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PDB: 15 件

1RGR
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Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability
分子名称: BETA-ALANINE, Presynaptic density protein 95, postsynaptic protein CRIPT peptide
著者Piserchio, A, Salinas, G.D, Li, T, Marshall, J, Spaller, M.R, Mierke, D.F.
登録日2003-11-12
公開日2004-05-18
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide.
Chem.Biol., 11, 2004
7LXC
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BU of 7lxc by Molmil
Structure and Interactions of DED1 of human cFLIP
分子名称: DED1ch
著者Panaitiu, A.E, Basiashvili, T, Mierke, D.F, Pellegrini, M.
登録日2021-03-03
公開日2021-12-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An engineered construct of cFLIP provides insight into DED1 structure and interactions.
Structure, 30, 2022
1HZN
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NMR SOLUTION STRUCTURE OF THE THIRD EXTRACELLULAR LOOP OF THE CHOLECYSTOKININ A RECEPTOR
分子名称: CHOLECYSTOKININ TYPE A RECEPTOR
著者Giragossian, C, Mierke, D.F.
登録日2001-01-25
公開日2001-04-25
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin A receptor.
Biochemistry, 40, 2001
1FOZ
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STRUCTURE OF CYCLIC PEPTIDE INHIBITORS OF MAMMALIAN RIBONUCLEOTIDE REDUCTASE
分子名称: SYNTHETIC CYCLIC PEPTIDE
著者Pellegrini, M, Liehr, S, Fisher, A.L, Cooperman, B.S, Mierke, D.F.
登録日2000-08-29
公開日2000-11-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure-based optimization of peptide inhibitors of mammalian ribonucleotide reductase.
Biochemistry, 39, 2000
2LOB
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PDZ Domain of CAL (Cystic Fibrosis Transmembrane Regulator-Associated Ligand)
分子名称: Cystic fibrosis transmembrane conductance regulator, Golgi-associated PDZ and coiled-coil motif-containing protein
著者Piserchio, A, Fellows, A, Madden, D.R, Mierke, D.F.
登録日2012-01-20
公開日2012-06-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics.
Biochemistry, 44, 2005
1D6G
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MOLECULAR COMPLEX OF CHOLECYSTOKININ-8 AND N-TERMINUS OF THE CHOLECYSTOKININ A RECEPTOR BY NMR SPECTROSCOPY
分子名称: cholecystokinin type a receptor, cholecystokinin-8
著者Pellegrini, M, Mierke, D.F.
登録日1999-10-13
公開日1999-11-17
最終更新日2021-07-07
実験手法SOLUTION NMR
主引用文献Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy.
Biochemistry, 38, 1999
6MI3
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Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
分子名称: NF-kB ESSENTIAL MODULATOR,NF-kappa-B essential modulator,NF-kB ESSENTIAL MODULATOR
著者Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J.
登録日2018-09-19
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.
Sci Rep, 9, 2019
6MI4
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Structure of the I65M mutant of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
分子名称: NF-kB ESSENTIAL MODULATOR
著者Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J.
登録日2018-09-19
公開日2019-08-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.50009418 Å)
主引用文献The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.
Sci Rep, 9, 2019
1BL1
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PTH RECEPTOR N-TERMINUS FRAGMENT, NMR, 1 STRUCTURE
分子名称: PARATHYROID HORMONE RECEPTOR
著者Pellegrini, M, Bisello, A, Rosenblatt, M, Chorev, M, Mierke, D.F.
登録日1998-07-22
公開日1999-03-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Binding domain of human parathyroid hormone receptor: from conformation to function.
Biochemistry, 37, 1998
1ZOK
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PDZ1 Domain Of Synapse Associated Protein 97
分子名称: Presynaptic protein SAP97
著者Wang, L, Piserchio, A, Mierke, D.F.
登録日2005-05-13
公開日2005-06-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Characterization of the Intermolecular Interactions of Synapse-associated Protein-97 with the NR2B Subunit of N-Methyl-D-aspartate Receptors.
J.Biol.Chem., 280, 2005
2CDX
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BU of 2cdx by Molmil
STRUCTURE OF COBRA CARDIOTOXIN CTXI AS DERIVED FROM NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND DISTANCE GEOMETRY CALCULATIONS
分子名称: CARDIOTOXIN CTX I
著者Jahnke, W, Mierke, D.F, Beress, L, Kessler, H.
登録日1994-09-06
公開日1994-11-30
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure of cobra cardiotoxin CTX I as derived from nuclear magnetic resonance spectroscopy and distance geometry calculations.
J.Mol.Biol., 240, 1994
1L4T
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SOLUTION NMR STRUCTURE OF THE CCK2E3
分子名称: Gastrin/cholecystokinin type B receptor
著者Giragossian, C, Mierke, D.F.
登録日2002-03-05
公開日2003-01-28
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin-2 receptor
Biochemistry, 41, 2002
1LVR
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BU of 1lvr by Molmil
IC3 of CB1 (L431A,A432L) Bound to G(alpha)i
分子名称: Cannabinoid receptor 1
著者Ulfers, A.L, McMurry, J.L, Miller, A, Wang, L, Kendall, D.A, Mierke, D.F.
登録日2002-05-29
公開日2002-12-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Protein Sci., 11, 2002
1LVQ
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IC3 of CB1 Bound to G(alpha)i
分子名称: Cannabinoid receptor 1
著者Ulfers, A.L, McMurry, J.L, Miller, A, Wang, L, Kendall, D.A, Mierke, D.F.
登録日2002-05-29
公開日2002-12-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Protein Sci., 11, 2002
1KEF
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BU of 1kef by Molmil
PDZ1 of SAP90
分子名称: synapse associated protein-90
著者Piserchio, A, Pellegrini, M, Mehta, S, Blackman, S.M, Garcia, E.P, Marshall, J, Mierke, D.F.
登録日2001-11-15
公開日2002-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The PDZ1 domain of SAP90. Characterization of structure and binding.
J.Biol.Chem., 277, 2002

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