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PDB: 16 件

5TJ5
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Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase
分子名称: V-type proton ATPase subunit a, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ...
著者Mazhab-Jafari, M.T, Rohou, A, Schmidt, C, Bueler, S.A, Benlekbir, S, Robinson, C.V, Rubinstein, J.L.
登録日2016-10-03
公開日2016-10-26
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase.
Nature, 539, 2016
3SEA
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BU of 3sea by Molmil
Structure of Rheb-Y35A mutant in GDP- and GMPPNP-bound forms
分子名称: ACETATE ION, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ...
著者Mazhab-Jafari, M.T, Marshall, C.B, Ishiyama, N, Vuk, S, Ikura, M.
登録日2011-06-10
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis.
Structure, 20, 2012
4O25
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BU of 4o25 by Molmil
Structure of Wild Type Mus musculus Rheb bound to GTP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M.
登録日2013-12-16
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
J.Biol.Chem., 289, 2014
4O2L
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BU of 4o2l by Molmil
Structure of Mus musculus Rheb G63A mutant bound to GTP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GTP-binding protein Rheb, ...
著者Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M.
登録日2013-12-17
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
J.Biol.Chem., 289, 2014
4O2R
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BU of 4o2r by Molmil
Structure of Mus musculus Rheb G63V mutant bound to GDP
分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M.
登録日2013-12-17
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
J.Biol.Chem., 289, 2014
8GKC
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BU of 8gkc by Molmil
Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640 - C2 refinement
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, denifanstat
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2023-03-17
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
7KDV
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BU of 7kdv by Molmil
Murine core lysosomal multienzyme complex (LMC) composed of acid beta-galactosidase (GLB1) and protective protein cathepsin A (PPCA, CTSA)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ...
著者Gorelik, A, Illes, K, Hasan, S.M.N, Nagar, B, Mazhab-Jafari, M.T.
登録日2020-10-09
公開日2021-03-17
最終更新日2021-05-26
実験手法ELECTRON MICROSCOPY (4.59 Å)
主引用文献Structure of the murine lysosomal multienzyme complex core.
Sci Adv, 7, 2021
7TUI
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Structure of C. albicans FAS in an inhibited state
分子名称: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2022-02-02
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structure of C. albicans FAS in an inhibited state.
Not published
6WC7
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Acyl carrier protein (ACP) domain bound to dehydratase (DH) domain in fungal fatty acid synthase (FAS)
分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2020-03-29
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Steric occlusion regulates proximal interactions of acyl carrier protein domain in fungal fatty acid synthase.
Commun Biol, 3, 2020
8EYI
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BU of 8eyi by Molmil
Atomic model of the core modifying region of human fatty acid synthase
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2022-10-27
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
8EYK
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BU of 8eyk by Molmil
Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640
分子名称: Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, denifanstat
著者Hasan, S.M.N, Keszei, A, Mazhab-Jafari, M.T.
登録日2022-10-27
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Nat Commun, 14, 2023
8T7T
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BU of 8t7t by Molmil
CryoEM structure of the HisRS-like domain of human GCN2
分子名称: eIF-2-alpha kinase GCN2
著者Yin, J.Z, Keszei, A.F.A, Mazhab-Jafari, M.T, Sicheri, F.
登録日2023-06-21
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献CryoEM structure of the HisRS-like domain of human GCN2
To Be Published
6U5T
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BU of 6u5t by Molmil
Electron cryomicroscopy Structure of S. cerevisiae FAS in the Apo state
分子名称: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2019-08-28
公開日2019-10-16
最終更新日2019-10-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5U
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BU of 6u5u by Molmil
Electron cryomicroscopy Structure of S. cerevisiae FAS in the KS-stalled state
分子名称: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2019-08-28
公開日2019-10-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5V
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BU of 6u5v by Molmil
Electron cryomicroscopy Structure of C. albicans FAS in the Apo state
分子名称: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2019-08-28
公開日2019-10-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5W
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BU of 6u5w by Molmil
Electron cryomicroscopy structure of C. albicans FAS in the KS-stalled state
分子名称: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
著者Lou, J.W, Mazhab-Jafari, M.T.
登録日2019-08-28
公開日2019-10-16
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019

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件を2024-07-24に公開中

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