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PDB: 99 results
2F36
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BU of 2f36 by Molmil
Crystal Structure of the GluR5 Ligand Binding Core Dimer with Glutamate At 2.1 Angstroms Resolution
Descriptor: GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1, GLUTAMIC ACID, ...
Authors:Mayer, M.L.
Deposit date:2005-11-18
Release date:2006-04-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
J.Neurosci., 26, 2006
2F34
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BU of 2f34 by Molmil
Crystal Structure of the GluR5 Ligand Binding Core Dimer with UBP310 At 1.74 Angstroms Resolution
Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Mayer, M.L.
Deposit date:2005-11-18
Release date:2006-04-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
J.Neurosci., 26, 2006
2F35
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BU of 2f35 by Molmil
Crystal Structure of the GluR5 Ligand Binding Core with UBP302 At 1.87 Angstroms Resolution
Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Mayer, M.L.
Deposit date:2005-11-18
Release date:2006-04-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
J.Neurosci., 26, 2006
5CMB
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BU of 5cmb by Molmil
Mnemiopsis leidyi ML032222a iGluR LBD R703K mutant glycine complex
Descriptor: GLYCINE, MAGNESIUM ION, ML032222a iGluR, ...
Authors:Mayer, M.L, Thomas, A.
Deposit date:2015-07-16
Release date:2016-07-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Molecular lock regulates binding of glycine to a primitive NMDA receptor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CMC
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BU of 5cmc by Molmil
Mnemiopsis leidyi ML032222a iGluR LBD E423S mutant glycine complex
Descriptor: GLYCINE, MAGNESIUM ION, ML032222a iGluR, ...
Authors:Mayer, M.L, Thomas, A.
Deposit date:2015-07-16
Release date:2016-07-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Molecular lock regulates binding of glycine to a primitive NMDA receptor.
Proc.Natl.Acad.Sci.USA, 113, 2016
1IIT
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BU of 1iit by Molmil
GLUR0 LIGAND BINDING CORE COMPLEX WITH L-SERINE
Descriptor: SERINE, Slr1257 protein
Authors:Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:2001-04-24
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
J.Mol.Biol., 311, 2001
1II5
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BU of 1ii5 by Molmil
CRYSTAL STRUCTURE OF THE GLUR0 LIGAND BINDING CORE COMPLEX WITH L-GLUTAMATE
Descriptor: GLUTAMIC ACID, Slr1257 protein
Authors:Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:2001-04-20
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
J.Mol.Biol., 311, 2001
1IIW
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BU of 1iiw by Molmil
GLUR0 LIGAND BINDING CORE: CLOSED-CLEFT LIGAND-FREE STRUCTURE
Descriptor: Slr1257 protein
Authors:Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:2001-04-24
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
J.Mol.Biol., 311, 2001
1TXF
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BU of 1txf by Molmil
CRYSTAL STRUCTURE OF THE GLUR5 LIGAND BINDING CORE IN COMPLEX WITH GLUTAMATE AT 2.1 ANGSTROM RESOLUTION
Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 1
Authors:Mayer, M.L.
Deposit date:2004-07-04
Release date:2005-02-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity
Neuron, 45, 2005
1TT1
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BU of 1tt1 by Molmil
CRYSTAL STRUCTURE OF THE GLUR6 LIGAND BINDING CORE IN COMPLEX WITH KAINATE 1.93 A RESOLUTION
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor, ionotropic kainate 2
Authors:Mayer, M.L.
Deposit date:2004-06-21
Release date:2005-02-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity
Neuron, 45, 2005
1S50
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BU of 1s50 by Molmil
X-ray structure of the GluR6 ligand binding core (S1S2A) in complex with glutamate at 1.65 A resolution
Descriptor: GLUTAMIC ACID, Glutamate Receptor 6
Authors:Mayer, M.L.
Deposit date:2004-01-19
Release date:2005-02-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity
Neuron, 45, 2005
1S9T
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BU of 1s9t by Molmil
Crystal structure of the GLUR6 ligand binding core in complex with quisqualate at 1.8A resolution
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, CHLORIDE ION, Glutamate receptor, ...
Authors:Mayer, M.L.
Deposit date:2004-02-05
Release date:2005-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.
