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PDB: 33 results

2HC1
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BU of 2hc1 by Molmil
Engineered catalytic domain of protein tyrosine phosphatase HPTPbeta.
Descriptor: ACETATE ION, CHLORIDE ION, Receptor-type tyrosine-protein phosphatase beta
Authors:Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
2HC2
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BU of 2hc2 by Molmil
Engineered protein tyrosine phosphatase beta catalytic domain
Descriptor: MAGNESIUM ION, Receptor-type tyrosine-protein phosphatase beta, SODIUM ION
Authors:Evdokimov, A.G, Pokross, M, Walter, R, Mekel, M.
Deposit date:2006-06-15
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
Acta Crystallogr.,Sect.D, 62, 2006
2HBU
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BU of 2hbu by Molmil
Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Evdokimov, A.G, Walter, R.L, Mekel, M, Pokross, M.E, Kawamoto, R, Boyer, A.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor
To be Published
2HBT
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BU of 2hbt by Molmil
Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Evdokimov, A.G, Walter, R.L, Mekel, M, Pokross, M.E, Kawamoto, R, Boyer, A.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor
To be Published
2GKO
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BU of 2gko by Molmil
S41 Psychrophilic Protease
Descriptor: CALCIUM ION, SODIUM ION, microbial serine proteinases; subtilisin, ...
Authors:Walter, R.L, Mekel, M.J, Grayling, R.A, Arnold, F.H, Wintrode, P.L, Almog, O.
Deposit date:2006-04-03
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The crystal structures of the psychrophilic subtilisin S41 and the mesophilic subtilisin Sph reveal the same calcium-loaded state.
Proteins, 74, 2009
2H02
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BU of 2h02 by Molmil
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Descriptor: Protein tyrosine phosphatase, receptor type, B,, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Gray, J.L, Peters, K.G, Maier, M.B, Amarasinghe, K.D, Clark, C.M, Nichols, R.
Deposit date:2006-05-13
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Bioorg.Med.Chem.Lett., 16, 2006
2H04
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BU of 2h04 by Molmil
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Descriptor: Protein tyrosine phosphatase, receptor type, B,, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Gray, J.L, Peters, K.G, Maier, M.B, Amarasinghe, K.D, Clark, C.M, Nichols, R.
Deposit date:2006-05-13
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Bioorg.Med.Chem.Lett., 16, 2006
2H03
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BU of 2h03 by Molmil
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
Descriptor: (4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Gray, J.L, Peters, K.G, Maier, M.B, Amarasinghe, K.D, Clark, C.M, Nichols, R.
Deposit date:2006-05-13
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Bioorg.Med.Chem.Lett., 16, 2006
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