Descriptor: | GP41-PARENT PEPTIDE ACE-ILE-TRP-GLY-CYS-SER-GLY-LYS-LEU-ILE-CYS-THR-THR-ALA | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-05-10 | Release date: | 2002-10-23 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1J9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j9v by Molmil](/molmil-images/mine/1j9v) | Solution structure of a lactam analogue (DabD) of HIV gp41 600-612 loop. | Descriptor: | DabD (Ace)IWG(DAB)SGKLIDTTA ANALOGUE OF HIV GP41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-05-29 | Release date: | 2003-07-01 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1JD8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jd8 by Molmil](/molmil-images/mine/1jd8) | Solution structure of lactam analogue DapD of HIV gp41 600-612 loop | Descriptor: | Transmembrane protein gp41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-06-13 | Release date: | 2003-07-01 | Last modified: | 2018-10-10 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
1JAR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jar by Molmil](/molmil-images/mine/1jar) | Solution structure of lactam analogue (DDab)of HIV gp41 600-612 loop. | Descriptor: | DDab: (ACE)IWGDSGKLI(DAB)TTA ANALOGUE OF HIV GP41 | Authors: | Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S. | Deposit date: | 2001-05-31 | Release date: | 2003-07-01 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323, 2002
|
|
2L5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l5i by Molmil](/molmil-images/mine/2l5i) | structure of the spliceosomal phosphopeptide P140 (non-phosphorylated form) | Descriptor: | U1 small nuclear ribonucleoprotein 70 kDa | Authors: | Quinternet, M, Page, N, Schall, N, Strub, J, Chaloin, O, Decossas, M, Cung, M, van Dorsselaer, A, Briand, J, Muller, S. | Deposit date: | 2010-11-02 | Release date: | 2010-12-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells. Plos One, 4, 2009
|
|
2L5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l5j by Molmil](/molmil-images/mine/2l5j) | structure of the spliceosomal phosphopeptide P140 (phosphorylated form) | Descriptor: | U1 small nuclear ribonucleoprotein 70 kDa | Authors: | Quinternet, M, Page, N, Schall, N, Strub, J, Chaloin, O, Decossas, M, Cung, M, van Dorsselaer, A, Briand, J, Muller, S. | Deposit date: | 2010-11-02 | Release date: | 2010-12-01 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells. Plos One, 4, 2009
|
|
3V0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v0f by Molmil](/molmil-images/mine/3v0f) | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), form II | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-07 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
|
|
3V0I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v0i by Molmil](/molmil-images/mine/3v0i) | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 256-576, E411F | Descriptor: | SULFATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-08 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
|
|