Neuron, 45, 2005
1SD3
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BU of 1sd3 by Molmil
Crystal structure of the GLUR6 ligand binding core in complex with 2S,4R-4-methylglutamate at 1.8 Angstrom resolution
Descriptor: 2S,4R-4-METHYLGLUTAMATE, Glutamate receptor, ionotropic kainate 2
Authors:Mayer, M.L.
Deposit date:2004-02-12
Release date:2005-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.
Neuron, 45, 2005
1S7Y
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BU of 1s7y by Molmil
Crystal structure of the GluR6 ligand binding core in complex with glutamate at 1.75 A resolution orthorhombic form
Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2 precursor
Authors:Mayer, M.L.
Deposit date:2004-01-30
Release date:2005-02-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity
Neuron, 45, 2005
3C33
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BU of 3c33 by Molmil
Crystal structure of GluR5 ligand-binding core in complex with potassium at 1.78 Angstrom resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Mayer, M.L.
Deposit date:2008-01-27
Release date:2008-06-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Molecular basis of kainate receptor modulation by sodium.
Neuron, 58, 2008
3C36
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BU of 3c36 by Molmil
Crystal structure of GluR5 ligand-binding core in complex with ammonium ions at 1.68 Angstrom resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, AMMONIUM ION, CHLORIDE ION, ...
Authors:Mayer, M.L.
Deposit date:2008-01-27
Release date:2008-06-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Molecular basis of kainate receptor modulation by sodium.
Neuron, 58, 2008
3C34
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BU of 3c34 by Molmil
Crystal structure of GluR5 ligand-binding core in complex with rubidium at 1.82 Angstrom resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Mayer, M.L.
Deposit date:2008-01-27
Release date:2008-06-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Molecular basis of kainate receptor modulation by sodium.
Neuron, 58, 2008
3C35
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BU of 3c35 by Molmil
Crystal structure of GluR5 ligand-binding core in complex with cesium at 1.97 Angstrom resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CESIUM ION, CHLORIDE ION, ...
Authors:Mayer, M.L.
Deposit date:2008-01-27
Release date:2008-06-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Molecular basis of kainate receptor modulation by sodium.
Neuron, 58, 2008
3C32
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BU of 3c32 by Molmil
Crystal structure of GluR5 ligand-binding core in complex with sodium at 1.72 Angstrom resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Mayer, M.L.
Deposit date:2008-01-27
Release date:2008-06-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Molecular basis of kainate receptor modulation by sodium.
Neuron, 58, 2008
3C31
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BU of 3c31 by Molmil
Crystal structure of GluR5 ligand-binding core in complex with lithium at 1.49 Angstrom resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Mayer, M.L.
Deposit date:2008-01-27
Release date:2008-06-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Molecular basis of kainate receptor modulation by sodium.
Neuron, 58, 2008
2GFE
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BU of 2gfe by Molmil
Crystal structure of the GluR2 A476E S673D Ligand Binding Core Mutant at 1.54 Angstroms Resolution
Descriptor: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
Authors:Mayer, M.L.
Deposit date:2006-03-21
Release date:2006-08-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate.
J.Neurosci., 26, 2006
2I0C
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BU of 2i0c by Molmil
Crystal structure of the GluR6 ligand binding core dimer crosslinked by disulfide bonds between Y490C and L752C at 2.25 Angstroms Resolution
Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2
Authors:Mayer, M.L.
Deposit date:2006-08-10
Release date:2006-11-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Conformational restriction blocks glutamate receptor desensitization.
Nat.Struct.Mol.Biol., 13, 2006
2I0B
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BU of 2i0b by Molmil
Crystal structure of the GluR6 ligand binding core ELKQ mutant dimer at 1.96 Angstroms Resolution
Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2, ...
Authors:Mayer, M.L.
Deposit date:2006-08-10
Release date:2006-11-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Conformational restriction blocks glutamate receptor desensitization.
Nat.Struct.Mol.Biol., 13, 2006
2OJT
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BU of 2ojt by Molmil
Structure and mechanism of kainate receptor modulation by anions
Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, BROMIDE ION, Glutamate receptor, ...
Authors:Mayer, M.L.
Deposit date:2007-01-14
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and mechanism of kainate receptor modulation by anions.
Neuron, 53, 2007
4UQK
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BU of 4uqk by Molmil
Electron density map of GluA2em in complex with quisqualate and LY451646
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2
Authors:Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (16.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014

 

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