1JC8

Solution structure of lactam analogue (DDap) of gp41 600-612 loop of HIV

Summary for 1JC8

Entry DOI	10.2210/pdb1jc8/pdb
Related	1IM7 1J8N 1J8Z 1J9V 1JAA 1JAR
NMR Information	BMRB: 5139
Descriptor	DDap: (ACE)IWGDSGKLI(DNP)TTA ANALOGUE OF HIV GP41 (1 entity in total)
Functional Keywords	lactam bond, cyclic peptide, hiv gp41, peptidomimetics., viral protein
Cellular location	Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P12488
Total number of polymer chains	1
Total formula weight	1374.56
Authors	Phan Chan Du, A.,Limal, D.,Semetey, V.,Dali, H.,Jolivet, M.,Desgranges, C.,Cung, M.T.,Briand, J.P.,Petit, M.C.,Muller, S. (deposition date: 2001-06-08, release date: 2003-07-01, Last modification date: 2021-10-27)
Primary citation	Du, A.P.,Limal, D.,Semetey, V.,Dali, H.,Jolivet, M.,Desgranges, C.,Cung, M.T.,Briand, J.P.,Petit, M.C.,Muller, S. Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein. J.Mol.Biol., 323:503-521, 2002 Cited by PubMed: 12381305 DOI: 10.1016/S0022-2836(02)00701-5 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation