7PCK
 
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1DEU
 | | CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN X: A CYSTEINE PROTEASE WITH THE PROREGION COVALENTLY LINKED TO THE ACTIVE SITE CYSTEINE | | 分子名称: | PROCATHEPSIN X | | 著者 | Sivaraman, J, Nagler, D.K, Zhang, R, Menard, R, Cygler, M. | | 登録日 | 1999-11-15 | | 公開日 | 2000-02-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
J.Mol.Biol., 295, 2000
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1Q7L
 | | Zn-binding domain of the T347G mutant of human aminoacylase-I | | 分子名称: | Aminoacylase-1, GLYCINE, ZINC ION | | 著者 | Lindner, H.A, Lunin, V.V, Alary, A, Hecker, R, Cygler, M, Menard, R. | | 登録日 | 2003-08-19 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.
J.Biol.Chem., 278, 2003
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1NPZ
 | | Crystal structures of Cathepsin S inhibitor complexes | | 分子名称: | Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide | | 著者 | Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L. | | 登録日 | 2003-01-20 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Specificity determinants of human cathepsin s revealed
by crystal structures of complexes.
Biochemistry, 42, 2003
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1NQC
 | | Crystal structures of Cathepsin S inhibitor complexes | | 分子名称: | Cathepsin S, N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE | | 著者 | Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Menard, R, Cygler, M, Rath, V.L. | | 登録日 | 2003-01-21 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Specificity determinants of human cathepsin s revealed
by crystal structures of complexes.
Biochemistry, 42, 2003
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1PVJ
 | | Crystal structure of the Streptococcal pyrogenic exotoxin B (SpeB)- inhibitor complex | | 分子名称: | (3R)-3-{[(BENZYLOXY)CARBONYL]AMINO}-2-OXO-4-PHENYLBUTANE-1-DIAZONIUM, pyrogenic exotoxin B | | 著者 | Ziomek, E, Sivaraman, J, Doran, J, Menard, R, Cygler, M. | | 登録日 | 2003-06-27 | | 公開日 | 2004-09-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Inhibition of autoprocessing of the streptococcal pyrogenic exotoxin B (speB). Crystal structure of the proenzyme-inhibitor complex
To be published
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1MHW
 | | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides | | 分子名称: | 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L | | 著者 | Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O. | | 登録日 | 2002-08-21 | | 公開日 | 2002-12-11 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
J.Med.Chem., 45, 2002
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