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PDB: 11 件
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
分子名称: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
著者Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
登録日2002-01-06
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
3C0R
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BU of 3c0r by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
分子名称: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
著者Messick, T.E, Marmorstein, R.
登録日2008-01-21
公開日2008-02-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
3BY4
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Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
分子名称: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
著者Messick, T.E, Marmorstein, R.
登録日2008-01-15
公開日2008-02-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
5WMF
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Crystal structure of the Hexameric Ring of Epstein-Barr Virus Nuclear Antigen-1, EBNA1
分子名称: Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2017-07-28
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.
J. Virol., 91, 2017
6PW2
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Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication
分子名称: DNA (62-MER), DNA (62-MER) complementary DNA strand, Epstein-Barr nuclear antigen 1
著者Messick, T.E, Malecka, K.A, Lieberman, P.M.
登録日2019-07-22
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
J.Virol., 93, 2019
6VH6
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BU of 6vh6 by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragment
分子名称: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Epstein-Barr nuclear antigen 1
著者Messick, T.E, Lieberman, P.M.
登録日2020-01-09
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.
Molecules, 25, 2020
6NPP
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Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
分子名称: 3-(phenylethynyl)-2-(1H-pyrrol-1-yl)benzoic acid, EBNA1, Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2019-01-18
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
6NPM
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BU of 6npm by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
分子名称: 5-(phenylethynyl)pyridine-3-carboxylic acid, Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2019-01-17
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
6NPI
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Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
分子名称: ({2-[(4-bromo-5-methyl-1,2-oxazol-3-yl)amino]-2-oxoethyl}sulfanyl)acetic acid, 2-pyrrol-1-ylbenzoic acid, Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2019-01-17
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
5T7X
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Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA
分子名称: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1
著者Malecka, K.A, Messick, T.E, Lieberman, P.M.
登録日2016-09-06
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Oncotarget, 8, 2017
3LBX
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BU of 3lbx by Molmil
Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex
分子名称: Spectrin alpha chain, erythrocyte, Spectrin beta chain
著者Ipsaro, J.J, Harper, S.L, Messick, T.E, Marmorstein, R, Mondragon, A, Speicher, D.W.
登録日2010-01-08
公開日2010-03-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.
Blood, 115, 2010

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件を2024-07-10に公開中

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