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PDB: 4 results

5LIT
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BU of 5lit by Molmil
Structure of the DNA duplex d(AAATTT)2 with the potential antiparasitic drug 6XV at 1.25 A resolution
Descriptor: 4-((4,5-dihydro-1H-imidazol-2-yl)amino)-N-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzamide dihydrochloride, DNA (5'-D(*AP*AP*AP*TP*TP*T)-3'), MAGNESIUM ION
Authors:Millan, C.R, Dardonville, C, de Koning, H.P, Saperas, N, Lourdes Campos, J.
Deposit date:2016-07-15
Release date:2017-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Nucleic Acids Res., 45, 2017
6GIM
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BU of 6gim by Molmil
Structure of the DNA duplex d(AAATTT)2 with [N-(3-chloro-4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)-4-((4,5-dihydro-1H-imidazol-2- yl)amino)benzamide] - (drug JNI18)
Descriptor: DNA (5'-D(*AP*AP*AP*TP*TP*T)-3'), MAGNESIUM ION, [4-[(3-chloranyl-4-imidazolidin-2-ylideneazaniumyl-phenyl)carbamoyl]phenyl]-imidazolidin-2-ylidene-azanium
Authors:Millan, C.R, Dardonvile, C, de Koning, H.P, Saperas, N, Campos, J.L.
Deposit date:2018-05-14
Release date:2018-08-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Nucleic Acids Res., 45, 2017
7M69
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BU of 7m69 by Molmil
E1435Q Ycf1 mutant in inward-facing wide conformation
Descriptor: Metal resistance protein YCF1
Authors:Khandelwal, N.K, Millan, C.R, Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-25
Release date:2022-04-06
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation.
Nat Commun, 13, 2022
7M68
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BU of 7m68 by Molmil
E1435Q Ycf1 mutant in inward-facing narrow conformation
Descriptor: Metal resistance protein YCF1
Authors:Khandelwal, N.K, Millan, C.R, Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-25
Release date:2022-04-06
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation.
Nat Commun, 13, 2022

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PDB entries from 2024-07-03

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